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Abstract

Objectives: The aim of this study was to identify distinguishing characteristics between dogs diagnosed with amegakaryocytic thrombocytopenia and those diagnosed with presumed primary peripheral immune-mediated thrombocytopenia. Presenting clinical and clinicopathologic data and outcomes were...

Author(s)
Cooper, S. A.; Huang, A. A.; Raskin, R. E.; Weng, H. Y.; Scott-Moncrieff, J. C.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2016, 57, 3, pp 142-147
Abstract

Objectives: To investigate whether dogs living in urban areas are more likely to develop immune-mediated disease than those in rural areas. Materials and Methods: A case-control study comparing the prevalence of urban home location between dogs with immune-mediated disease and matched controls. ...

Author(s)
Jeffery, U.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2017, 58, 11, pp 639-644
Abstract

Immune-mediated diseases are common and life-threatening disorders in dogs. Many canine immune-mediated diseases have strong breed predispositions and are believed to be inherited. However, the genetic mutations that cause these diseases are mostly unknown. As many immune-mediated diseases in...

Author(s)
Friedenberg, S. G.; Buhrman, G.; Chdid, L.; Olby, N. J.; Olivry, T.; Guillaumin, J.; O'Toole, T.; Goggs, R.; Kennedy, L. J.; Rose, R. B.; Meurs, K. M.
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Immunogenetics, 2016, 68, 3, pp 205-217
Abstract

Background: In humans, the presence of antiphospholipid antibodies (aPL) is frequently found in immune thrombocytopenia. The present study investigated whether aPL and any aPL subtypes are associated with canine thrombocytopenia, in particular, immune-mediated thrombocytopenia (immune ...

Author(s)
Chen YuChen; Chi LangMing; Chow KuanChih; Chiou ShiowHer; Fan YiHsin; Ho ShuPeng; Hsu YuChen; Hwang YuChyi; Wu MengXing; Lee WeiMing; Lin ShiunLong; Tsang ChauLoong; Mao FrankChiahung
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2016, 12, 106, pp (13 June 2016)
Abstract

Objectives: The objective of this study was to compare hospitalisation duration, survival times, adverse events and cost of therapy in dogs with presumptive primary immune-mediated thrombocytopenia undergoing therapy with mycophenolate mofetil and corticosteroids versus cyclosporine and...

Author(s)
Cummings, F. O.; Rizzo, S. A.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2017, 58, 2, pp 96-102
Abstract

Objectives: To establish whether heightened platelet activation is a common feature of canine immune-mediated haemolytic anaemia, and to evaluate the hypothesis that platelet activation plays a role in the pathogenesis of thromboembolism. Methods: Using whole-blood flow-cytometric analysis, the...

Author(s)
Ridyard, A. E.; Shaw, D. J.; Milne, E. M.
Publisher
Blackwell Publishing Ltd, Oxford, UK
Citation
Journal of Small Animal Practice, 2010, 51, 6, pp 296-304
Abstract

Objectives: To report the outcomes associated with the use of rabbit anti-dog thymocyte serum in dogs with haematological immune-mediated diseases. Methods: Medical records from 2000 to 2016 of patients diagnosed with immune-mediated haemolytic anaemia, immune-mediated thrombocytopenia,...

Author(s)
Cuq, B.; Blois, S. L.; Mathews, K. A.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2017, 58, 6, pp 348-354
Abstract

Background: Relapses of immune-mediated hemolytic anemia (IMHA), thrombocytopenia (ITP), or polyarthropathy (IMPA) occur despite normal hematologic and cytologic parameters. Thymidine kinase 1 (TK1), canine C-reactive protein (c-CRP), haptoglobin (HPT), and 25-Hydroxyvitamin-D (25(OH)D) might be...

Author(s)
Grobman, M.; Outi, H.; Rindt, H.; Reinero, C.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 5, pp 1430-1440
Abstract

Objectives: To describe, in a cohort of dogs with presumed primary immune-mediated neutropenia, the presenting clinical characteristics, haematology results, bone marrow characteristics, therapies used (drugs and doses), clinical response to treatment, relapse and outcome at six months and one...

Author(s)
Devine, L.; Armstrong, P. J.; Whittemore, J. C.; Sharkey, L.; Bailiff, N.; Huang, A.; Rishniw, M.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2017, 58, 6, pp 307-313
Abstract

Objectives: To determine the incidence of relapse after discharge from the hospital in dogs with a diagnosis of presumed primary immune-mediated thrombocytopenia, risk factors associated with relapse and whether or not indefinite use of immunosuppressive medication influences risk of relapse....

Author(s)
Simpson, K.; Chapman, P.; Klag, A.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2018, 59, 11, pp 674-680

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