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Abstract

Objective: To determine the differences in serum canine pancreatic lipase immunoreactivity between dogs with intervertebral disc herniation and healthy control dogs. Materials and Methods: Eighty-four client-owned dogs with intervertebral disc herniation, diagnosed by neurologic examination and...

Author(s)
Schueler, R. O.; White, G.; Schueler, R. L.; Steiner, J. M.; Wassef, A.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2018, 59, 5, pp 305-310
Abstract

Objectives: To document the prevalence of cardiac abnormalities in dogs with steroid-responsive meningitis arteritis and to assess resolution of these abnormalities following corticosteroid therapy. Materials and methods: Steroid-responsive meningitis arteritis was diagnosed based on signalment,...

Author(s)
Spence, S.; French, A.; Penderis, J.; Macfarlane, L.; Gutierrez-Quintana, R.; Dickson, L.; Holmes, K.; McLauchlan, G.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2019, 60, 4, pp 204-211
Abstract

Objectives: To describe the presentation, influence of previous treatment and diagnosis in juvenile dogs presenting with pyrexia to a UK referral centre. Materials and methods: Clinical records of dogs aged 1 to 18 months presenting with a problem list including pyrexia (≥39.2°C) that was...

Author(s)
Black, V. L.; Whitworth, F. J. S.; Adamantos, S.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2019, 60, 2, pp 116-120
Abstract

Background: Progressive myelomalacia (PMM) is a usually fatal complication of acute intervertebral disc extrusion (IVDE) in dogs but its risk factors are poorly understood. The objective of this retrospective case-control study was to identify risk factors for PMM by comparing dogs with complete...

Author(s)
Castel, A.; Olby, N. J.; Ru HongYu; Mariani, C. L.; Muñana, K. R.; Early, P. J.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2019, 15, 433, pp (03 December 2019)
Abstract

Corticosteroids are one of the most extensively used class of therapeutic agents in dogs. In human patients, response to corticosteroid therapy has been correlated with the presence of certain polymorphisms of the glucocorticoid receptor gene (NR3C1). Depending on the polymorphism present, patients ...

Author(s)
Costa, A.; Sellon, R. K.; Court, M.; Burke, N. S.; Mealey, K. L.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2016, 39, 1, pp 16-21
Abstract

Background: Activation of the hypothalamic-pituitary-adrenal-(HPA-) axis and the sympathetic nervous system are essentially involved in the acute phase response in critically ill patients. Inadequate elevation of endogenous cortisol level and/or impaired glucocorticoid sensitivity of target cells...

Author(s)
Csőndes, J.; Kiss, G.; Máthe, Á.; Vajdovich, P.
Publisher
NAKVI, Budapest, Hungary
Citation
Magyar Állatorvosok Lapja, 2016, 138, 11, pp 681-693
Abstract

Background: Current advances in immunotherapy are an exciting area of study in canine osteosarcoma (OSA). The objective of this study was to determine the immune response in dogs with osteosarcoma by measuring stimulated leukocyte production of tumor necrosis factor (TNF), interleukin (IL)-6, IL-10 ...

Author(s)
Axiak-Bechtel, S. M.; Mathew, L. M.; Amorim, J. R.; DeClue, A. E.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Medicine and Science, 2019, 5, 4, pp 485-493
Abstract

Objective: To reveal the relationship between canine corticosteroid-induced alkaline phosphatase isoenzyme activity and hepatobiliary diseases. Materials and Methods: Retrospective analysis of the relationship between serum corticosteroid-induced alkaline phosphatase activity and diagnosis, serum...

Author(s)
Kojima, K.; Ohno, K.; Kanemoto, H.; Goto-Koshino, Y.; Fukushima, K.; Tsujimoto, H.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2017, 58, 5, pp 257-262
Abstract

Literature describing medical treatment of canine prostatic carcinoma (PC) is sparse. The aims of this study were to assess outcomes, including time to progression (TTP) and median survival time (MST), of canine PC treated with non-steroidal anti-inflammatory drugs (NSAIDs) and/or chemotherapy, and ...

Author(s)
Ravicini, S.; Baines, S. J.; Taylor, A.; Amores-Fuster, I.; Mason, S. L.; Treggiari, E.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2018, 16, 4, pp 450-458
Abstract

Background - Mapracorat is a nonsteroidal Selective Glucocorticoid Receptor Agonist (SEGRA) that is presumed to have a better therapeutic index compared to classical glucocorticoids. Objectives - To compare the efficacy and safety of mapracorat with classical glucocorticoids used for the treatment...

Author(s)
Bäumer, W.; Rossbach, K.; Schmidt, B. H.
Publisher
John Wiley & Sons, Chichester, UK
Citation
Advances in veterinary dermatology, Volume 8, 2017, pp 47-54

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