Canine cutaneous lupus erythematosus is recognised in a variety of different forms. The most common chronic form of the disease is the classical facial dominant form, discoid lupus erythematosus. In addition, other chronic variants that have been described include mucocutaneous lupus erythematosus, ...

This review discusses the different subtypes of cutaneous canine lupus sensu stricto that share a common histopathological pattern. The most frequent type of cutaneous canine lupus sensu stricto in the dog is localized discoid lupus erythematosus. Other variants are generalized discoid lupus ...

Canine cutaneous lupus erythematosus is recognised in a variety of different forms. The most common chronic form of the disease is the classical facial dominant form, discoid lupus erythematosus. In addition, other chronic variants that have been described include mucocutaneous lupus erythematosus, ...

Cutaneous lupus erythematosus (CLE) is an autoimmune, chronic-relapsing disease that can present as an isolated skin disease or as a manifestation within the spectrum of systemic lupus erythematosus. The pathogenesis of CLE is multifactorial and involves genetic predisposition, environmental...

Since the first description of discoid lupus erythematosus (LE) in two dogs in 1979, the spectrum of canine cutaneous lupus erythematosus (CLE) variants has expanded markedly. In this review, we first propose an adaptation of the Gilliam-Sontheimer classification of CLE for dogs. We then review the ...

Both lupus erythematosus (LE) and pemphigus foliaceus are rare autoimmune diseases in dogs. Pathogenetically, both diseases are based on the formation of autoantibodies, which in lupus are anti-nuclear antibodies (ANA). In pemphigus, on the other hand, the autoantibodies are directed against cell...

Canine vesicular cutaneous lupus erythematosus (CVCLE) is a rare autoimmune skin disease typical of the breeds Rough Collie and Shetland Sheepdog, affecting also animals resulting from their crosses. Clinical signs are mostly dermatologic and include vesicles and/or bullae, and ulcerations in...

Tetracycline and niacinamide (TCN) were administered to 12 dogs with discoid lupus erythematosus (DLE), 3 dogs with perianal/perivulvar lupus erythematosus (PPLE), 1 dog with vesicular cutaneous lupus erythematosus (VCLE), and 1 dog with exfoliative cutaneous lupus erythematosus (ECLE). Eight of 12 ...

Clinical and histological features of an erosive disease in the rough collie and Shetland sheepdog are most consistent with a vesicular variant of cutaneous lupus erythematosus (VCLE). This paper reports the immunopathological findings of canine VCLE using samples from 17 affected dogs. Lesional...

Immunomodulatory and immunosuppressive molecules are used for the therapy of cutaneous lupus, with various success rates depending on the different clinical form considered. Currently, the most effective therapy for vesicular lupus appears to be calcineurin inhibitors, with a good prognosis in 75%...