This article discusses the clinical signs, diagnosis, treatment and prognosis of cyclotrimethylenetrinitramine (also known as cyclonite or C-4) in military working dogs. A case of C-4 ingestion in a 2-year-old military working dog in Afghanistan [date not given] is also included.

Objective - To describe the clinical manifestations following cyclonite (C-4) plastic explosive ingestion in a dog. Case Summary - A 2-year-old male castrated Labrador working dog weighing 35 kg was presented for seizures shortly after ingestion of C-4. The dog was successfully treated for the...

A 12-year-old male German Shepherd dog suspected of having ingested minute quantities of plastic explosive type 4 (PE4 containing cyclonite) was presented with congested mucous membranes, a fever, an increased pulse rate, hyperventilation, hypersensitivity and mild convulsions. Gastric lavage was...

In retrieving some plastic explosive (PE4) containing cyclonite, a police dog bit into the wrapper and swallowed some of the contents. The next morning it was unsteady on its feet, salivating profusely, and very nervous; it then had a violent epileptiform convulsion and vomited. During recovery...