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Abstract

Cyclooxygenase (COX) isoforms-1 and -2 have been extensively investigated in cancer. Although COX-2 is the isoform most studied and has been described in several malignancies associated with histologic criteria of malignancy and worse prognosis, COX-1 has also been linked to some forms of cancer....

Author(s)
Gregório, H.; Magalhães, T. R.; Pires, I.; Prada, J.; Carvalho, M. I.; Queiroga, F. L.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Medicine and Science, 2021, 7, 4, pp 1107-1119
Abstract

Thyroid cancer is the most common endocrine malignancy in dogs. Dogs and humans are similar in the spontaneous development of thyroid cancer and metastasis to lungs; however, thyroid cancer has a higher incidence of metastasis in dogs. This study developed a preclinical nude mouse model of canine...

Author(s)
Hassan, B. B.; Altstadt, L. A.; Dirksen, W. P.; Elshafae, S. M.; Rosol, T. J.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Veterinary Pathology, 2020, 57, 2, pp 227-240
Abstract

Renal adenocarcinoma is the most common primary tumour of the canine kidney. A typical renal tumour is a consequence of metastatic tumour whereas primary tumours are rare. By the time clinical signs are apparent, the primary tumour has often reached considerable size and may have metastasized....

Author(s)
Nyyssönen, K.; Vapaavuori, O.
Publisher
Suomen Eläinlääkäriliitto, Helsinki, Finland
Citation
Suomen Eläinlääkärilehti, 2019, 125, 5, pp 255-260
Abstract

Canine prostatic adenocarcinoma is an aggressive malignancy characterized by rapid growth, local invasiveness, and early metastatic spread. Metastases of prostatic cancer are generally diffuse at the time of diagnosis due to hematogenous or lymphatic spread and by direct exfoliation of neoplastic...

Author(s)
Maria, F. M. di; Annoni, M.; Roccabianca, P.; Antoniazzi, E.; Bertazzolo, W.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2020, 49, 3, pp 459-464
Abstract

OBJECTIVE: To describe cytologic characteristics of renal fine-needle aspirate (FNA) samples from dogs, evaluate proportions of cytologic specimens deemed adequate for interpretation (diagnostic yield), assess diagnostic utility of cytologic examination for neoplastic and nonneoplastic diseases,...

Author(s)
McAloney, C. A.; Sharkey, L. C.; Feeney, D. A.; Seelig, D. M.; Avery, A. C.; Jessen, C. R.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2018, 252, 10, pp 1247-1256
Abstract

OBJECTIVES: To measure serum and urine neutrophil gelatinase-associated lipocalin (NGAL) concentrations in healthy dogs and dogs with chronic kidney disease, neoplasia and endotoxaemia. METHODS: Serum and urine NGAL concentrations were measured in 42 healthy dogs, 11 dogs with chronic kidney...

Author(s)
Cobrin, A. R.; Blois, S. L.; Abrams-Ogg, A. C. G.; Kruth, S. A.; Dewey, C.; Holowaychuk, M. K.; Gauthier, V.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2016, 57, 6, pp 291-298
Abstract

The prognostic significance of histologic and clinical features was evaluated in a retrospective study of 70 dogs treated with nephrectomy for renal cell carcinoma. Dogs presenting with hematuria and cachexia had significantly decreased overall and tumor-specific survival. Mitotic index (MI),...

Author(s)
Edmondson, E. F.; Hess, A. M.; Powers, B. E.
Publisher
American College of Veterinary Pathologists Inc., Lawrence, USA
Citation
Veterinary Pathology, 2015, 52, 2, pp 260-268
AbstractFull Text

Renal carcinoma (CR) is a malignant neoplasm originating from the renal tubular epithelium. This type of cancer is rare and usually affects middle-aged male dogs. Clinical signs are nonspecific and may resemble other diseases and this makes the diagnosis made by imaging (ultrasound and X-ray),...

Author(s)
Dourado, B. S. M.; Biaggi, A.; Roque, B.; Almeida, F. M. de; Shigeo, R.; Medina, A. M.
Publisher
Pubvet, Maringá, Brazil
Citation
PUBVET, 2021, 15, 4,
Abstract

In veterinary medicine, abdominal ultrasonography is used to rank the differential diagnosis of renal lesions. However, a conventional sonographic examination may show nonspecific findings. The purpose of this study was to assess the computed tomography (CT) findings of canine renal tumors,...

Author(s)
Tanaka, T.; Akiyoshi, H.; Nishida, H.; Mie, K.; Lin LeeShuan; Iimori, Y.; Okamoto, M.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 11, pp e0225211
Abstract

Background: Toceranib phosphate (TOC) could be made widely available for treating tumors in dogs if evidence shows that TOC inhibits recurrence after surgery. Objectives: To investigate how postoperative adjuvant treatment with TOC modulates the tumor microenvironment (TME), by assessing effects on ...

Author(s)
Yamazaki, H.; Tanaka, T.; Mie, K.; Nishida, H.; Miura, N.; Akiyoshi, H.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 3, pp 1272-1281

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