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Abstract

Case study of a 13-year-old female dog which displays pure red cell aplasia (PRCP) after administration of darbepoetin is reported; the dog is diagnosed chronic kidney disease (CKD) accompanied by anemia, for a blood test presents low PCV and Hb and high BUN and CR, and a urine test shows...

Author(s)
Yamaguchi, Y.; Yamaguchi, Y.
Publisher
Buneido Publishing Company Ltd, Tokyo, Japan
Citation
Journal of Veterinary Medicine, Japan, 2014, 67, 5, pp 367-370
Abstract

Background: Darbepoetin alfa (darbepoetin) is an erythropoiesis-stimulating agent used for the treatment of anemia secondary to chronic kidney disease (CKD) in dogs, but reports describing response are lacking. Hypothesis/Objectives: To evaluate the effectiveness of darbepoetin in dogs with anemia...

Author(s)
Fiocchi, E. H.; Cowgill, L. D.; Brown, D. C.; Markovich, J. E.; Tucker, S.; Labato, M. A.; Callan, M. B.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 2, pp 476-485
Abstract

Background: Precursor-targeted immune-mediated anemia (PIMA) has been suspected in dogs with nonregenerative anemia and bone marrow findings varying from erythroid hyperplasia to pure red cell aplasia. Phagocytosis of erythroid precursors/rubriphagocytosis (RP) reported in some affected dogs...

Author(s)
Lucidi, C. de A.; Rezende, C. L. E. de; Jutkowitz, L. A.; Scott, M. A.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2017, 46, 3, pp 401-415
Abstract

Pure red cell aplasia (PRCA) is a disorder that leads to a nonregenerative anemia that results from erythroid precursors failing to reach maturity in the bone marrow, whereas the numbers of mature myeloid and megakaryocytic cells remain normal. PRCA can be induced by autoimmune processes,...

Author(s)
Marchi, P. N. de; Vieira, A. N. le S.; Ribeiro, J. F. A.; Geraldes, S. S.; Ramos, P. R. R.; Melchert, A.; Guimarães-Okamoto, P. T. C.
Publisher
Elsevier Inc, Orlando, USA
Citation
Topics in Companion Animal Medicine, 2017, 32, 1, pp 44-47
Abstract

Many dogs and cats with immune-mediated haemolytic anaemia (IMHA) lack a bone marrow erythroid regenerative response. To better understand the failure of the bone marrow to respond to the anaemia, bone marrow pathology associated with non-regenerative IMHA and pure red cell aplasia (PRCA) was...

Author(s)
Weiss, D. J.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Journal of Comparative Pathology, 2008, 138, 1, pp 46-53
Abstract

A two-year-old female neutered Tibetan terrier was referred following a one-month history of lethargy, inappetence and pancytopenia, which had been poorly responsive to immunosuppressive and fluoroquinolone treatment. The dog was diagnosed with pure red cell aplasia and was found to be positive for ...

Author(s)
Wilson, H. E.; Mugford, A. R.; Humm, K. R.; Kellett-Gregory, L. M.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2013, 54, 8, pp 425-427
AbstractFull Text

The study was conducted on 12 client-owned dogs of different ages, from different races with naturally occurring CKD, including 8 with comorbidities. Determination of renal parameters was performed every week in all cases and their progress was closely correlated with the evolution of hemoglobin....

Author(s)
Vițălaru, A. B.; Ștefănescu, A.
Publisher
Facultatea de Medicină Veterinară, Timișoara, Romania
Citation
Lucrari Stiintifice - Universitatea de Stiinte Agricole a Banatului Timisoara, Medicina Veterinara, 2017, 50, 2, pp 302-305
Abstract

Objectives: To examine clinical features, laboratory test results, treatment, and outcome of dogs with pure red cell aplasia (PRCA). Design: Retrospective study. Animals: 13 dogs with severe non-regenerative anaemia and bone marrow erythroid aplasia. Procedures: Medical records of dogs determined...

Author(s)
Weiss, D. J.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2002, 221, 1, pp 93-95
Abstract

Blood transfusion has been described in ferrets as a treatment for oestrus-associated anaemia and as a life-saving therapy following trauma, iatrogenic (usually surgery-induced) anaemia, autoimmune haemolytic anaemia and pure red cell aplasia. Although blood banking is a common method for storage...

Author(s)
Pignon, C.; Donnelly, T. M.; Todeschini, C.; Deschamps, J. Y.; Roux, F. A.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record, 2014, 174, 11, pp 277
AbstractFull Text

Aplastic bone marrow (also known as aplastic anemia) is relatively rare in small animals. It is characterized by pancytopenia in the peripheral blood and a three linage bone marrow hypoplasia (erythroid, myeloid and megakaryocytic), resulting in hematopoietic cells replacement by fat tissue....

Author(s)
Moraes, L. F.; Takahira, R. K.
Publisher
Universidade do Estado de Santa Catarina (UDESC), Santa Catarina, Brazil
Citation
Revista de Ciencias Agroveterinarias , 2010, 9, 1, pp 99-108

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