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Abstract

Background - Filaggrin (FLG) is a key protein for skin barrier formation and hydration of the stratum corneum. In humans, a strong association between FLG gene mutations and atopic dermatitis has been reported. Although similar pathogenesis and clinical manifestation have been argued in canine...

Author(s)
Kanda, O.; Sasaki, T.; Shiohama, A.; Nishifuji, K.; Amagai, M.; Iwasaki, T.; Kudoh, J.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Dermatology, 2013, 24, 1, pp 25-e7
Abstract

Background: Mycosis fungoides (MF) is an uncommon cutaneous neoplasm in dogs. Treatment options are limited. Total skin electron therapy (TSET) has been suggested as a possible therapy for canine MF. Objective: To describe the use of TSET as palliative treatment for MF in a dog. Results: An adult ...

Author(s)
Santoro, D.; Kubicek, L.; Lu Bo; Craft, W.; Conway, J.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2017, 28, 2, pp e65
Abstract

Autosomal recessive congenital ichthyosis in the American bulldog is characterized by generalized scaling and erythema with adherent scale on the glabrous skin. We had previously linked this disorder to NIPAL4, which encodes the protein ichthyin. Sequencing of NIPAL4 revealed a homozygous single...

Author(s)
Casal, M. L.; Wang Ping; Mauldin, E. A.; Lin, G.; Henthorn, P. S.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2017, 12, 1, pp e0170708
Abstract

A non-epidermolytic ichthyosis has been identified in Golden Retrievers due to a variant in the PNPLA1 gene, and a genetic test is available to detect wild-type, heterozygous and homozygous dogs. The aims of this study were to investigate the prevalence of the PNPLA1 gene variant in Golden...

Author(s)
Graziano, L.; Vasconi, M.; Cornegliani, L.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2018, 5, 2, pp 48
Abstract

Background: Autosomal recessive congenital ichthyosis (ARCI) in golden retrievers is due to a PNPLA1 gene mutation, which plays a role in epidermal lipid organization and metabolism. Topical therapies are used to reduce scaling; however, there are few published efficacy studies. Objectives: To...

Author(s)
Puigdemont, A.; Furiani, N.; Lucia, M. de; Carrasco, I.; Ordeix, L.; Fondevila, D.; Ramió-Lluch, L.; Brazis, P.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2018, 29, 4, pp 323-e113
Abstract

Atopic dermatitis (AD) is a common skin disease encountered in both humans and dogs. Canine AD can be used in the analysis of naturally occurring AD; however, details of clinical comparison have been lacking. The purpose of this study is to compare those clinical features using the human diagnostic ...

Author(s)
Terada, Y.; Nagata, M.; Murayama, N.; Nanko, H.; Furue, M.
Publisher
Wiley-Blackwell, Melbourne, Australia
Citation
Journal of Dermatology, 2011, 38, 8, pp 784-790
Abstract

Alterations of cornification, often described in the dog with the generic and not appropriate term "seborrhea", are numerous and are divided into hereditary and acquired. Among the first, ichthyosis is a rare genodermatosis characterized by hyperkeratosis that involves the entire skin surface....

Author(s)
Ghibaudo, G.
Publisher
Point Vétérinaire Italie s.r.l., Milano, Italy
Citation
Summa, Animali da Compagnia, 2012, 29, 3, pp 6-8
Abstract

Background: A recessive inherited form of lamellar ichthyosis is well recognized in golden retrievers. In this breed, young puppies demonstrate a self-limiting scaling disorder which is commonly recognized by breeders, who use the term "milk crust" to describe this syndrome. Hypothesis/Objectives:...

Author(s)
Roethig, A.; Schildt, K. J. M.; Welle, M. M.; Wildermuth, B. E.; Neiger, R.; Thom, N.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Dermatology, 2015, 26, 4, pp 265-e57
Abstract

Background: Ichthyosis is a dermatological disease characterized by varying degrees of generalized hyperkeratosis and alopecia. Two congenital forms of ichthyosis are recognized in animals: fetalis (IF) and congenita. The disease occurs rarely in cattle, swine, dogs, chickens and a goat; it has not ...

Author(s)
Câmara, A. C. L.; Borges, P. A. C.; Paiva, S. A.; Pierezan, F.; Soto-Blanco, B.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2017, 28, 5, pp 516-e125
Abstract

Background: Congenital, nonepidermolytic cornification disorders phenotypically resembling human autosomal recessive ichthyosis have been described in purebred dog breeds, including Jack Russell terrier (JRT) dogs. One cause of gene mutation important to humans and dogs is transposon insertions....

Author(s)
Credille, K. M.; Minor, J. S.; Barnhart, K. F.; Lee, E.; Cox, M. L.; Tucker, K. A.; Diegel, K. L.; Venta, P. J.; Hohl, D.; Huber, M.; Dunstan, R. W.
Publisher
Blackwell Publishing, Oxford, UK
Citation
British Journal of Dermatology, 2009, 161, 2, pp 265-272

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