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VetMed Resource

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Abstract

In humans and dogs, toxic epidermal necrolysis (TEN) is a life-threatening dermatosis characterized by sudden epidermal death resulting in extensive skin detachment. There is little information on the pathogenesis of keratinocyte cell death in canine TEN. We studied the occurrence of apoptosis in...

Author(s)
Banovic, F.; Dunston, S.; Linder, K. E.; Rakich, P.; Olivry, T.
Publisher
American College of Veterinary Pathologists Inc., Lawrence, USA
Citation
Veterinary Pathology, 2017, 54, 2, pp 249-253
AbstractFull Text

The study was based on a mestizo canine of two and a half months old, weighing 3.5 kg, with loss of approximately 60% of skin at the thoracolumbar level and with the perianal area compromised. The dog had previously been treated for hemorrhagic gastroenteritis, with fluid therapy and intravenous...

Author(s)
Murcia-Marroquín, E. H.; Camacho-Castro, A.; Salcedo-Sánchez, H. D.; Vaquiro-Rumique, A. R.
Publisher
Centro Nacional de Sanidad Agropecuaria, La Habana, Cuba
Citation
Revista de Salud Animal, 2018, 40, 2, pp unpaginated
Abstract

Canine toxic epidermal necrosis (TEN), a rare and life-threatening cutaneous drug reaction, traditionally has been described as full-thickness devitalization of the epidermis with minimal dermal inflammation; however, few reports detail the histologic findings. We characterize the clinical features ...

Author(s)
Banovic, F.; Olivry, T.; Bazzle, L.; Tobias, J. R.; Atlee, B.; Zabel, S.; Hensel, N.; Linder, K. E.
Publisher
American College of Veterinary Pathologists Inc., Lawrence, USA
Citation
Veterinary Pathology, 2015, 52, 2, pp 321-330
Abstract

It has been reported that apoptotic keratinocytes were not observed in dogs with toxic epidermal necrolysis (TEN). Here, we describe a dog with TEN in which apoptotic cells were found in the epidermis. A 13-year-old female mongrel dog was presented with acute and extensive erythema, vesicles and...

Author(s)
Nishiyama, T.; Iyori, K.; Iwasaki, T.; Nishifuji, K.
Publisher
Japanese Society of Veterinary Dermatology, Tokyo, Japan
Citation
Japanese Journal of Veterinary Dermatology, 2015, 21, 2, pp 71-75
Abstract

A four-year-old Staffordshire bull terrier presented with severe and rapidly progressive blistering skin disease, which was consistent clinically with toxic epidermal necrolysis. There had been an acute onset of generalised erythema, pustulosis and blister formation of the ventral abdomen, ventral...

Author(s)
Bateman, F. L.; Nimmo, J.; Shipstone, M. A.
Publisher
Australian Small Animal Veterinary Association, St. Leonards, Australia
Citation
Australian Veterinary Practitioner, 2012, 42, 1, pp 200-205
Abstract

Background: Human erythema multiforme (EM) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) are separate conditions. There is no consensus on classification criteria for the eponymous diseases in animals. Results: Animal EM is very different from 90% of human EM, which is herpes...

Author(s)
Yager, J. A.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Dermatology, 2014, 25, 5, pp 406-e64
Abstract

This case report describes three cases of canine cutaneous drug hypersensitivity with systemic signs presumed to be secondary to perioperative drug administration suspected to induce either erythema multiforme (EM) or Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN). Tentative...

Author(s)
Sasaki, K.; Mutoh, T.; Shiga, T.; Gómez de Segura, I. Á.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record Case Reports, 2018, 6, 2, pp e000613
Abstract

We report a case of asplenic fulminant sepsis in Australia following a dog bite which was complicated by toxic epidermal necrolysis/Stevens-Johnson syndrome (TENS/SJS). Capnocytophaga canimorsus, the infective organism, is a rare cause of septicaemia: a high degree of suspicion of this unusual...

Author(s)
Teo, K. G.; Anavekar, N. S.; Yazdabadi, A.; Ricketts, S.
Publisher
New Zealand Medical Association, Wellington, New Zealand
Citation
New Zealand Medical Journal, 2012, 125, 1358, pp 74-77
Abstract

A 3-year-old intact female mixed breed dog presented with lethargy, anorexia, vomiting and a history of pseudopregnancy with severe mastitis. The animal had been treated for pseudopregnancy with cabergoline and furosemide. Complete blood count showed leukocytosis, neutrophilia and septicemia....

Author(s)
Saberi, M.; Kheirandish, R.; Shojaeepour, S.
Publisher
Online Journal of Veterinary Research, Toowoomba, Australia
Citation
Online Journal of Veterinary Research, 2014, 18, 7, pp 521-527
Abstract

Staphylococcal toxic shock syndrome (STSS) is a rare toxinic dermatosis recently described in dogs. In this syndrome, also reported in man, the toxin toxic shock syndrome toxin-1 (TSST-1) acts as a superantigen and triggers the massive release of lymphocytic cytokines (IL 1, IL6, TNFα). Two cases...

Author(s)
Guaguère, É.; Muller, A.; Degorce-Rubiales, F.
Publisher
Elsevier Masson, Issy-les Moulineaux Cedex, France
Citation
Pratique Médicale et Chirurgicale de l'Animal de Compagnie, 2012, 47, 3, pp 73-80

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