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AbstractFull Text

Background: The liver plays a variety of essential biochemical functions such as the metabolism of carbohydrates, proteins, lipids and vitamins, the maintenance of blood glucose and bile acids synthesis. Hepatic insufficiency occurs when 70 to 80% of the functional liver mass is committed the liver ...

Author(s)
Mottin, T. da S.; Pinto, L. A. T.; Pöppl, A. G.; Macedo, A. S.; Dal-Bó, Í. dos S.; Bandinelli, M. B.; Gerardi, D. G.; Driemeier, D.; Beck, C. A. de C.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2013, 41, Suppl. 1, pp 30
Abstract

Of 71 West Highland White Terriers, 27 had a histologically normal liver and a copper concentration measured by atomic absorption comparable to that of crossbred controls; 44 terriers had hepatic copper concentrations up to 22 times the mean copper concentration found in clinically normal controls. ...

Author(s)
Thornburg, L. P.; Shaw, D.; Dolan, M.; Raisbeck, M.; Crawford, S.; Dennis, G. L.; Olwin, D. B.
Citation
Veterinary Pathology, 1986, 23, 2, pp 148-154
Abstract

Concurrent hepatic copper toxicosis and Fanconi's syndrome was reported in a 3-year-old male, castrated, West Highland White Terrier [USA, date not given]. The dog had a one week history of intermittent vomiting, polyuria, polydypsia, progressive anorexia and lethargy. On physical examination, the ...

Author(s)
Hill, T. L.; Breitschwerdt, E. B.; Cecere, T.; Vaden, S.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Journal of Veterinary Internal Medicine, 2008, 22, 1, pp 219-222
Abstract

Histomorphologic, histochemical, and atomic absorption analysis studies were performed on liver tissue from 623 healthy purebred and mixed-breed dogs (including 395 West Highland White Terriers, and 149 Bedlington Terriers) to assess the range of hepatic copper concentrations that were found....

Author(s)
Thornburg, L. P.; Rottinghaus, G.; McGowan, M.; Kupka, K.; Crawford, S.; Forbes, S.
Citation
Veterinary Pathology, 1990, 27, 2, pp 81-88
Abstract

A liver disease registry started in 1980 at the University of Missouri contains details of 750 dogs and 200 cats. Evidence for hereditary copper toxicosis is conclusive for West Highland White Terriers and Dobermann Pinschers and strong for Labrador Retrievers and Cocker Spaniels. Several other...

Author(s)
Thornburg, L. P.; Polley, D.; Dimmitt, R.
Citation
Canine Practice, 1984, 11, 5, pp 36-39
Abstract

A general account of this hereditary disease, caused by the accumulation of copper in the liver, is followed by 4 case reports (2 West Highland White Terriers, 1 Bedlington Terrier and 1 Poodle). Emphasis is placed on the histological findings.

Author(s)
Nielsen, O. L.; Flagstad, A.; Larsen, S.; Friis, C.
Citation
Dansk Veterinærtidsskrift, 1991, 74, 6, pp 205-209

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