Objective: To report a case series of canine naproxen overdoses successfully treated with intravenous lipid emulsion therapy (IVLE). Series Summary Three dogs were presented for acute ingestion of naproxen and were treated with IVLE. Baseline and post treatment serum naproxen concentrations were...

Background: Therapeutic plasma exchange (TPE) is gaining popularity for the management of nonsteroidal anti-inflammatory drug (NSAID) overdose in dogs. Hypothesis/Objectives Describe a population of dogs treated with TPE for NSAID overdose. Animals Sixty-two dogs with NSAID overdose treated with...

The kidney has an essential role in maintaining normal physiological functions but it can be affected by various drugs and chemicals. A common seasonal cause of renal failure in cats is ingestion of antifreeze containing ethylene glycol. It is not the ethylene glycol itself which causes renal...

These proceedings contain 12 papers on the following topics: suspected air embolism in the horse; general anesthesia of an adult pregnant cattle - a case report; corneal ulcer in elephants - sedation and local anesthesia on the eye; anesthesia management for dogs and cats in Lower Saxony; effect of ...

This article discusses the pharmacokinetics, mechanism of action, toxicity, clinical aspects, adverse effects, decontamination, monitoring and treatment, and prognosis in dogs affected with naproxen, a non-steroidal antiinflammatory agent, toxicosis.

The kidney has an essential role in maintaining normal physiological functions but it can be affected by various drugs and chemicals. A common seasonal cause of renal failure in cats is ingestion of antifreeze containing ethylene glycol. It is not the ethylene glycol itself which causes renal...

Naproxen, a nonsteroidal anti-inflammatory drug, induced gastric ulceration and bleeding in a dog. Clinical signs included vomiting, anaemia, melena, and weakness. The dog responded to a blood transfusion and supportive treatment (lactated Ringer's solution with added K⁺ and B vitamins, an antacid, ...

Toxicosis is described in a puppy that had been given 220 mg of naproxen (Alleve) over a 4-day period. Clinical signs included melaena, lethargy and vomiting. Treatment included blood transfusion (to treat anaemia), administration of gastroprotective medications and supportive care.

The unsuitability for dogs of this drug, prepared for human use, is shown by reference to 3 case reports. The animals showed clinical signs including vomiting, diarrhoea, anaemia, oedema, an increased tendency to bleed, fatigue, incoordination and staggering. Liver enzyme levels were raised and...