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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

Immunoglobulin A (IgA) is widely recognized as the important antibody isotype involved in protective responses on mucosal surfaces, where it acts primarily by effectuating immune exclusion of foreign material. Selective IgA deficiency (SIgAD) is the most common immunodeficiency disease in dogs and...

Author(s)
Ellis, J. A.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Veterinary Journal, 2019, 60, 12, pp 1305-1311
Abstract

A 1-year-old, spayed female Irish setter from California, USA was referred for evaluation of recurrent bacterial pneumonia and failure to gain weight appropriately [date not given]. At the time of referral, the dog was asymptomatic and the physical examination was unremarkable except for the dog's...

Author(s)
Norris, C. R.; Gershwin, L. J.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2003, 39, 3, pp 247-250
Abstract

Selective immunoglobulin A (IgA) deficiency is the most common primary immunodeficiency in humans and may be associated with chronic gastrointestinal disease. This observation has led to the suggestion that the high susceptibility of German shepherd dogs (GSD) to chronic enteropathies is related to ...

Author(s)
Peters, I. R.; Calvert, E. L.; Hall, E. J.; Day, M. J.
Publisher
American Society for Microbiology (ASM), Washington, USA
Citation
Clinical and Diagnostic Laboratory Immunology, 2004, 11, 5, pp 841-848
Abstract

Inherited immunodeficiencies comprising canine leucocyte adhesion deficiency (CLAD), cyclic neutropenia, Pelger-Huet syndrome, the C-3 deficiency, severe combined immunodeficiency, selective IgA deficiency, common variable immunodeficiency and lethal acrodermatitis are briefly reviewed.

Author(s)
Chełmońska-Soyta, A.
Publisher
Elamed Wydawnictwo, Katowice, Poland
Citation
Weterynaria w Praktyce, 2005, No.2, pp 18...24
Abstract

24 German Shepherd dogs were determined to have selective IgA deficiency based on quantitation of serum immunoglobulin levels by radial immune diffusion. IgA levels were either very low normal or subnormal, ranging from 0.05 to 0.20 mg/ml. Serum IgG levels were elevated in 5 dogs, normal in 17 dogs ...

Author(s)
Magne, M. L.
Citation
Journal of Veterinary Allergy and Clinical Immunology, 1996, 4, 1, pp 23-24
Abstract

Cases of selective IgA deficiency which occurred in a large breeding kennel of Beagle dogs are described. In a breeding experiment all of 5 puppies born to IgA deficient parents had low or undetectable levels of IgA. The disease is characterised by chronic, recurrent respiratory infections,...

Author(s)
Felsburg, P. J.; Glickman, L. T.; Shofer, F.; Kirkpatrick, C. E.; HoganEsch, H.
Citation
Advances in Experimental Medicine and Biology, 1987, 216B, pp 1461-1470
Abstract

The following primary immunodeficiencies are described: canine cyclic haematopoiesis (Collies), canine granulocytopathy syndrome (Irish Setters), neutrophil bacteriocidal defect (Dobermann Pinschers), Pelger-Huët anomaly (Domestic Shorthair cat and various canine breeds), Chédiak-Higashi syndrome...

Author(s)
Guilford, W. G.
Citation
Compendium on Continuing Education for the Practicing Veterinarian, 1987, 9, 6, pp 641-648, 650
Abstract

Beagles from a large breeding colony (6-7000 dogs), with a history of chronic, recurrent respiratory infections, dermatitis and otitis were examined for serum immunoglobulins, B and T lymphocyte counts, lymphocyte transformation, response to tetanus toxoid immunization, polyclonal activation of...

Author(s)
Felsburg, P. J.; Glickman, L. T.; Jezyk, P. F.
Citation
Clinical Immunology and Immunopathology, 1985, 36, 3, pp 297-305
Abstract

The authors describe 11 primary immunodeficiencies of the dog: immunodeficient dwarfism, lethal acrodermatitis, selective IgA and IgM deficiencies, transient hypogammaglobulinemia, severe combined X-linked immunodeficiency, complement C3 deficiency cyclic hematopoiesis, granulocytopathy, leukocyte...

Author(s)
Chabanne, L.; Poliak, S.; Pham Huu Trung, M.; Fournel, C.; Rigal, D.
Citation
Point Vétérinaire, 1993, 24, 150, pp 673-681

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