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Abstract

Background: Famotidine is sometimes administered as a continuous rate infusion (CRI) to treat gastrointestinal ulceration in critically ill dogs. However, clinical studies have not evaluated the efficacy of a famotidine CRI in dogs. Hypothesis/Objectives: To evaluate the efficacy of famotidine at...

Author(s)
Hedges, K.; Odunayo, A.; Price, J. M.; Hecht, S.; Tolbert, M. K.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2019, 33, 5, pp 1988-1994
Abstract

Background: Famotidine is an acid suppressant commonly administered to dogs. Prolonged famotidine use in people results in decreased efficacy, but the effect in dogs is unknown. Hypothesis/Objectives: To compare the effect of repeated oral administration of famotidine or placebo on intragastric pH...

Author(s)
Tolbert, M. K.; Graham, A.; Odunayo, A.; Price, J.; Steiner, J. M.; Newkirk, K.; Hecht, S.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 1, pp 117-123
Abstract

Background: Upper gastrointestinal (GI) ulceration and bleeding in critically ill dogs can cause severe anemia and increase morbidity. Acid suppressants using proton pump inhibitors or histamine-2 receptor blockers administered IV is commonly recommended. Hypothesis/Objectives: To evaluate the...

Author(s)
Kuhl, A.; Odunayo, A.; Price, J.; Hecht, S.; Marshall, K.; Steiner, J.; Tolbert, M. K.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 2, pp 678-683
Abstract

Background: Famotidine is commonly administered to cats. Prolonged famotidine administration results in decreased efficacy in humans, dogs, and cows, but the long-term effects in cats are unknown. Objectives: To compare the effect of 2 oral administration frequencies of famotidine, twice daily...

Author(s)
Golly, E.; Odunayo, A.; Daves, M.; Vose, J.; Price, J.; Hecht, S.; Steiner, J. M.; Hillsman, S.; Tolbert, M. K.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2019, 33, 2, pp 544-550
Abstract

Background: Omeprazole and famotidine both reduce severity of exercise-induced gastritis, but administering famotidine is easier than administering omeprazole during racing competition. Hypothesis: Famotidine is more efficacious than no treatment in reducing severity of exercise-induced gastritis;...

Author(s)
Williamson, K. K.; Willard, M. D.; Payton, M. E.; Davis, M. S.
Publisher
Blackwell Publishing Ltd, Oxford, UK
Citation
Journal of Veterinary Internal Medicine, 2010, 24, 2, pp 285-288
Abstract

Background: The duration of antacid-induced hypergastrinemia after cessation of administration of omeprazole and famotidine apparently has not been determined in dogs. Hypothesis: That serum gastrin will return to basal concentrations by 7 days after cessation of famotidine or omeprazole...

Author(s)
Parente, N. L.; Olivier, N. B.; Refsal, K. R.; Johnson, C. A.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2014, 28, 5, pp 1465-1470
Abstract

Background: Short-term intravenous co-administration of famotidine and pantoprazole is used by some veterinarians to treat gastrointestinal bleeding in critically ill dogs. However, clinical studies have not evaluated the efficacy of combination acid suppressant treatment in dogs....

Author(s)
Tolbert, M. K.; Odunayo, A.; Howell, R. S.; Peters, E. E.; Reed, A.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2015, 29, 2, pp 556-560
Abstract

Fanconi syndrome is a renal proximal tubulopathy characterized by excessive urinary loss of glucose, amino acids, several electrolytes, and bicarbonate. Here, we report the case of transient Fanconi syndrome in a dog following administration of firocoxib, cefadroxil, tramadol, and famotidine. A 10...

Author(s)
Ahn JinOk; Kim SangMin; Song WooJin; Ryu MinOk; Li Qiang; Chung JinYoung; Youn HwaYoung
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2019, 55, 6, pp 323-327
Abstract

Background: In people, serum gastrin concentrations increase in response to administration of H2 receptor antagonists, but the effect of famotidine administration on serum gastrin concentrations has not been evaluated in dogs. Objectives: To determine if serum gastrin concentrations increase in...

Author(s)
Mordecai, A.; Sellon, R. K.; Mealey, K. L.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2011, 25, 6, pp 1248-1252
Abstract

Background: Serum gastrin concentration can help diagnose gastrinomas in dogs if >3-10× the upper reference limit (URL), but antisecretory therapy and other conditions can also cause hypergastrinemia. Effects of antisecretory therapy (famotidine or ranitidine, omeprazole) on serum gastrin...

Author(s)
Heilmann, R. M.; Berghoff, N.; Grützner, N.; Parnell, N. K.; Suchodolski, J. S.; Steiner, J. M.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 321, pp (7 November 2017)

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