Objectives: To document the prevalence of cardiac abnormalities in dogs with steroid-responsive meningitis arteritis and to assess resolution of these abnormalities following corticosteroid therapy. Materials and methods: Steroid-responsive meningitis arteritis was diagnosed based on signalment,...
Author(s)
Spence, S.; French, A.; Penderis, J.; Macfarlane, L.; Gutierrez-Quintana, R.; Dickson, L.; Holmes, K.; McLauchlan, G.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2019, 60, 4, pp 204-211
Objectives: The primary objective of the study was to describe the MRI findings in dogs diagnosed with steroidresponsive meningitis-arteritis. Methods: This was a retrospective case series. The clinical records of six UK referral hospitals were searched for dogs diagnosed with steroid-responsive ...
Author(s)
Jones, B.; Agthe, P.; Scarpante, E.; Crawford, A.; Black, V.; Espadas-Santiuste, I.; Formoso, S.; Walker, D.; Fraser, A.
Publisher
British Small Animal Veterinary Association (BSAVA), Quedgeley, UK
Citation
BSAVA Congress Proceedings 2022, 2022,
Background: Steroid-responsive meningitis-arteritis (SRMA) is a frequently occurring form of meningitis in dogs which manifests in vasculitis-arteritis of the meningeal vessels in the spinal cord and in the brain. The aetiology is presumably autoimmune but no definite background has been justified...
Author(s)
Johansen, M.; Balogh, É.
Publisher
Herman Ottó Institute Nonprofit Ltd., Budapest, Hungary
Citation
Magyar Állatorvosok Lapja, 2018, 140, 2, pp 101-108
Steroid responsive meningitis arteritis (SRMA) is an aberrant Th2-mediated systemic inflammatory disease in dogs. The etiopathogenesis still remains unclear as no triggering pathogen or autoantigen could be found so far. Hypothesis. Large high-density peptide microarrays are a suitable screening...
Author(s)
Nessler, J. N.; Tipold, A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2023, 18, 4,
In the context to fester further research on the etiology of steroid-responsive meningitis-arteritis (SRMA), it is of uttermost importance to evaluate dogs with a confirmed diagnosis. The aim of the current questionnaire-based study was to investigate whether typical clinical signs such as...
Author(s)
Cordes, A.; Nebler, J.; Tipold, A.; Kleinsorgen, C.; Flegel, T.; Hilpert, E.
Publisher
Schlütersche Verlagsgesellschaft GmbH & Co. KG, Hannover, Germany
Citation
Praktische Tierarzt, 2023, 104, 4, pp 326-336
Introduction: This retrospective multicentric study aims to evaluate the ability of CRP concentration to differentiate between dogs diagnosed with IMPA and SRMA. C-reactive protein (CRP) is a marker of inflammation widely used in two of the most commonly diagnosed immune-mediated diseases in ...
Author(s)
Indzhova, V.; Czopowicz, M.; Kilpatrick, S.; Gutierrez-Quintana, R.; Brocal, J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2023, 9, February,
Extracellular traps (ETs) are DNA networks formed by immune cells to fight infectious diseases by catching and attacking pathogenic microorganisms. Uncontrolled ET formation or impaired ET clearance can cause tissue and organ damage. Steroid-responsive meningitis-arteritis (SRMA) represents an...
Author(s)
Wohlsein, J. C.; Meurer, M.; Neßler, J.; Wohlsein, P.; Köckritz-Blickwede, M. von; Baumgärtner, W.; Tipold, A.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2022, 8, May,
Treatment with high corticosteroid dosages for steroid-responsive meningitis-arteritis (SRMA) is correlated with severe adverse effects and worse quality of life. In order to improve immunosuppression and decrease dosage and duration of glucocorticoid treatment, a second immunosuppressive drug is...
Author(s)
Giraud, L.; Girod, M.; Cauzinille, L.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2021, 57, 1, pp 1-7
This article reports on a case of steroid responsive meningitis-arteritis (SRMA) in an 18-month-old female neutered Beagle with a history of anorexia and lethargy. On examination the dog shows cervical hyperesthesia and has a rectal temperature of 39.8°C. Cerebral spinal fluid (CSF) analysis...
Publisher
RCVS Knowledge, London, UK
Citation
Veterinary Evidence, 2019, 4, 1, pp unpaginated
Background: Relapses in steroid-responsive meningitis-arteritis (SRMA) are frequently observed but specific treatment protocols to address this problem are sparsely reported. Standard treatment includes prolonged administration of glucocorticoids as monotherapy or in combination with...
Author(s)
Günther, C.; Steffen, F.; Alder, D. S.; Beatrice, L.; Geigy, C.; Beckmann, K.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record, 2020, 187, 1, pp e7-e7