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Abstract

OBJECTIVE: To determine the pharmacokinetics of florfenicol, terbinafine, and betamethasone acetate after topical application to canine auricular skin and the influence of synthetic canine cerumen on pharmacokinetics. SAMPLE: Auricular skin from 6 euthanized shelter dogs (3 females and 3 neutered...

Author(s)
Ehling, S.; Baynes, R. E.; Bäumer, W.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2018, 79, 3, pp 333-341
Abstract

This proceedings contain 25 topics on whole genome sequencing to explore genetic risk factors in canine myxomatous mitral valve disease, evaluation of radiographic predictors of left heart enlargement in dogs, short-term outcome of a prospective study of diet-associated dilated cardiomyopathy (DCM) ...

Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 6, pp 2817-2989
AbstractFull Text

The aims of this study were to evaluate the in vitro antibacterial activity of a florfenicol and tylosin mixture and to determine the pharmacokinetic parameters of each drug following administration of the 2:1 florfenicol and tylosin mixture in beagle dogs. The antibacterial activity of the two...

Author(s)
Mechesso, A. F.; Lee, S. J.; Park, N. H.; Park, S. C.
Publisher
Czech Academy of Agricultural Sciences, Prague, Czech Republic
Citation
Veterinární Medicína, 2018, 63, 7, pp 329-334
AbstractFull Text

The aim of this study was to evaluate the effect of florfenicol treatment at doses of 10 and 20 mg/kg administered IM, in the treatment of canine pyoderma due to Staphylococcus intermedius, using pharmacokinetic/pharmacodynamic modelling (PK/PD). A Monte Carlo simulation of the pharmacokinetic and...

Author(s)
Tameirão, E. R.; Soares, B. C. F.; Toma, H. S.; Wosiacki, S. R.; Ferrante, M.
Publisher
Universidad Nacional Mayor de San Marcos, Lima, Peru
Citation
Revista de Investigaciones Veterinarias del Perú (RIVEP), 2021, 32, 1,
Abstract

Background: Otitis externa is a common problem in small animal practice. Compliance with daily treatment is a major cause of treatment failure. The hypothesis tested is that a novel otic gel applied to the ear canal twice with a one-week interval is as efficacious as a daily otic suspension in the...

Author(s)
King, S. B.; Doucette, K. P.; Seewald, W.; Forster, S. L.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 307, pp (11 October 2018)
Abstract

Objective: To evaluate the efficacy and safety of a new, single-administration Otic Solution containing florfenicol, terbinafine and mometasone furoate for the treatment of canine otitis externa (OE). Design: The clinical efficacy and safety study was a multicentre, controlled, masked and...

Author(s)
Blake, J.; Keil, D.; Kwochka, K.; Palma, K.; Schofield, J.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record Open, 2017, 4, 1, pp e000219
Abstract

Florfenicol (FF) is a novel animal-specific amidohydrin broad-spectrum antibiotic. However, its aqueous solubility is extremely poor, far below the effective dose required for veterinary clinic. Thus, FF is often used in large doses, which significantly limits its preparation and application. To...

Author(s)
Fan GuoQing; Zhang Li; Shen Yun; Shu Gang; Yuan ZhiXiang; Lin JuChun; Zhang Wei; Peng GuangNeng; Zhong ZhiJun; Yin LiZi; Fu HuaLin
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2019, 9, 1, pp 16739
AbstractFull Text

Florfenicol is a synthetic broad-spectrum antibiotic used to treat infectious diseases in veterinary medicine. Limited information is available on the pharmacokinetics and bioavailability of florfenicol in dogs. This study was conducted in six healthy dogs to determine the bioavailability and...

Author(s)
Bİrdane, Y. O.; Birdane, F. M.
Publisher
Czech Academy of Agricultural Sciences, Prague, Czech Republic
Citation
Veterinární Medicína, 2015, 60, 6, pp 323-329
Abstract

Urinary tract infections (UTIs), many of which are caused by bacterial pathogens, are some of the most common infections in dogs. To effectively treat UTIs, it is important to identify the predominant bacterial pathogens and their susceptibility to antimicrobial agents. In this study, we collected...

Author(s)
Yu ZhuoLing; Wang Yao; Chen YanYun; Huang Min; Wang Yang; Shen ZhangQi; Xia ZhaoFei; Li GeBin
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2020, 241, pp 108540
Abstract

Background: Treatment of infected otitis externa (OE) relies on the topical application of specific formulations that most often contain an antibiotic, an antifungal and a glucocorticoid. This study is to report the results of a randomized, placebo-controlled field trial evaluating the efficacy and ...

Author(s)
Forster, S. L.; Real, T.; Doucette, K. P.; King, S. B.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 262, pp (31 August 2018)

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