Soft tissue sarcomas are pleiotropic tumors of mesenchymal cell origin. These tumors are rare in humans but common in veterinary practice, where they comprise up to 15% of canine skin and subcutaneous cancers. Because they present similar morphologies, primary sites, and growth characteristics,...

Soft tissue sarcoma (STM) has a mesenchymal origin, occurring most commonly in middle-aged to elderly dogs. The aim of this paper is to report a case of a five-year-old female German Shepherd canine, unneutered, weighing 32 kg, treated at the Veterinary Hospital of the University of Passo Fundo...

Stained cytological specimens from 24 dogs with spontaneous soft tissue sarcomas [fibrosarcoma (n=8), liposarcoma (n=8) and haemangiopericytoma (n=8)], and 24 dogs with reactive connective tissue lesions [granulation tissue (n=12) and dermal fibrosis (n=12)] were analysed by computer-assisted...

Stained cytological specimens from twenty-four canine cutaneous soft tissue sarcomas and twenty-four canine spindle cell reactive proliferations were analyzed by computer-assisted nuclear morphometry. In each case, the nuclei of at least 100 neoplastic and reactive spindle cells were measured. The...

Adjuvant treatments are recommended in dogs with incompletely excised cutaneous soft-tissue sarcoma (STS) to reduce the risk of local recurrence (LR), although guidelines are lacking on how to manage clean but close margins (CbCM). This retrospective study investigates the impact of CbCM on LR of ...

An 8-year-old, spayed female, Doberman pinscher dog was presented to the Ontario Veterinary College Health Sciences Center for evaluation of a large subcutaneous mass on the right cranial ventral abdomen. Computed tomography localized a 6 × 7 cm soft tissue mass to the site of a...

Objective: To investigate the ability of neutrophil-to-lymphocyte ratio and albumin-to-globulin ratio to differentiate soft tissue sarcoma from benign soft tissue tumours. Methods: A retrospective study of pretreatment haematology and biochemistry in dogs diagnosed with soft tissue sarcoma or...

Canine rhabdomyosarcoma (RMS) presents a diagnostic challenge due to its overlapping histologic features with other soft tissue sarcomas. The diagnosis of RMS currently relies on positive immunohistochemical (IHC) labeling for desmin; however, desmin expression is also observed in non-RMS tumors....

Human and canine sarcomas are difficult to treat soft tissue malignancies with an urgent need for new improved therapeutic options. Local recurrence rates for humans are between 10%-30%, and 30%-40% develop metastases. Outcomes for dogs with sarcoma vary with grade but can be similar. Pet dogs...

Background: Cutaneous neoplastic diseases are the most and second-most frequently reported tumors in male and female dogs, respectively. The aims of this study were to report the occurrence of canine cutaneous tumors in a pathology laboratory located in Northern Portugal between 2014 and 2020, and...