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Abstract

Objectives: The aim of this study was to identify distinguishing characteristics between dogs diagnosed with amegakaryocytic thrombocytopenia and those diagnosed with presumed primary peripheral immune-mediated thrombocytopenia. Presenting clinical and clinicopathologic data and outcomes were...

Author(s)
Cooper, S. A.; Huang, A. A.; Raskin, R. E.; Weng, H. Y.; Scott-Moncrieff, J. C.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2016, 57, 3, pp 142-147
Abstract

Objectives: To investigate whether dogs living in urban areas are more likely to develop immune-mediated disease than those in rural areas. Materials and Methods: A case-control study comparing the prevalence of urban home location between dogs with immune-mediated disease and matched controls. ...

Author(s)
Jeffery, U.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2017, 58, 11, pp 639-644
Abstract

Immune-mediated diseases are common and life-threatening disorders in dogs. Many canine immune-mediated diseases have strong breed predispositions and are believed to be inherited. However, the genetic mutations that cause these diseases are mostly unknown. As many immune-mediated diseases in...

Author(s)
Friedenberg, S. G.; Buhrman, G.; Chdid, L.; Olby, N. J.; Olivry, T.; Guillaumin, J.; O'Toole, T.; Goggs, R.; Kennedy, L. J.; Rose, R. B.; Meurs, K. M.
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Immunogenetics, 2016, 68, 3, pp 205-217
Abstract

Therapeutic plasma exchange (TPE) is an emerging treatment for dogs with immune-mediated diseases, but reports for treatment of immune-mediated thrombocytopenia (IMT) are lacking. These case reports illustrate the application of centrifugal TPE in 4 dogs with IMT. All dogs presented with severe...

Author(s)
Kopecny, L.; Palm, C. A.; Naylor, S.; Kirby, J.; Cowgill, L. D.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 4, pp 1576-1581
Abstract

Background: Therapeutic plasma exchange (TPE) has been used increasingly to treat immunological diseases in dogs, although data concerning its efficacy are lacking. Hypothesis/Objectives: To describe the clinic and the outcome of dogs with immune-mediated hematological disorders (IMHD) treated with ...

Author(s)
Francey, T.; Etter, M.; Schweighauser, A.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2021, 35, 2, pp 925-935
Abstract

Background: In humans, the presence of antiphospholipid antibodies (aPL) is frequently found in immune thrombocytopenia. The present study investigated whether aPL and any aPL subtypes are associated with canine thrombocytopenia, in particular, immune-mediated thrombocytopenia (immune ...

Author(s)
Chen YuChen; Chi LangMing; Chow KuanChih; Chiou ShiowHer; Fan YiHsin; Ho ShuPeng; Hsu YuChen; Hwang YuChyi; Wu MengXing; Lee WeiMing; Lin ShiunLong; Tsang ChauLoong; Mao FrankChiahung
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2016, 12, 106, pp (13 June 2016)
Abstract

Background: Immune-mediated thrombocytopenia (IMT) is the most common cause of severe thrombocytopenia (<30000 platelets/µl) in dogs and at this level or below there is an increased risk of spontaneous body surface bleeding (cutaneous and mucosal). Despite this, some patients with IMT are asymptomatic with no evidence of...

Author(s)
Whitley, N.
Publisher
BMJ Publishing Group, London, UK
Citation
In Practice, 2020, 42, 1, pp 20-25
Abstract

Objectives: The objective of this study was to compare hospitalisation duration, survival times, adverse events and cost of therapy in dogs with presumptive primary immune-mediated thrombocytopenia undergoing therapy with mycophenolate mofetil and corticosteroids versus cyclosporine and...

Author(s)
Cummings, F. O.; Rizzo, S. A.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2017, 58, 2, pp 96-102
AbstractFull Text

Background: Splenic infarction (SI) is a rare clinical entity seldom encountered in veterinary medicine. Its most frequent causes include thromboembolic status, splenomegaly, and cardiac disease. Although thrombotic elements from the circulation provide the most common context for thromboembolic...

Author(s)
Kim, S. M.; Ki, G. N.; Jeong, S. W.; Kim, J. H.
Publisher
Shiraz University, Shiraz, Iran
Citation
Iranian Journal of Veterinary Research, 2020, 21, 1, pp 65-69
Abstract

Objectives: To establish whether heightened platelet activation is a common feature of canine immune-mediated haemolytic anaemia, and to evaluate the hypothesis that platelet activation plays a role in the pathogenesis of thromboembolism. Methods: Using whole-blood flow-cytometric analysis, the...

Author(s)
Ridyard, A. E.; Shaw, D. J.; Milne, E. M.
Publisher
Blackwell Publishing Ltd, Oxford, UK
Citation
Journal of Small Animal Practice, 2010, 51, 6, pp 296-304

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