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Abstract

Cellular senescence was discovered in cell culture by Hayflick and Moorhead in 1965 in human fibroblasts. It is primarily characterized by irreversible cell cycle arrest and an altered, enlarged morphology. Senescent cells are thought to accumulate with age in a variety of species including mice,...

Author(s)
Merz, S.
Publisher
Freien Universität Berlin, Berlin, Germany
Citation
Age- and tumor-dependent senescence in canine testis and eye, 2019, pp 56 pp.
Abstract

The blood-testis barrier (BTB) consists of different cell-to-cell connections, including tight junction proteins like claudin-11 (CLDN11). For dogs, only limited data is published dealing with these proteins in general. Therefore, their physiological relevance, their postnatal expression, and their ...

Author(s)
Pörtner, C.; Rode, K.; Hollenbach, J.; Thiemeyer, H.; Beineke, A.; Günzel-Apel, A. R.; Brehm, R.
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2020, 148, pp 122-131
Abstract

Background: Testicular tumours are common in dogs and in many cases do not give rise to clinical signs. In other cases, signs of feminization, hyperpigmentation or alopecia may be observed, most commonly associated with Sertoli cell tumours (SCT). Although these signs are often associated with...

Author(s)
Holst, B. S.; Dreimanis, U.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2015, 11, 166, pp (25 July 2015)
Abstract

Background: The major types of testicular tumour in dogs are sex-cord stromal tumours, germ cell tumours, and mixed type of the germ cell-, and sex-cord stromal tumours. Objectives: The first goal of the present study was to describe the canine testicular tumour incidence in Hungary, based on the...

Author(s)
Jakab, Cs.; Szilágyi, M.
Publisher
NAKVI, Budapest, Hungary
Citation
Magyar Állatorvosok Lapja, 2017, 139, 10, pp 599-606
Abstract

An 11-year-old miniature poodle dog was presented with bilateral flank alopecia, gynecomastia, severe thrombocytopenia, and preputial edema. Based on characteristic clinical and hematological findings of hyperestrogenism and the presence of a caudal abdominal mass, a Sertoli cell tumor (SCT) was...

Author(s)
DeForge, T. L.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Veterinary Journal, 2020, 61, 9, pp 994-996
Abstract

Some canine typical Sertoli cell tumors (SCT) induce signs of hyperestrinism. However, whether variant lipid-rich SCTs have signs of hyperestrinism remains largely unknown. In the present study, an 11-year-old male Pekingese dog showed significantly elevated serum estrogen and characteristic signs...

Author(s)
Park ChulHo; Son ChangHo
Publisher
Korean Society of Veterinary Clinics, Seoul, Korea Republic
Citation
Journal of Veterinary Clinics, 2019, 36, 1, pp 78-81
Abstract

Immunohistochemical profiles of the most common canine testicular tumours, including the Leydig cell tumours, seminomas, and Sertoli cell tumours were analysed, and the results were compared with those obtained in the corresponding types of human testicular neoplasms. The expressions of vimentin,...

Author(s)
Ciaputa, R.; Nowak, M.; Madej, J. A.; Janus, I.; Górzyńska, E.; Kandefer-Gola, M.
Publisher
National Veterinary Research Institute, Puławy, Poland
Citation
Bulletin of the Veterinary Institute in Puławy, 2015, 59, 1, pp 99-106
AbstractFull Text

Testicular neoplasms are a differential diagnosis to consider in the clinical evaluation of dogs that consult for diseases of the genital tract. Its presentation is more frequent in old and cryptorchid dogs. They are considered pathologies of easy diagnosis, although their precise confirmation of...

Author(s)
Gutierrez, O. D.; Rodríguez, G. J.; Mejia, J. A. B.
Publisher
Universidad Nacional Mayor de San Marcos, Lima, Peru
Citation
Revista de Investigaciones Veterinarias del Perú (RIVEP), 2019, 30, 4, pp 1845-1850
AbstractFull Text

The aim of the present case report is to describe the clinical and pathological aspects of a MDPS case associated with cryptorchidism, Sertoli cell tumor, and pyometra in a Miniature Schnauzer dog. A 7-year-old male Miniature Schnauzer weighting 7 kg was brought to veterinary consultation due to...

Author(s)
Zambarda, T. T.; Stefani, R. Q.; Sonne, L.; Pöppl, Á. G.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2019, 47, Supplement,
Abstract

Expression of thyroid transcription factor (TTF)-1 corroborates a thyroid origin of neoplasms. Thyroglobulin and calcitonin immunohistochemistry (IHC) can distinguish between a follicular and C-cell origin of thyroid tumours, respectively. Pax8 (expressed by normal canine thyroid follicular cells)...

Author(s)
Ramos-Vara, J. A.; Frank, C. B.; DuSold, D.; Miller, M. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Comparative Pathology, 2016, 155, 4, pp 286-298

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