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Abstract

Objective: To report the incidence of adverse events during euthanasia of client-owned dogs administered either intravenous pentobarbital/phenytoin (PP) or PP after propofol delivery. Design/Setting: Prospective, observational, multi-site study. Animals: Four hundred thirty-six dogs undergoing...

Author(s)
Bullock, J. M.; Lanaux, T. M.; Shmalberg, J. W.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Emergency and Critical Care, 2019, 29, 2, pp 161-165
Abstract

The purpose of this study was to determine the pharmacokinetics of phenytoin, theophylline, and diazepam in six healthy Greyhound dogs. Additionally, the pharmacokinetics of the diazepam metabolites, oxazepam and nordiazepam, after diazepam administration was determined. Phenytoin sodium (12...

Author(s)
KuKanich, B.; Nauss, J. L.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2012, 35, 3, pp 275-281
Abstract

The present work was designed to evaluate the effect of some commonly used herbs viz. garden cress (Lepidium sativum), black seed (Nigella sativa) and fenugreek (Trigonella foenum-graceum) on the disposition of phenytoin after oral administration in a dog model. Phenytoin was given orally at a dose ...

Author(s)
Alkharfy, K. M.; Al-Jenoobi, F. I.; Al-Mohizea, A. M.; Al-Suwayeh, S. A.; Khan, R. M. A.; Ajaz Ahmad
Publisher
Wiley-Blackwell, Chichester, UK
Citation
Phytotherapy Research, 2013, 27, 12, pp 1800-1804
Abstract

The pharmacoresistance to antiepileptic drugs (AEDs) remains a major unsolved therapeutic need. The overexpression of multidrug transporters, as the P-glycoprotein (P-gp), at the level of the blood-brain barrier of epileptic patients has been suggested as a key mechanism underlying the refractory...

Author(s)
Ferreira, A.; Rodrigues, M.; Fortuna, A.; Falcão, A.; Alves, G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Food Research International, 2018, 103, pp 110-120
Abstract

It was attended a Labrador female dog of 9 years presenting convulsive crisis in intervals of 30 minutes (status epilepticus) due to a atropine intoxication. The treatment was established with oxygen, Ringer-lactate IV infusion, neostigmine in the dose of 0.05 mg/kg IM as antidote of the atropine...

Author(s)
Andrade, S. F.; Silva, D. A.; Vilella, G. T. A.
Publisher
Universidade Federal Rural do Semi-Árido (UFERSA), Mossoro, Brazil
Citation
Acta Veterinaria Brasilica, 2013, 7, Suppl. 1, pp 389-391
Abstract

Objective - To determine whether antiepileptic drugs (AEDs) are substrates for canine P-glycoprotein (P-gp). Sample Population - OS2.4/Doxo cells (canine osteosarcoma cells induced via exposure to doxorubicin to highly express P-gp). Procedures - Competitive inhibition of rhodamine 123 efflux from...

Author(s)
West, C. L.; Mealey, K. L.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2007, 68, 10, pp 1106-1110
AbstractFull Text

The prevalence of cardiac arrhythmias was studied in the canine population of 20,000 reported during a period of four years to hospital. The prevalence of arrhythmias was recorded as 3.04%. The arrhythmias were grouped into three categories as sinus arrhythmia, abnormalities of impulse formation...

Author(s)
Varshney, J. P.; Prajwalita Sutaria; Deshmukh, V. V.; Chaudhary, P. S.
Publisher
Intas Pharmaceuticals Ltd, Ahmedabad, India
Citation
Intas Polivet, 2013, 14, 1, pp 129-136
Abstract

A nine-year-old male Maltese dog was presented with an eight-month history of inspiratory stridor leading to exertional dyspnoea and cyanosis. Myokymic contractions in the palatolingual muscles were noticed and confirmed by electromyography. Brain computer tomography-scan showed ventricular...

Author(s)
Vanhaesebrouck, A. E.; Bhatti, S. F.; Bavegems, V.; Gielen, I. M.; Soens, I. van; Vercauteren, G.; Polis, I.; Ham, L. M. van
Publisher
Blackwell Publishing Ltd, Oxford, UK
Citation
Journal of Small Animal Practice, 2010, 51, 3, pp 173-175
Abstract

A treatment protocol is described, based on early aggressive intervention. The use of imepitoin, phenobarbital, potassium bromide, and phenytoin by Dutch veterinarians is outlined.

Author(s)
Overduin, L.; Mandigers, P. J. J.
Publisher
Koninklijke Nederlandse Maatschappij voor Diergeneeskunde, Houten, Netherlands
Citation
Tijdschrift voor Diergeneeskunde, 2015, 140, 9, pp 23-30
CABI Book Chapter Info
Cover for Pathophysiology and management of status epilepticus.

The aetiology, diagnosis, pathophysiology and management of status epilepticus in dogs and cats are presented.

Author(s)
Platt, S.
ISBN
2014 CABI (H ISBN 9781780641096)
Type
Book chapter

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