A 4 mo old spayed female mixed-breed dog was presented for focal lower motor neuron signs of the right forelimb and marked hyperesthesia on axillary palpation. Her signs progressed rapidly over the following days to diffuse lower motor neuron signs in all limbs and a seizure. MRI demonstrated a...
Author(s)
Green, L.; Cook, L.; Martinez, M.; Green, E.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2020, 56, 2, pp 127-132
A two-year-old local Dog weight 13 kg was examined at the Veterinary Internal Medicine Laboratory, Faculty of Veterinary Medicine, Udayana University. The examination shown only thoracic limbs supported his walk and short steps. This shown clinical signs of Paraplegia and urine incontinence....
Author(s)
Marmanto, T. S.; Soma, I. G.; Suartha, I. N.
Publisher
Fakultas Kedokteran Hewan, Universitas Udayana, Denpasar, Indonesia
Citation
Indonesia Medicus Veterinus, 2020, 9, 1, pp 28-36
Canine degenerative myelopathy (DM) is an adult-onset, chronic, progressive neurodegenerative disease reported in multiple canine breeds, including the German Shepherd Dog (GSD). Clinical signs include progressive motor neuron paralysis, which begins in the pelvic limbs and eventually leads to...
Author(s)
Maki, S.; Islam, M. S.; Itoh, T.; Nurimoto, M.; Yabuki, A.; Furusawa, Y.; Kamishina, H.; Kobatake, Y.; Rakib, T. M.; Tacharina, M. R.; Yamato, O.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2022, 12, 13,
Canine degenerative myelopathy (DM) is a late-onset, progressive, neurodegenerative dis - order with a fatal outcome, occurring in a vast number of dog breeds. Most dogs are at least eight years of age when they begin to show clinical signs, starting with general proprioceptive ataxia in the hind...
Author(s)
Boeykens, F.; Peelman, L.; Bhatti, S.; Broeckx, B. J. G.
Publisher
Faculty of Veterinary Medicine, University of Ghent, Merelbeke, Belgium
Citation
Vlaams Diergeneeskundig Tijdschrift, 2020, 89, 5, pp 253-261
Motor unit number estimation (MUNE) is an electrophysiological technique to assess the number of motor units innervating a single muscle or muscle group of interest. It may quantify axonal loss in any disease involving injury or degeneration of ventral horn cells or motor axons. Since MUNE has...
Author(s)
Kauder, J.; Petri, S.; Tipold, A.; Stein, V. M.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2015, 2, November, pp 53
The purpose of the current review is to summarize data regarding hereditary myelopathies in dogs. Canine degenerative myelopathy (DM) is a progressive disease prevalent in senior (≥8 years old), large breed-dogs, predominating in German shepherd dog. Neurolocalization indicates a thoracolumbar,...
Author(s)
Baka, R.; Polizopoulou, Z.
Publisher
Hellenic Veterinary Medical Society, Athens, Greece
Citation
Journal of the Hellenic Veterinary Medical Society, 2021, 72, 1, pp 2583-2594
Canine degenerative myelopathy (CDM) is an autosomal recessive disease characterized by progressive ascending degeneration of the spinal cord. The clinical features of CDM include progressive, asymmetric upper motor neuron paraparesis and lack of paraspinal pain. According to the literature, there...
Author(s)
Cocostîrc, V.; Paștiu, A. I.; Pusta, D.
Publisher
Facultatea de Medicina Veterinara, Timisoara, Romania
Citation
Lucrari Stiintifice - Universitatea de Stiinte Agricole a Banatului Timisoara, Medicina Veterinara, 2022, 55, 1, pp 5-15
We investigated the expression of microtubule-associated protein 1 light chain 3 (LC3) protein in the cerebellums of dogs infected with canine distemper virus (CDV) using immunohistochemistry to detect autophagy. The cerebellums of 20 dogs infected with CDV were used. Specimens showing...
Author(s)
Kabak, Y. B.; Sozmen, M.; Yarİm, M.; Guvenc, T.; Karayİgİt, M. O.; Gulbahar, M. Y.
Publisher
Taylor & Francis, Philadelphia, USA
Citation
Biotechnic & Histochemistry, 2015, 90, 8, pp 601-607
OBJECTIVE: To determine values of F-wave parameters for the tibial nerve in clinically normal Miniature Dachshunds and those with thoracolumbar intervertebral disk herniation (IVDH). ANIMALS: 53 Miniature Dachshunds (10 clinically normal and 43 with various clinical grades of thoracolumbar IVDH)....
Author(s)
Okuno, S.; Orito, K.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2020, 81, 5, pp 422-427
Diseases presenting with lower motor neuron (LMN) signs are frequently seen in small animal veterinary practice in Australia. In addition to the most common causes of LMN disease seen world-wide, such as idiopathic polyradiculoneuritis and myasthenia gravis, there are several conditions presenting...
Author(s)
Herndon, A. M.; Thompson, A. T.; Mack, C.
Publisher
Hindawi, London, UK
Citation
Journal of Veterinary Medicine, 2018, No.2018, pp Article ID 1018230