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Abstract

Background: Mammary gland tumor is the most common spontaneous tumor in intact female dogs, and its poor prognosis remains a clinical challenge. Ivermectin, a well-known anti-parasitic agent, has been implicated as a potential anticancer agent in various types of human cancer. However, there are no ...

Author(s)
Diao HongXiu; Cheng Nan; Zhao Ying; Xu HuiHao; Dong HaoDi; Thamm, D. H.; Zhang Di; Lin DeGui
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2019, 15, 276, pp (2 August 2019)
Abstract

Vincristine is the first-line drug for the chemotherapy of canine transmissible venereal tumor (CTVT). Drug resistance is related to tumor cyto-morphological patterns of CTVT. There are anti-cancer properties of ivermectin, thus, a combination of ivermectin and vincristine could be an effective...

Author(s)
Bulhosa, L. F.; Estrela-Lima, A.; Solcà, M. da S.; Gonçalves, G. S. D.; Larangeira, D. F.; Pinho, F. A. de; Barrouin-Melo, S. M.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Animal Reproduction Science, 2020, 216,
Abstract

Ivermectin (IV) is a macrocyclic lactone commonly used in the treatment of human parasites and as endectocidal in veterinary medicine, but evidence in both in vitro and in vivo models indicates that ivermectin may exert antitumor effects in isolation or synergistically. Thus, the present study...

Author(s)
Silva, J. C. S.
Publisher
Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, Brazil
Citation
Avaliação do perfil citotóxico da associação de Doxorrubicina com Ivermectina em um modelo celular de melanoma canino, 2019, pp 79 pp.
Abstract

Twenty-two dogs diagnosed with canine heartworm disease (HWD) were classified into four groups (Class 1 [11 dogs], Class 2 [5 dogs], Class 3 [5 dogs], and Class 4 [1 dog]). Treatment was attempted with oral doxycycline and ivermectin combined with a single injection of melarsomine. The mean...

Author(s)
Ikemizu, T.; Shirahama, J.
Publisher
Japanese Society of Clinical Veterinary Medicine, Tottori, Japan
Citation
Journal of Animal Clinical Medicine, 2017, 26, 1, pp 16-23
Abstract

This study aims to evaluate the influence of the phase behavior of microemulsions in the transdermal administration ("spot-on") of ivermectin, an antiparasitic drug widely used in the treatment of endoparasites and ectoparasites in dogs. In this regard, pseudoternary phase diagrams composed of...

Author(s)
Machado, M.; Dantas, I. L.; Galvão, J. G.; Lima, A. D.; Gonsalves, J. K. M. da C.; Almeida, E. D. P.; Araujo, G. R. S. de; Leal, L. B.; Sarmento, V. H. V.; Nunes, R. S.; Lira, A. A. M.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2020, 133, pp 31-38
Abstract

This study examines the therapeutic and year-round prophylactic efficacy of different formulations used in dogs in three Spanish areas where canine thelaziosis is endemic. The study was conducted as a Good Clinical Practice, multicentre, randomised field study in privately owned outdoor dogs...

Author(s)
Marino, V.; Gálvez, R.; Mascuñán, C.; Domínguez, I.; Sarquis, J.; Montoya, A.; Barrera, J. P.; Zenker, C.; Checa, R.; Hernández, M.; Miró, G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
International Journal for Parasitology, 2021, 51, 1, pp 73-81
AbstractFull Text

The present study was carried out to treat a dog that was diagnosed as generalized demodicosis with no response to localized demodicosis treatment that spread of the lesions was aggravated and accelerated subsequently. The material of the study consisted of a 10-month old German shepherd dog....

Author(s)
Köse, O.; Okur, O.
Publisher
Veteriner Hekimler Dernegi, Ankara, Turkey
Citation
Veteriner Hekimler Derneği Dergisi / Journal of the Turkish Veterinary Medical Society, 2020, 91, 2, pp 176-181
AbstractFull Text

Objectives: Demodicosis is a vital skin problem in dogs. The present study has determined the prevalence and associated risk factors of demodicosis in dogs and the response to treatment. Materials and Methods: A total of 100 skin scrapings were collected from dogs having dermatological lesions...

Author(s)
Mizanur Rahman; Bostami, M. B.; Aparna Datta; Sabuj, A. A.; Rana, E. A.; Abdul Mannan; Hossain, M. M. A.; Chowdhury, M. Y. E.
Publisher
Network for the Veterinarians of Bangladesh, Mymensingh, Bangladesh
Citation
Journal of Advanced Veterinary and Animal Research, 2021, 8, 1, pp 116-122
Abstract

Background: A mutation in the canine multidrug resistance MDR1 gene (also referred as ABCB1), encoding for the multidrug resistance (MDR) P-glycoprotein (P-gp) transponder, causes a pathological condition known as 'ivermectin toxicosis'. The causative mutation, known since 2001, has been described...

Author(s)
Marelli, S. P.; Polli, M.; Frattini, S.; Cortellari, M.; Rizzi, R.; Crepaldi, P.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record Open, 2020, 7, e000375,
Abstract

Advocate® (2.5% moxidectin+10% imidacloprid) (Bayer HealthCare, Leverkusen, Germany) is a multiparasiticidal spot-on authorized for treating canine demodicosis in many countries. This blinded, randomized three-phase clinical trial compared its efficacy employing different dosing regimens with that...

Author(s)
Paterson, T. E.; Halliwell, R. E.; Fields, P. J.; Louw, M. L.; Ball, G.; Louw, J.; Pinckney, R.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2014, 205, 3/4, pp 687-696

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