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Abstract

The blood brain barrier is the major obstacle to treating lysosomal storage disorders of the central nervous system such as canine fucosidosis. This barrier was overcome by three, monthly injections of recombinant canine α-L-fucosidase enzyme were given intracisternally. In dogs treated from 8...

Author(s)
Kondagari, G. S.; King, B. M.; Thomson, P. C.; Williamson, P.; Clements, P. R.; Fuller, M.; Hemsley, K. M.; Hopwood, J. J.; Taylor, R. M.
Publisher
Academic Press, London, UK
Citation
Experimental Neurology, 2011, 230, 2, pp 218-226
Abstract

Rapid progress in knowledge of the organization of the dog genome has facilitated the identification of the mutations responsible for numerous monogenic diseases, which usually present a breed-specific distribution. The majority of these diseases have clinical and molecular counterparts in humans....

Author(s)
Switonski, M.
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Journal of Applied Genetics, 2020, 61, 2, pp 179-186
Abstract

Background: Low vitamin D increases the risk of immune-mediated disease (IMD) in human beings and rodent models. Vitamin D metabolites, particularly 1,25(OH)2D3, modulate gene expression of immune cells and may attenuate immune pathways that drive IMD. Hypothesis/objectives: Our primary hypothesis...

Author(s)
Mick, P. J.; Peng, S. A.; Loftus, J. P.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2019, 6, July, pp 247
Abstract

Canine sarcoptic mange is a highly pruritic and contagious skin disease caused by the mite Sarcoptes scabiei var. canis. This case series describes the clinical, parasitological, and serological follow-up of a cohort of eight adult Saint Bernard dogs with confirmed sarcoptic mange, treated orally...

Author(s)
Moog, F.; Brun, J.; Bourdeau, P.; Cadiergues, M. C.
Publisher
Hindawi, London, UK
Citation
Case Reports in Veterinary Medicine, 2021, 2021, 6639017,
Abstract

Background: Periodontal disease (PD) is a highly prevalent inflammatory disease in dogs. This disease is initiated by a polymicrobial biofilm on the teeth surface, whose control includes its prevention and removal. Recently, it was shown that nisin displays antimicrobial activity against canine...

Author(s)
Cunha, E.; Freitas, F. B.; Braz, B. S.; Silva, J. M. da; Tavares, L.; Veiga, A. S.; Oliveira, M.
Publisher
MDPI AG, Basel, Switzerland
Citation
Antibiotics, 2020, 9, 4,
AbstractFull Text

The present work aimed to have a look at the Flow cytometry analysis of dog bone marrow stem cellular floor protein expression. Five healthful mongrel dogs (3 male dogs and 2 female dogs). The dogs weight was (24-50 kg b.Wt) and common age was (8-24 Months), the dogs examined towards diseases. The ...

Author(s)
Rakeid, R. M.; El-Khir, W. A.; Hashim, A. E.; Torky, H. A.
Publisher
Faculty of Veterinary Medicine, Alexandria University, Behira, Egypt
Citation
Alexandria Journal of Veterinary Sciences, 2020, 66, 2, pp 62-66
Abstract

Background: Canine packed red blood cells (pRBCs) can be stored under refrigeration for several days; however, cellular metabolism remains active inside the units, thus producing substances that affect their quality. Objectives: We aimed to evaluate hematologic, biochemical, and blood gas variable...

Author(s)
Rodrigues, R. R.; Kayano, C. Y.; Santos, V. P. dos; Moroz, L. R.; Fantoni, D. T.; Ambrósio, A. M.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2020, 49, 2, pp 198-206
Abstract

The current level of morbidity and mortality among dogs due to canine distemper virus infection raise concerns about the effectiveness of commercially available DHLPPi vaccines. The prevalence of the disease despite vaccination warranted the evaluation of the potency of vaccines that are used for...

Author(s)
Adejumobi, O. A.; Babajinmi-Joseph, B.; Omobowale, T. O.; Nottidge, H. O.
Publisher
Biomedical Communications Group, Ibadan, Nigeria
Citation
African Journal of Biomedical Research, 2019, 22, 3, pp 333-338
Abstract

Renal hyperparathyroidism (RHPT) is one of the main complications in dogs affected with Chronic Kidney Disease (CKD). The measurement of serum parathyroid hormone (PTH) could be of clinical utility for the disease's treatment and follow-up; however, PTH is not routinely determined due to limited...

Author(s)
Zambarbieri, J.; Tagliasacchi, F.; Moretti, P.; Giordano, A.; Scarpa, P.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2020, 10, 12,
AbstractFull Text

Hepcidin is a peptide hormone and the main regulator of iron metabolism in the body. It was discovered in human serum and urine in 2000 and named liver expressed antimicrobial protein-1 (LEAP-1). Research of antimicrobial peptides in relation to inflammatory response was conducted by Tomas Ganz. He ...

Author(s)
Artuković Nadinić, I.; Barić Rafaj, R.; Bedrica, L.; Pavlak, M.; Lipar, M.; Mrljak, V.
Publisher
Hrvatski veterinarski institut, Centar za peradarstvo, Zagreb, Croatia
Citation
Veterinarska Stanica, 2020, 51, 2, pp 187-198

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