Background: Canine atopic dermatitis (AD) is a complex multifactorial disease characterised by an exaggerated immunological response. Little is known about the role that cutaneous and circulating chemokines play in disease severity. Objective: To evaluate the messenger (m)RNA and protein levels of...
Author(s)
Santoro, D.; Archer, L.; Chong, E.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2022, 33, 3, pp 195-e56
A more complete understanding of canine T-lymphocyte immunity is necessary for improving diagnostic and therapeutic approaches to canine diseases, developing cell-based canine immunotherapeutics, and evaluating dogs as large mammal models for comparative immunology research. The aim of this study...
Author(s)
Bauman, A. B.; Moeller, C. E.; Soileau, A. M.; Goodermuth, C. E.; Costa, V. R.; Schaumburg, J. C.; Pucheu-Haston, C. M.; Welborn, N. D.; Dehghanpir, S. D.; Mitchell, M. A.; Withers, S. S.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2022, 246,
Atopic dermatitis (AD) is an allergic skin disease that causes significant morbidity and affects multiple species. AD is highly prevalent in companion dogs, and the clinical management of the disease remains challenging. An improved understanding of the immunologic and genetic pathways that lead to ...
Author(s)
Früh, S. P.; Saikia, M.; Eule, J.; Mazulis, C. A.; Miller, J. E.; Cowulich, J. M.; Oyesola, O. O.; Webb, L. M.; Peng, S. A.; Cubitt, R. L.; Danko, C. G.; Miller, W. H.; Tait Wojno, E. D.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2020, 221,
Interleukins (IL)-17, IL-22, and IL-31 play roles in human atopic dermatitis (AD), but scant information is available on canine AD. Histopathological assessment for interleukin expression is a challenge due to a lack of canine specific antibodies. To evaluate the mRNA and protein expression of...
Author(s)
Shiomitsu, S.; Gillen, J.; Frasca, S.; Santoro, D.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2021, 136, pp 74-80
Background: Canine leishmaniosis (CanL) caused by Leishmania infantum can have several dermatological manifestations. The type of immune response elicited against the parasite appears to be at the basis for such clinical variability. Much of the work in CanL has focused on adaptive immune response...
Author(s)
Ordeix, L.; Montserrat-Sangrà, S.; Martínez-Orellana, P.; Baxarias, M.; Solano-Gallego, L.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2019, 12, 575, pp (5 December 2019)
Canine demodicosis is a common inflammatory parasitic skin disease caused by Demodex mites. House dust mites, such as Dermatophagoides spp., play an important role in the pathogenesis of canine atopic dermatitis (AD). The goal of this experimental work was to investigate whether demodectic dogs...
Author(s)
Oliveira, M. C.; Pajuaba, A. C. A. M.; Bastos, J. E. D.; Mineo, J. R.; Souza, F. P.; Araujo, E. C. B.; Almeida, M. P. O.; Silva, D. A. O.; Taketomi, E. A.; Silva, N. M.
Publisher
Universidade Federal de Uberlândia, Uberlândia, Brazil
Citation
Bioscience Journal, 2020, 36, 6, pp 2172-2185
Background: Canine atopic dermatitis (CAD) is a chronic and inflammatory disease present in veterinary dermatological practice. The inflammation in CAD is triggered by environmental allergens and skin microorganisms, which are responsible for the worsening of cutaneous lesions. This continuous...
Author(s)
Ferreira, T. C.; Lima-Verde, J. F.; Silva Júnior, J. A. da; Ferreira, T. M. V.; Araújo Viana, D. de; Nunes-Pinheiro, D. C. S.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2021, 49, 1782,
The aim of this article is to summarize the treatment of atopic dermatitis, advantages and disadvantages concerning efficacy and safety. Canine atopic dermatitis is a genetically predisposed, inflammatory and puritic skin disease. Atopy can be challenging to diagnose and to treat effectively. These ...
Publisher
Herman Ottó Institute Nonprofit Ltd., Budapest, Hungary
Citation
Magyar Állatorvosok Lapja, 2021, 143, 1, pp 25-38
Background: Canine leishmaniosis (CanL) is associated with an aberrant cutaneous immune response. Few studies have compared cutaneous immune cells among dogs with leishmaniosis or infected without leishmaniosis, and noninfected dogs. Hypothesis/Objective: Evaluate the number of neutrophils,...
Author(s)
Hernandez-Bures, A.; Gillen, J.; Apostolidis, K.; Saridomichelakis, M.; Loria, A. di; Santoro, D.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2020, 32, 2, pp 99-e19
Canine demodicosis is a skin disease caused by excessive proliferation of Demodex spp. genetic, immunological, parasitic and bacteriological factors have been attributed to it's presentation. Canine ehrlichiosis is a disease caused by intracellular rickettsia of the genus Ehrlichia spp., which is...
Author(s)
Florez, A. A.; Rosas, A.; Pinilla, J. C.
Publisher
Pubvet, Maringá, Brazil
Citation
PUBVET, 2020, 14, 7,