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Abstract

A 9 mo old female intact golden retriever presented for evaluation of chronic lethargy and decreased appetite. The serum biochemistry profile revealed increased liver enzymes consistent with a mixed hepatocellular and cholestatic pattern. A multiphase computed tomography angiography was performed...

Author(s)
Hostnik, E. T.; Parker, V. J.; Cullen, J. M.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2019, 55, 2, pp e552-03
Abstract

Hepatic progenitor cells (HPCs) are an adult stem cell compartment in the liver that contributes to liver regeneration when replication of mature hepatocytes is insufficient. In this study, laser microdissection was used to isolate HPC niches from the livers of healthy dogs and dogs with lobular ...

Author(s)
Kruitwagen, H. S.; Spee, B.; Viebahn, C. S.; Venema, H. B.; Penning, L. C.; Grinwis, G. C. M.; Favier, R. P.; Ingh, T. S. G. A. M. van den; Rothuizen, J.; Schotanus, B. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2014, 201, 3, pp 345-352
AbstractFull Text

Lobular hepatitis dissecans is an inflammatory disorder of idiopathic cause, characterized as chronic hepatitis. It develops in the young liver after recurrent lesions to the organ, has an unfavorable prognosis, with the shortest survival within liver diseases. A seven-month Golden Retriever male ...

Author(s)
Alberti, T. dos S.; Stumm, G. K. F.; Zamboni, R.; Rosa, C. S. da; Bonel, J.
Publisher
Universidade Estadual do Ceará, Faculdade de Veterinaria, Ceará, Brazil
Citation
Ciência Animal, 2018, 28, 2, pp 113-119
Abstract

Background: American Cocker Spaniels are predisposed to chronic hepatitis. Objective: To describe the clinical and histological features of chronic hepatitis in Japanese American Cocker Spaniels. Animals: Thirteen cases examined from 2003 to 2009. Methods: Retrospective study. Medical records were...

Author(s)
Kanemoto, H.; Sakai, M.; Sakamoto, Y.; Spee, B.; Ingh, T. S. G. A. M. van den; Schotanus, B. A.; Ohno, K.; Rothuizen, J.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2013, 27, 5, pp 1041-1048
Abstract

Background: The liver has a large regenerative capacity. Hepatocytes can replicate and regenerate a diseased liver. However, as is the case in severe liver diseases, this replication may become insufficient or exhausted and hepatic progenitor cells (HPCs) can be activated in an attempt to restore ...

Author(s)
Schotanus, B. A.; Kruitwagen, H. S.; Ingh, T. S. van den; Wolferen, M. E. van; Rothuizen, J.; Penning, L. C.; Spee, B.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2014, 10, 309, pp (31 December 2014)
Abstract

Histological and immunohistochemical evaluations of lobular dissecting hepatitis (LDH) were performed in nine American cocker spaniel dogs. Histological examination showed diffuse fibrosis with weak inflammatory reaction of extensive neutrophils, macrophages, lymphocytes and plasma cells....

Author(s)
Mizooku, H.; Kagawa, Y.; Matsuda, K.; Okamoto, M.; Taniyama, H.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2013, 75, 5, pp 597-603
AbstractFull Text

Hepatic lipogranulomas are poorly defined lesions and have an undetermined significance and etiology. They are often found in the hepatic parenchyma of dogs, and are associated with previous hepatocyte death and circulatory disorders. The aim of the present study was to determine the correlation...

Author(s)
Nagy, A. L.; Bolfa, P.; Taulescu, M.; Tabaran, F.; Catoi, C.; Gal, A. F.; Catoi, A. F.
Publisher
University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania
Citation
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine , 2013, 70, 1, pp 97-103
Abstract

During fibrosis, the extracellular matrix (ECM) is continuously remodeled and increases in volume due to the production of various proteins. We studied the distribution of tenascin-C (TN-C) and the correlation of TN-C with the necro-inflammatory activity and expression of alpha-smooth muscle actin...

Author(s)
Mekonnen, G. A.; Ijzer, J.; Nederbragt, H.
Publisher
American College of Veterinary Pathologists Inc., Lawrence, USA
Citation
Veterinary Pathology, 2007, 44, 6, pp 803-813
Abstract

Background: Little is known about etiology, disease progression, treatment outcome, survival time, and factors affecting prognosis in dogs with primary hepatitis (PH). Objectives: To review retrospectively different forms of hepatitis in a referral population, by the World Small Animal Veterinary...

Author(s)
Poldervaart, J. H.; Favier, R. P.; Penning, L. C.; Ingh, T. S. G. A. M. van den; Rothuizen, J.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Journal of Veterinary Internal Medicine, 2009, 23, 1, pp 72-80
AbstractFull Text

Two Golden Retriever dogs genetically unrelated and with different owners were referred to the Veterinary Medical Teaching Hospital of the Universidade Luterana do Brasil (ULBRA) [date not given]. The first case was a female aged 17 months and the second, brought to examination one year later, was...

Author(s)
Argenta, F. F.; Hobbhahn, S.; Witz, M. I.; Fallavena, L. C. B.; Esmeraldino, A. T.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2017, 45, Supplement, pp 216

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