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Abstract

Background: Recent reports indicate that the isoxazoline compounds have the potential to provide safe and effective treatment of canine generalized demodicosis, a condition that has been traditionally difficult to cure. Controlled field studies are needed to confirm this potential. A study was...

Author(s)
Petersen, I.; Chiummo, R.; Zschiesche, E.; Karas-Tecza, J.; Rapti, D.; Roepke, R.; Thomas, E.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2020, 13, 304, pp (11 June 2020)
Abstract

Canine heartworm disease (CHD) results from infection with Dirofilaria immitis and while it is of global concern, it is most prevalent in tropical climates where conditions support the parasite and vector life cycles. Melarsomine dihydrochloride is the sole treatment for CHD recommended by the...

Author(s)
Paterson, T.; Fernandez, C.; Burnett, P. J.; Lessey, L.; Hockley, T.; Hagen, R.; Coomansingh, C.; Sharma, B.; Chandrashekar, R.; Schaper, R.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2020, 284,
Abstract

Background: Canine demodicosis is classified as localised or generalised according to the extent of the disease. Chronic generalised demodicosis is a difficult skin disease to treat and unlikely to resolve without therapy. This laboratory study compared the efficacy of two topical spot-on...

Author(s)
Fourie, J. J.; Meyer, L.; Thomas, E.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2019, 12, 59, pp (25 January 2019)
Abstract

Background - Treatment of canine demodicosis can be challenging; new treatments are always being sought. Objective - The efficacy of sarolaner was evaluated in comparison with a moxidectin/imidacloprid topical product against generalized demodicosis in dogs in a randomized, single-masked,...

Author(s)
Becskei, C.; Cuppens, O.; Mahabir, S. P.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2018, 29, 3, pp 203-e72
Abstract

PICO question: In dogs with generalised demodicosis, are isoxazolines as effective as a combined formulation of imidacloprid and moxidectin at reducing mite count and the severity of associated clinical signs? Clinical bottom line: Five single-blinded, randomised, positive control trials, most...

Author(s)
Long, S.
Publisher
RCVS Knowledge, London, UK
Citation
Veterinary Evidence, 2019, 4, 2,
Abstract

Capillaria boehmi affects the upper respiratory tract of domestic and wild canids. The aim of the present study was to investigate the efficacy of a spot-on formulation containing imidacloprid and rnoxidectin in dogs naturally infected by C. boehmi. Twenty dogs infected with C. boehmi were randomly ...

Author(s)
Morganti, G.; Veronesi, F.; Cesare, A. di; Braun, G.; Günther, L.; Rueca, F.; Petry, G.; Schaper, R.; Traversa, D.
Publisher
Point Vétérinaire Italie s.r.l., Milano, Italy
Citation
Summa, Animali da Compagnia, 2018, 35, 10, pp 44-49
Abstract

Canines are proven reservoir hosts of Leishmania infantum, the causative agent of human zoonotic visceral leishmaniasis, and therefore domestic dogs play a central role in transmitting the disease to humans. Studies on the effect of insecticide-impregnated dog collars for controlling canine...

Author(s)
Yimam, Y.; Mohebali, M.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2020, 15, 9,
Abstract

Background: A prospective clinical study evaluated the tolerance and the efficacy of a combination of imidacloprid (10%) and permethrin (50%) (ADVANTIX®: Bayer HC AH, France) applied topically as a spot-on, for the treatment of natural canine fly dermatitis due to Stomxys calcitrans. The study was...

Author(s)
Castilla-Castaño, E.; Moog, F.; Mandin-Cabaret, C.; Pressanti, C.; Cadiergues, M. C.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2019, 12, 132, pp (21 March 2019)
Abstract

Background: Various treatments are available for ear mite infestations in dogs. Objective: The efficacy of sarolaner was evaluated against ear mite infestation caused by Otodectes cynotis in dogs and compared with topical moxidectin/imidacloprid in a single-masked, multi-centre field study....

Author(s)
Becskei, C.; Cuppens, O.; Mahabir, S. P.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2018, 29, 2, pp 100-e39
Abstract

Neonicotinoid insecticides are used for agricultural and non-agricultural purposes worldwide. Pets are directly exposed to neonicotinoids in veterinary products and through environmental contamination. Cytochrome P450 (CYP) is among the most significant xenobiotic metabolizing enzymes that oxidizes ...

Author(s)
Khidkhan, K.; Ikenaka, Y.; Ichise, T.; Nakayama, S. M. M.; Mizukawa, H.; Nomiyama, K.; Iwata, H.; Arizono, K.; Takahashi, K.; Kato, K.; Ishizuka, M.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Comparative Biochemistry and Physiology. C, Toxicology & Pharmacology, 2021, 239,

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