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Abstract

Thyroid cancer is the most common endocrine malignancy in dogs. Dogs and humans are similar in the spontaneous development of thyroid cancer and metastasis to lungs; however, thyroid cancer has a higher incidence of metastasis in dogs. This study developed a preclinical nude mouse model of canine...

Author(s)
Hassan, B. B.; Altstadt, L. A.; Dirksen, W. P.; Elshafae, S. M.; Rosol, T. J.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Veterinary Pathology, 2020, 57, 2, pp 227-240
Abstract

Renal adenocarcinoma is the most common primary tumour of the canine kidney. A typical renal tumour is a consequence of metastatic tumour whereas primary tumours are rare. By the time clinical signs are apparent, the primary tumour has often reached considerable size and may have metastasized....

Author(s)
Nyyssönen, K.; Vapaavuori, O.
Publisher
Suomen Eläinlääkäriliitto, Helsinki, Finland
Citation
Suomen Eläinlääkärilehti, 2019, 125, 5, pp 255-260
Abstract

The prognostic significance of histologic and clinical features was evaluated in a retrospective study of 70 dogs treated with nephrectomy for renal cell carcinoma. Dogs presenting with hematuria and cachexia had significantly decreased overall and tumor-specific survival. Mitotic index (MI),...

Author(s)
Edmondson, E. F.; Hess, A. M.; Powers, B. E.
Publisher
American College of Veterinary Pathologists Inc., Lawrence, USA
Citation
Veterinary Pathology, 2015, 52, 2, pp 260-268
Abstract

OBJECTIVE: To describe cytologic characteristics of renal fine-needle aspirate (FNA) samples from dogs, evaluate proportions of cytologic specimens deemed adequate for interpretation (diagnostic yield), assess diagnostic utility of cytologic examination for neoplastic and nonneoplastic diseases,...

Author(s)
McAloney, C. A.; Sharkey, L. C.; Feeney, D. A.; Seelig, D. M.; Avery, A. C.; Jessen, C. R.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2018, 252, 10, pp 1247-1256
Abstract

OBJECTIVES: To measure serum and urine neutrophil gelatinase-associated lipocalin (NGAL) concentrations in healthy dogs and dogs with chronic kidney disease, neoplasia and endotoxaemia. METHODS: Serum and urine NGAL concentrations were measured in 42 healthy dogs, 11 dogs with chronic kidney...

Author(s)
Cobrin, A. R.; Blois, S. L.; Abrams-Ogg, A. C. G.; Kruth, S. A.; Dewey, C.; Holowaychuk, M. K.; Gauthier, V.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2016, 57, 6, pp 291-298
Abstract

In veterinary medicine, abdominal ultrasonography is used to rank the differential diagnosis of renal lesions. However, a conventional sonographic examination may show nonspecific findings. The purpose of this study was to assess the computed tomography (CT) findings of canine renal tumors,...

Author(s)
Tanaka, T.; Akiyoshi, H.; Nishida, H.; Mie, K.; Lin LeeShuan; Iimori, Y.; Okamoto, M.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 11, pp e0225211
AbstractFull Text

Podoplanin (PDPN) is a type I transmembrane sialoglycoprotein with O-glycosylation and a high content of sialic acid. PDPN has been reported to be expressed in various human tumors and promote tumor progression, epithelial-mesenchymal transition, and distant metastasis. PDPN is also expressed in...

Author(s)
Kiname, K.; Yoshimoto, S.; Kato, D.; Tsuboi, M.; Tanaka, Y.; Yoshitake, R.; Eto, S.; Shinada, M.; Chambers, J.; Saeki, K.; Kinoshita, R.; Yamada, S.; Uchida, K.; Kaneko, M. K.; Nishimura, R.; Kato, Y.; Nakagawa, T.
Publisher
Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
Citation
Japanese Journal of Veterinary Research, 2019, 67, 1, pp 25-34
Abstract

Background: Toceranib phosphate (TOC) could be made widely available for treating tumors in dogs if evidence shows that TOC inhibits recurrence after surgery. Objectives: To investigate how postoperative adjuvant treatment with TOC modulates the tumor microenvironment (TME), by assessing effects on ...

Author(s)
Yamazaki, H.; Tanaka, T.; Mie, K.; Nishida, H.; Miura, N.; Akiyoshi, H.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 3, pp 1272-1281
Abstract

Background: Renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a rare inherited cancer syndrome observed predominantly in the German shepherd dog breed, known to be associated with dominant autosomal transmission of mutation H255R of the encoding folliculin gene (FLCN). The syndrome...

Author(s)
Ciccarelli, S.; Bello, A. di; Valastro, C.; Leo, C.; Lenoci, D.; Rana, E.; Franchini, D.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2019, 30, 2, pp 174-e54
Abstract

The skin is an organ with a wide variety of functions, being composed of different cell types and lying in constant exposure to the environment. Because of its complex structure and constant exposure, a huge variety of tumors can affect this organ. Due to its high rate of cell renewal, the chances...

Author(s)
Maia, A. R. S.; Magalhães, F. F. de; Vasconcelos, R. H.; Bezerra, W. G. A.; Costa, P. P. C.
Publisher
Federal University of Ceará, Fortaleza, Brazil
Citation
Revista Brasileira de Higiene e Sanidade Animal, 2017, 11, 4, pp 433-447

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