Background: Fibroblast growth factor (FGF)-23 is increased first in the sequence of changes associated with chronic kidney disease (CKD)-mineral and bone disorder. Thus, its measurement may serve as a predictive indicator of incident hyperphosphatemia. Objectives: To investigate whether serum...
Author(s)
Miyakawa, H.; Hsu, H. H.; Ogawa, M.; Akabane, R.; Miyagawa, Y.; Takemura, N.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2021, 35, 5, pp 2296-2305
The increase of urinary fractional excretion of phosphorus (uFEP) may indicate phosphorus retention before the onset of hyperphosphatemia in the early stages of chronic kidney disease (CKD). The hypothesis of this study is whether uFEP may increase during the early stage of CKD as a compensatory...
Author(s)
Martorelli, C. R.; Kogika, M. M.; Chacar, F. C.; Caragelasco, D. S.; Pinto, A. C. B. de C. F.; Lorigados, C. A. B.; Andrade, L. C.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2017, 4, 4, pp 67
Background: Abnormal total calcium (tCa) values do not necessarily imply dysregulated ionized calcium. Objectives: We aimed to evaluate the diagnostic performance of predicted ionized calcium (piCa) regarding true calcium status in dogs with abnormal tCa. Methods: This was a cross-sectional...
Author(s)
Lebastard, M.; Cuq, B.; Sharman, M. J.; Danner, J.; Boedec, K. le
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2021, 50, 4, pp 515-524
Background: Ionized calcium (iCa) is the biologically active fraction of total calcium (tCa) with clinical relevance to evaluate calcium homeostasis, but not all primary veterinarians have access to serum iCa. Formulas that adjust tCa to correct for variability in serum protein concentrations were...
Author(s)
Witte, F. de; Klag, A.; Chapman, P.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2021, 35, 5, pp 2249-2255
Objectives: To examine the relationship between fibroblast growth factor-23 levels, chronic kidney disease severity and mineral metabolic disorders associated to chronic kidney disease in dogs. Materials and Methods: Fifteen control and 75 chronic kidney disease dogs were retrospectively included....
Author(s)
Miyakawa, H.; Nagatani, Y.; Ogawa, M.; Nagakawa, M.; Sakatani, A.; Akabane, R.; Miyagawa, Y.; Takemura, N.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2020, 61, 12, pp 744-751
The occurrence of acute kidney injury in canine babesiosis is not well documented. Furthermore, interpretation of urine specific gravity (USG) to assess renal concentrating ability is hampered by the frequent presence of hemoglobinuria in this disease. This cross-sectional study aimed to test the...
Author(s)
Defauw, P.; Daminet, S.; Leisewitz, A. L.; Goddard, A.; Paepe, D.; Duchateau, L.; Schoeman, J. P.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2018, 260, pp 22-29
Hyperphosphatemia is associated with renal secondary hyperparathyroidism (SRHP) and chronic kidney disease (CKD) progression. Phosphorus retention stimulates the synthesis of fibroblast growth factor 23 (FGF-23), which promotes phosphaturia in order to avoid the onset of hyperphosphatemia....
Author(s)
Martorelli, C. R.
Publisher
Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, Brazil
Citation
Avaliação sequencial do metabolismo de cálcio e fósforo com ênfase na determinação do fator de crescimento de fibroblastos 23 (FGF-23) e da excreção fracionada de fósforo urinária (uFEP) de cães com doença renal crônica submetidos a terapia com células-tronco mesenquimal, 2016, pp 155 pp.
Background: Hypercortisolism affects calcium and phosphate metabolism in dogs; however, the exact mechanisms are not completely understood. Objectives: To evaluate circulating concentrations of whole parathormone (wPTH), 25-hydroxyvitamin D (25-(OH)D), calcitriol, and fibroblast growth factor-23...
Author(s)
Corsini, A.; Dondi, F.; Serio, D. G.; Zamagni, S.; Golinelli, S.; Fernandez, M.; Fracassi, F.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2021, 35, 3, pp 1265-1273
Renal maldevelopment (RM) has been proposed to replace the old and sometimes misused term "renal dysplasia" in dogs. Although renal dysplasia has been described in Boxers, hereditary transmission has only been hypothesized. This study reports clinical and renal histological findings in Boxer dogs...
Author(s)
Cavalera, M. A.; Gernone, F.; Uva, A.; D'Ippolito, P.; Roura, X.; Zatelli, A.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2021, 11, 3,
Background: Total serum calcium (tCa) concentrations are poorly predictive of ionized calcium (iCa) status in dogs. Hypothesis: There is an optimal threshold of tCa concentration that is highly predictive of ionized hypercalcemia and this threshold is higher in hyperphosphatemic dogs as compared to ...
Author(s)
Groth, E. M.; Chew, D. J.; Lulich, J. P.; Tommet, M.; Rendahl, A. K.; Husbands, B. D.; Furrow, E.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 1, pp 74-82