The aim of this prospective, randomized, nonblinded, controlled clinical trial was to compare mean arterial blood pressure (MAP) and heart rate (HR) during an intravenous bolus of three different balanced isotonic crystalloid solutions in euvolemic, anesthetized dogs with hypotension. Thirty...

Repeated replacement of sulphamidase via cerebrospinal fluid injection is an effective treatment for pathological changes in the brain in mice and dogs with the lysosomal storage disorder, mucopolysaccharidosis type IIIA (MPS IIIA). Investigational trials of this approach are underway in children...

The purpose of this study was to evaluate the cardiac acute volume loading effect on left atrial (LA) strain and strain rate (SR) parameters derived from two-dimensional speckle tracking echocardiography (2D-STE) in healthy dogs. Six healthy beagles were anesthetized and subjected to increase...

The use of continuous infusion pumps and perfusers in daily activity has become a common practice that allows for precise and efficient fluid administration. This factor contributes to the emergence of new patterns of continuous drug administration, since this technique is superior to those of...

Sepsis is a clinical syndrome which promotes hemodinamics changes, resulting in hypoperfusion, organ dysfunction and hypotension, those being responsive or not to volemic resuscitation. Non-responsive patients must be treated with vasoactive drugs, such as dopamine and norepinephrine, in order to...