Canine cutaneous lupus erythematosus is recognised in a variety of different forms. The most common chronic form of the disease is the classical facial dominant form, discoid lupus erythematosus. In addition, other chronic variants that have been described include mucocutaneous lupus erythematosus, ...

Background: The treatment of canine chronic cutaneous lupus erythematosus (CCLE) variants generally requires immunosuppression, which often results in potentially severe adverse effects. Janus kinase inhibitors, like oclacitinib, might be a valuable treatment option due to their rapid inhibition of ...

This review discusses the different subtypes of cutaneous canine lupus sensu stricto that share a common histopathological pattern. The most frequent type of cutaneous canine lupus sensu stricto in the dog is localized discoid lupus erythematosus. Other variants are generalized discoid lupus ...

Canine cutaneous lupus erythematosus is recognised in a variety of different forms. The most common chronic form of the disease is the classical facial dominant form, discoid lupus erythematosus. In addition, other chronic variants that have been described include mucocutaneous lupus erythematosus, ...

Cutaneous lupus erythematosus (CLE) is an autoimmune, chronic-relapsing disease that can present as an isolated skin disease or as a manifestation within the spectrum of systemic lupus erythematosus. The pathogenesis of CLE is multifactorial and involves genetic predisposition, environmental...

Cutaneous lupus erythematosus (CLE) in humans encompasses multiple subtypes that exhibit a wide array of skin lesions and, in some cases, are associated with the development of systemic lupus erythematosus (SLE). We investigated dogs with exfoliative cutaneous lupus erythematosus (ECLE), a ...

A specific group of skin diseases in dogs consists of hereditary skin diseases, which include primary seborrhea, ichthyosis, hereditary nasal parakeratosis, dermatomyositis, congenital alopecia, cutaneous mucinosis, dermoid sinus, lethal acrodermatitis, acral mutilation syndrome, ichthyosiform...

Both lupus erythematosus (LE) and pemphigus foliaceus are rare autoimmune diseases in dogs. Pathogenetically, both diseases are based on the formation of autoantibodies, which in lupus are anti-nuclear antibodies (ANA). In pemphigus, on the other hand, the autoantibodies are directed against cell...

Since the first description of discoid lupus erythematosus (LE) in two dogs in 1979, the spectrum of canine cutaneous lupus erythematosus (CLE) variants has expanded markedly. In this review, we first propose an adaptation of the Gilliam-Sontheimer classification of CLE for dogs. We then review the ...

Background: Immune-modulating drugs show limited therapeutic efficacy in canine exfoliative cutaneous lupus erythematosus (ECLE); over half of ECLE dogs are eventually euthanized for their lack of response to therapy. Objective: To describe a case of generalized ECLE in a dog in which mycophenolate ...