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AbstractFull Text

BACKGROUND: Canine low-dose sepsis model provides a reliable setting to study innovative drugs. Lipopolysaccharides (LPS), a major constituent of bacterial outer membrane, have been demonstrated to play a critical role in the initiation of pathogenesis. Lipopolysaccharide-induced sepsis has been...

Author(s)
Soltanian, A.; Mosallanejad, B.; Jalali, M. R.; Varzi, H. N.; Najafabadi, M. G.
Publisher
Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Citation
Iranian Journal of Veterinary Medicine, 2019, 13, 4, pp 377-387
Abstract

OBJECTIVE: To determine effects of hydrocortisone administration on serum leptin and adiponectin concentrations, abdominal fat distribution, and mRNA expression of leptin and adiponectin in abdominal adipose tissue of dogs. ANIMALS: 12 healthy dogs. PROCEDURES: Dogs received hydrocortisone (8.5...

Author(s)
Choo HyeRyung; Kim HakHyun; Kang JiHoun; Sung ChanJoo; Ahn ChangHwan; Kang ByeongTeck; Chang DongWoo; Jeung EuiBae; Yang MhanPyo
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2019, 80, 8, pp 771-778
Abstract

Background: Oclacitinib is an effective systemic therapy for dogs with atopic dermatitis (AD). Few studies have evaluated concurrent topical treatment with oclacitinib in dogs. Objectives: To evaluate the efficacy and safety of combination therapy of oclacitinib and 0.0584% hydrocortisone aceponate ...

Author(s)
Takahashi, J.; Kanda, S.; Imanishi, I.; Hisano, T.; Fukamachi, T.; Taguchi, N.; Momiyama, S.; Nishiyama, S.; Motegi, T.; Iyori, K.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2020, 32, 2, pp 119-e25
Abstract

Among domestic animal species, the reproductive biology of the dog belongs to the most peculiar. This includes the conceptus-maternal communication and endocrine mechanisms involved in maintenance of pregnancy. Dogs fully depend on luteal progesterone (P4) throughout pregnancy, with similar steroid ...

Author(s)
Kowalewski, M. P.; Pereira, M. T.; Kazemian, A.
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2020, 150, pp 329-338
AbstractFull Text

The present study aimed to examine the effectiveness of silymarin compared to hydrocortisone on clinical and hematological alterations and organ injury (liver and heart) in a low-dose canine lipopolysaccharide (LPS)-induced sepsis model. Fifteen clinically healthy dogs were randomly categorized...

Author(s)
Soltanian, A.; Mosallanejad, B.; Jalali, M. R.; Varzi, H. N.; Ghorbanpoor, M.
Publisher
Urmia University, Faculty of Veterinary Medicine, Urmia, Iran
Citation
Veterinary Research Forum, 2020, 11, 3, pp 235-241
Abstract

Therapy dogs provide health benefits for individuals who suffer from illnesses, such as dementia, depression, loneliness, and aggression. Therapy dogs' impact on human health has been thoroughly studied; however, studies on dog welfare have been limited. Additionally, as dogs have evolved with...

Author(s)
Clark, S. D.; Smidt, J. M.; Bauer, B. A.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2020, 6, November,
Abstract

Canine parvovirus (CPV-2), a member of Parvoviridae, mainly affects puppies and it is a major cause of vomiting and diarrhea in canine; sometimes, it has fatal outcomes. This study aims to scrutinize the alterations in hematology as well as oxidative stress biomarkers in association with CPV-2...

Author(s)
Elsayed, N. M.; Kubesy, A. A.; Salem, N. Y.
Publisher
Springer Science + Business Media, London, UK
Citation
Comparative Clinical Pathology, 2020, 29, 2, pp 355-359
Abstract

Critical illness due to sepsis is a major global health concern associated with a high burden of mortality and cost. Glucocorticoid dysregulation in human sepsis is associated with poorer outcomes. This study examines glucocorticoid metabolism in septic canine patients to delineate elements of...

Author(s)
Boag, A. M.; Brown, A.; Koenigshof, A.; Homer, N.; Sooy, K.; Jamieson, P. M.
Publisher
Elsevier Inc, New York, USA
Citation
Domestic Animal Endocrinology, 2020, 72,
Abstract

The enzyme 11-beta-hydroxysteroid dehydrogenase isoenzyme 2 (11BHSD2) is responsible for converting the active glucocorticoid cortisol to inactive cortisone and in the renal medulla protects the mineralocorticoid receptor (MR) from activation by cortisol. Derangements in 11BHSD2 activity can result ...

Author(s)
Bode, E. F.; Markby, G. R.; Boag, A. M.; Martinez-Pereira, Y.; Corcoran, B. M.; Farquharson, C.; Sooy, K.; Homer, N. Z. M.; Jamieson, P. M.; Culshaw, G. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2020, 258,
AbstractFull Text

Gastritis is one of most common clinical complication in canines. The disease has multifactorial etiology and on most occasions, the exact etiology remains undetermined. The present study is an attempt to study the alteration in hematological and biochemical parameters in gastritis to delineate the ...

Author(s)
Patel, P. K.; Dixit, S. K.; Akhilesh Kumar; Saxena, A. C.; Verma, N. K.; Bhatt, S.
Publisher
College of Veterinary Sciences, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, India
Citation
Haryana Veterinarian, 2020, 59, Special Issue, pp 87-89

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