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Abstract

Canine herpesvirus-1 (CHV-1) is recognized to be enzootic in the dog population with a widespread distribution. This pathogen leads to a lethal generalized illness in newborn puppies and is associated with reproductive disorders. CHV-1 should be considered as an important pathogen of neonatal death ...

Author(s)
Rezaei, M.; Jajarmi, M.; Alizadeh, R.; Khalili, M.; Babaei, H.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Comparative Immunology, Microbiology & Infectious Diseases, 2020, 71,
Abstract

Aims: The aim of this study was to identify viruses associated with canine infectious respiratory disease syndrome (CIRDS) among a population of New Zealand dogs. Methods: Convenience samples of oropharyngeal swabs were collected from 116 dogs, including 56 CIRDS-affected and 60 healthy dogs from...

Author(s)
More, G. D.; Cave, N. J.; Biggs, P. J.; Acke, E.; Dunowska, M.
Publisher
Taylor & Francis, Melbourne, Australia
Citation
New Zealand Veterinary Journal, 2021, 69, 4, pp 224-233
Abstract

The canine infectious respiratory disease complex (CIRDC) is an endemic worldwide syndrome involving multiple viral and bacterial pathogens. Traditionally, Bordetella bronchiseptica (Bb), canine adenovirus type 2 (CAV-2), canine distemper virus (CDV), canine herpesvirus (CHV) and canine...

Author(s)
Day, M. J.; Carey, S.; Clercx, C.; Kohn, B.; Marsilio, F.; Thiry, E.; Freyburger, L.; Schulz, B.; Walker, D. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Comparative Pathology, 2020, 176, pp 86-108
Abstract

Latent canine herpesvirus-1 (CHV-1) infections are common in domestic dogs and reactivation of latent virus may be associated with recurrent ocular disease. The objectives of the present study were to evaluate the ability of a subunit CHV-1 vaccine to stimulate peripheral CHV-1 specific immunity...

Author(s)
Ledbetter, E. C.; Kim Kay; Dubovi, E. J.; Mohammed, H. O.; Felippe, M. J. B.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2016, 197, pp 102-110
Abstract

Latent canine herpesvirus-1 (CHV-1) infection is common in domestic dogs, but triggers for viral reactivation and recrudescent CHV-1 disease are poorly understood. Cyclophosphamide is a potent immunosuppressive and myelosuppressive agent used for the therapy of a variety of neoplastic and...

Author(s)
Mundy, P.; Silva, E. C. da; Ledbetter, E. C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Microbiology, 2012, 159, 1/2, pp 230-235
Abstract

Canine herpesvirus-1 (CHV-1) can cause abortion and foetal and neonatal deaths in the bitch. The reactivation of latent infections with asymptomatic virus shedding represents a mechanism, whereby the virus can persist in a dog population. The aim of this study was to investigate the seroprevalence...

Author(s)
Rota, A.; Dogliero, A.; Biosa, T.; Messina, M.; Pregel, P.; Masoero, L.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2020, 10, 7,
Abstract

Latent canine herpesvirus-1 (CHV-1) infections are common in domestic dogs, but stimuli causing viral reactivation and recrudescent disease are poorly understood. Immunosuppressive pharmaceuticals are currently the only experimentally established triggers for recurrent ocular CHV-1 infection in ...

Author(s)
Nicklin, A. M.; McEntee, M. C.; Ledbetter, E. C.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2014, 174, 3/4, pp 433-437
Abstract

OBJECTIVE: To determine the in vitro half maximal effective concentration (EC50) of ganciclovir for canine herpesvirus-1 (CHV-1) and to evaluate the efficacy of ganciclovir ophthalmic gel in dogs with experimentally induced ocular CHV-1 infection. ANIMALS: 10 specific pathogen-free adult Beagles....

Author(s)
Ledbetter, E. C.; Nicklin, A. M.; Spertus, C. B.; Pennington, M. R.; Walle, G. R. van de; Mohammed, H. O.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2018, 79, 7, pp 762-769
Abstract

Wild raccoon dogs (Nyctereutes procyonoides koreensis) may play a role transmitting several pathogens to humans and pet animals. Information concerning the incidence of rabies, canine distemper virus (CDV), canine parvovirus (CPV), canine adenovirus type 2 (CAdV-2), canine parainfluenza virus type...

Author(s)
Yang DongKun; Lee SeougHeon; Kim HaHyun; Kim JongTaek; Ahn SangIn; Cho InSoo
Publisher
Korean Society of Veterinary Science, Daejon, Korea Republic
Citation
Korean Journal of Veterinary Research, 2017, 57, 4, pp 209-214
Abstract

Objective-To determine the frequency of spontaneous canine herpesvirus-1 (CHV-1) reactivation and ocular viral shedding in latently infected dogs and the effect of topical ocular administration of cyclosporine. Animals-8 mature Beagles with experimentally induced latent CHV-1 infection....

Author(s)
Ledbetter, E. C.; Silva, E. C. da; Kim, S. G.; Dubovi, E. J.; Schwark, W. S.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2012, 73, 7, pp 1079-1084

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