In order to study the function of canine CD19 and the diagnosis and treatment of canine B-cell lymphoma, the BALB/c mice was immunized with purified recombinant protein CD19-mFc expressed in CHO cells as immunogens and the recombinant protein CD19-HSA expressed in 293 cells was used as the...
Author(s)
Du MengMeng; Wang XiaoJuan; He ShuaiJie; Hu HuanXin; Chen ZhenZhen; Tan JingMing; Chen YuMing; Hu PengHui; Tan FeiFei; Tian KeGong
Publisher
Chinese Veterinary Science, Lanzhou, China
Citation
Chinese Veterinary Science / Zhongguo Shouyi Kexue, 2022, 52, 4, pp 458-465
This proceedings contain 25 topics on whole genome sequencing to explore genetic risk factors in canine myxomatous mitral valve disease, evaluation of radiographic predictors of left heart enlargement in dogs, short-term outcome of a prospective study of diet-associated dilated cardiomyopathy (DCM) ...
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 6, pp 2817-2989
Multiple myeloma (MM) is a tumor of plasma cells representing approximately 1% of all canine tumors. Clinical evident bleeding is often referred to as the main finding. The aim of the study was to evaluate the occurrence of clinical bleedings in dogs with MM and its prognostic implications compared ...
Author(s)
Caldin, M.; Campigli, M.; Zoia, A.; Zanella, A.; Bertolini, G.; Furlanello, T.; Lubas, G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2019, 125, pp 305-308
Background: Densitometric quantification of myeloma paraproteins (M-proteins) is used to monitor secretory myeloma related disorders in humans and dogs. The previous work in dogs used agarose gel electrophoresis (AGE) but did not establish if other methods of serum protein electrophoresis, such as...
Author(s)
Jeffries, C. M.; Harris, R. A.; Ashton, L.; Moore, A. R.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2021, 50, 4, pp 543-550
Background: Current recommendations for monitoring disease progression and response to treatment in humans with multiple myeloma include evaluation of serum paraprotein (M-protein) concentration. Densitometry, species-specific radial immunodiffusion (RID) and ELISA methods can be used to quantify...
Author(s)
Moore, A. R.; Harris, A.; Jeffries, C.; Avery, P. R.; Vickery, K.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 35, 1, pp 442-450
Background: The diagnostic performance of routine electrophoresis (agarose gel electrophoresis [AGE] and capillary zone electrophoresis [CZE]) and species-specific immunofixation (IF) for the detection of immunoglobulin paraproteins (M-proteins) and diagnosis of secretory myeloma-related disorders...
Author(s)
Moore, A. R.; Harris, R. A.; Jeffries, C.; Ashton, L.; Avery, P. R.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2021, 50, 2, pp 249-258
Routine electrophoresis [agarose gel electrphoresis (AGE) and capillary zone eletrophoresis (CZE) and species-specific immunofixation (IF) can be used alone or in combination to detect immunoglobulin paraprotein (M-protein) and diagnose secretory myeloma-related disorders (sMRD). Objective: We...
Author(s)
Moore, A. R.; Harris, R. A.; Jeffries, C.; Avery, P. R.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2021, 50, 2, pp 240-248
An 11-year-old male Cocker Spaniel was presented with acute onset of apathy, polyuria and polydipsia. Blood examination showed hypoalbuminemia and hyperglobulinemia, while electrophoresis revealed monoclonal gammopathy. Subsequent tests showed glycosuria, proteinuria, a positive serology test for ...
Author(s)
Turna, H.; Tothova, C.; Kozar, M.; Valencakova-Agyagosova, A.; Figurova, M.; Grelova, S.; Takacova, M.; Svoboda, M.
Publisher
Fakultet Veterinarske Medicine, Univerziteta u Beogradu, Belgrade, Serbia
Citation
Acta Veterinaria (Beograd), 2022, 72, 2, pp 276-286
Considering the strong immunogenicity of the Dal antigen, and that > 98% of dogs, including blood donors, are Dal-positive, finding compatible blood for a previously transfused Dal-negative patient may be challenging. This is exacerbated by limited access to typing reagents, which currently rely on ...
Author(s)
Mesa, C. L. C.; Gottschalk, M.; Lacouture, S.; Blais, M. C.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2022, 254,
Objectives: To further characterise solitary osseous plasmacytoma in dogs, an extremely rare disease. To describe diagnosis, disease progression and treatment outcomes in dogs with solitary osseous plasmacytoma. Materials and Methods: Retrospective review of dogs with solitary osseous plasmacytomas ...
Author(s)
Reising, A. J.; Donnelly, L. L.; Flesner, B. K.; Maitz, C. A.; Bryan, J. N.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2021, 62, 12, pp 1114-1121