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Veterinary information to support practice, based on evidence and continuing education

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Abstract

Intestinal Mφ play a pivotal role in the maintenance of gut homeostasis, but can also contribute to inflammation such as inflammatory bowel disease (IBD). In contrast to human tissues, little is known about phenotypes of Mφ in the canine gastrointestinal tract. Therefore, an immunohistochemical...

Author(s)
Wagner, A.; Junginger, J.; Lemensieck, F.; Hewicker-Trautwein, M.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2018, 197, pp 49-57
Abstract

Background: Canine inflammatory bowel disease (IBD) is a group of chronic gastrointestinal (GI) disorders of still largely unknown etiology. Canine IBD diagnosis is time-consuming and costly as other diseases with similar signs should be initially excluded. In human IBD microRNA (miR) expression...

Author(s)
Konstantinidis, A. O.; Pardali, D.; Adamama-Moraitou, K. K.; Gazouli, M.; Dovas, C. I.; Legaki, E.; Brellou, G. D.; Savvas, I.; Jergens, A. E.; Rallis, T. S.; Allenspach, K.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2020, 16, 69, pp (22 February 2020)
Abstract

In human medicine, fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection. It has also been tested as a treatment for multiple gastrointestinal diseases, including inflammatory bowel disease (IBD). However, only a few studies have focused...

Author(s)
Niina, A.; Kibe, R.; Suzuki, R.; Yuchi, Y.; Teshima, T.; Matsumoto, H.; Kataoka, Y.; Koyama, H.
Publisher
BMFH Press, Tokyo, Japan
Citation
BMFH - Bioscience of Microbiota, Food and Health, 2021, 40, 2, pp 98-104
Abstract

Background: The use of serological markers to diagnose inflammatory bowel disease (IBD) in humans is well-established. Because of the frequency of IBD in dogs and resources required for its diagnosis with current methods, new approaches are desired. Objective: The goal is to evaluate novel...

Author(s)
Estruch, J. J.; Barken, D.; Bennett, N.; Krawiec, D. K.; Ogilvie, G. K.; Powers, B. E.; Polansky, B. J.; Sueda, M. T.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 3, pp 1177-1186
Abstract

Inflammatory bowel disease (IBD) is a multifactorial chronic inflammatory disorder leading to structural changes in the intestinal wall. In humans, the neutrophil-to-lymphocyte ratio (NLR) has been proposed as a promising marker of IBD. This study evaluated the possible clinical and prognostic...

Author(s)
Benvenuti, E.; Pierini, A.; Gori, E.; Lucarelli, C.; Lubas, G.; Marchetti, V.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2020, 7, 3,
Abstract

Canine inflammatory bowel disease (IBD) is a chronic, immunologically mediated intestinal disorder, resulting from the complex interaction of genetic, environmental and immune factors. Hydrolyzed diets are used in dogs with food-responsive diarrhea (FRD) to reduce adverse responses to...

Author(s)
Ambrosini, Y. M.; Neuber, S.; Borcherding, D.; Seo YeonJung; Segarra, S.; Glanemann, B.; Garden, O. A.; Müller, U.; Adam, M. G.; Dang, V.; Borts, D.; Atherly, T.; Willette, A. A.; Jergens, A.; Mochel, J. P.; Allenspach, K.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2020, 6, July,
Abstract

Background: Inflammatory bowel disease (IBD) commonly occurs in dogs, but there is lack of information about potential biomarkers of clinical and histopathologic severity. Objective: To examine the role of serum C-reactive protein (CRP) and high-mobility group box 1 (HMGB1) concentrations in dogs...

Author(s)
Lee JongHwan; Kim HongSuk; Lee Dohee; Yun Taesik; Koo Yoonhoi; Chae Yeon; Kang JiHoun; Kang ByeongTeck; Yang MhanPyo; Kim Hakhyun
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2021, 35, 5, pp 2205-2214
Abstract

Several extra-intestinal manifestations, including immune-mediated cytopenias, are reported in human inflammatory bowel disease (IBD), whereas they are poorly documented in dogs. Hypothesizing that immune-mediated subclinical anemia can occur in canine IBD, the study aim was to evaluate the...

Author(s)
Gori, E.; Pierini, A.; Nesci, M.; Benvenuti, E.; Tasca, S.; Lubas, G.; Marchetti, V.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2021, 11, 9,
Abstract

Idiopathic inflammatory bowel disease (IBD) in dogs can be challenging to diagnose and fecal markers of disease that correlate with its severity could potentially be clinically useful. Surrogate inflammatory markers, such as the concentration of fecal S100A12, are used to detect active IBD in...

Author(s)
Heilmann, R. M.; Grellet, A.; Allenspach, K.; Lecoindre, P.; Day, M. J.; Priestnall, S. L.; Toresson, L.; Procoli, F.; Grützner, N.; Suchodolski, J. S.; Steiner, J. M.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2014, 158, 3/4, pp 156-166
Abstract

Although antimicrobial peptides (AMPs) play an integral role in the regulation of intestinal microbiota and homeostasis, their expression in canine gastrointestinal diseases, including idiopathic inflammatory bowel disease (IBD) and intestinal lymphoma, remains unknown. The objective of this study...

Author(s)
Nakazawa, M.; Maeda, S.; Omori, M.; Kaji, K.; Yokoyama, N.; Nakagawa, T.; Chambers, J. K.; Uchida, K.; Ohno, K.; Yonezawa, T.; Matsuki, N.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2019, 249, pp 47-52

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