Cookies on VetMed Resource

Like most websites we use cookies. This is to ensure that we give you the best experience possible.

 

Continuing to use www.cabi.org  means you agree to our use of cookies. If you would like to, you can learn more about the cookies we use.

VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

Sign up to receive our Veterinary & Animal Sciences e-newsletter, book alerts and offers direct to your inbox.

Results per page:

Search results

Abstract

5-Fluorouracil (5-FU) is used in combination chemotherapy protocols for human head and neck cancer and other epithelial neoplasms. However, a paucity of literature describing use of this drug in veterinary oncology exists, likely due to previous reports of fatal neurotoxicity in both dogs and cats, ...

Author(s)
Menard, K.; Flesner, B. K.; Glahn, A.; Boudreaux, B.; Bryan, J. N.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2018, 16, 4, pp 590-595
AbstractFull Text

Canine mammary tumors are the most common neoplasms in intact female dogs. The surgery cannot always solve the problem, chemotherapy are recommend to these patients. However, chemotherapy could always fail because of multidrug resistance (MDR). Through stepwise increasing 5-Fluorouracil (5-FU)...

Author(s)
Zhou, B.; Zhang, D.; Pei, S. M.; Zhang, H.; Du, H. C.; Jin, Y. P.; Lin, D. G.
Publisher
Polish Academy of Sciences, Committee of Veterinary Sciences, Olsztyn-Kortowo II, Poland
Citation
Polish Journal of Veterinary Sciences, 2017, 20, 1, pp 103-110
Abstract

Objective: To describe the first documented case of oxidant-induced anemia in a dog associated with propofol and IV lipid emulsion (IVLE) treatment for 5-fluorouracil (5-FU) toxicosis. Case Summary: A 2-year-old male intact mixed breed dog was presented for evaluation after ingestion of 5% 5-FU...

Author(s)
Romans, C. W.; Day, T. K.; Smith, J. J.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Emergency and Critical Care, 2020, 30, 4, pp 481-486
Abstract

5-Fluorouracil is an antineoplastic drug with a narrow therapeutic window. Pets are commonly exposed to the cream used for pre-malignant and malignant skin lesions in humans. 5-Fluorouracil poisoning is characterised by severe gastrointestinal (vomiting; diarrhoea; and gastrointestinal ulceration...

Author(s)
Bates, N.
Publisher
MA Healthcare Limited, London, UK
Citation
Companion Animal, 2019, 24, 6, pp 288-292
Abstract

The ability of chemotherapeutic agents to affect the growth of common bacterial pathogens and the relationship between the effects of chemotherapeutics and antimicrobials is largely unknown. The purpose of this study was to describe the susceptibility of canine bacterial isolates to...

Author(s)
Campbell, O.; Gagnon, J.; Rubin, J. E.
Publisher
Wiley, Oxford, UK
Citation
Letters in Applied Microbiology, 2019, 69, 5, pp 353-357
Abstract

The purpose of this report is to discuss the use of topical 1% 5-fluorouracil as a sole therapy for canine corneal squamous cell carcinoma (SCC). A 12-year-old castrated male pug was evaluated for a well-demarcated, central, 3 mm in diameter, pale pink, raised, right corneal mass. An incisional...

Author(s)
Dorbandt, D. M.; Driskell, E. A.; Hamor, R. E.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Ophthalmology, 2016, 19, 3, pp 256-261
Abstract

Blood circulates as a liquid containing cells and numerous chemicals; it functions to transport nutrients, chemicals, oxygen and waste products to and from cells, and is involved in defence and wound repair to tissues. Numerous toxic substances can disrupt the normal function of the blood through...

Author(s)
Bates, N.
Publisher
MA Healthcare Limited, London, UK
Citation
Companion Animal, 2020, 25, 6, pp 184-190
Abstract

Blood circulates as a liquid containing cells and numerous chemicals; it functions to transport nutrients, chemicals, oxygen and waste products to and from cells, and is involved in defence and wound repair to tissues. Numerous toxic substances can disrupt the normal function of the blood through...

Author(s)
Bates, N.
Publisher
MA Healthcare Limited, London, UK
Citation
The Veterinary Nurse, 2019, 10, 4, pp 196-203
AbstractFull Text

The present study was conducted for exploring the activity of anti-angiogenic and chemotherapeutic treatment with or without cox-2 inhibitor and immunomodulator drug in the management of spontaneous canine mammary neoplasms. Antiangiogenic drug (Tamoxifen) (n=10), chemotherapy (5-FU) (n=10),...

Author(s)
Dileepkumar, K. M.; Maiti, S. K.; Naveen Kumar; Shams-uz-Zama, M. M.
Publisher
Faculty of Veterinary Science, University of Agriculture, Faisalabad, Pakistan
Citation
Pakistan Veterinary Journal, 2015, 35, 3, pp 365-370
Abstract

Purpose: To describe the use of a pulse-dose topical 5-fluorouracil (5-FU) treatment regimen in a Pug dog with corneal squamous cell carcinoma (SCC). Methods: A 1-year-old, spayed female Pug was evaluated for a corneal perforation of the right eye, which was surgically stabilized with a...

Author(s)
Overton, T. L.; Allbaugh, R. A.; Whitley, D.; Ben-Shlomo, G.; Griggs, A.; Tofflemire, K. L.; Whitley, E. M.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Ophthalmology, 2015, 18, 4, pp 350-354

Refine Results

Sort Order
Author
Geographical Location
Item Type
Language
Organisms
Subject Topics