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Abstract

Background: Epidermolysis bullosa (EB) is a hereditary heterogeneous group of mechanobullous disorders caused by mutations in several structural skin proteins observed in both humans and animals. In this work, we report the incidence and the genetic trend of the junctional epidermolysis bullosa...

Author(s)
Frattini, S.; Polli, M.; Cortellari, M.; Negro, A.; Bionda, A.; Riva, J.; Rizzi, R.; Marelli, S.; Crepaldi, P.
Publisher
Wiley, Chichester, UK
Citation
Veterinary Record Open, 2021, 8, e15,
Abstract

Epidermolysis bullosa (EB) is a group of blistering disorders that includes several subtypes, classified according to their level of cleavage. Typical clinical signs are blisters and erosions resulting from minimal trauma. The disease has been described in many mammalian species and pathogenic...

Author(s)
Kiener, S.; Mauldin, E. A.; Jagannathan, V.; Casal, M. L.; Leeb, T.
Publisher
Wiley, Oxford, UK
Citation
Animal Genetics, 2022, 53, 6, pp 892-896
Abstract

We investigated three neonatal Basset Hound littermates with lesions consistent with epidermolysis bullosa (EB), a group of genetic blistering diseases. A clinically normal bitch was bred to her grandfather by artificial insemination. Out of a litter of seven puppies, two affected puppies died and...

Author(s)
Garcia, T. M.; Kiener, S.; Jagannathan, V.; Russell, D. S.; Leeb, T.
Publisher
MDPI Publishing, Basel, Switzerland
Citation
Genes, 2020, 11, 12,
Abstract

Epidermolysis bullosa (EB) is a hereditary mechanobullous disease of animals and humans, characterized by an extreme fragility of the skin and mucous membranes. The main feature of EB in humans and animals is the formation of blisters and erosions in response to minor mechanical trauma. ...

Author(s)
Medeiros, G. X.; Riet-Correa, F.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Dermatology, 2015, 26, 1, pp 3-e2
Abstract

Background: Junctional epidermolysis bullosa (JEB) is a group of congenital blistering skin diseases characterized by clefting through the lamina lucida of the basement membrane zone. Objectives: To characterize the clinical and morphological features of a congenital mechanobullous disease in a...

Author(s)
Herrmann, I.; Linder, K. E.; Meurs, K. M.; Friedenberg, S. G.; Cullen, J.; Olby, N.; Bizikova, P.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2021, 32, 4, pp 379-e108
Abstract

Epidermolysis bullosa simplex (EBS) is a hereditary blistering disease affecting the skin and mucous membranes. It has been reported in humans, cattle, buffaloes and dogs, but so far not in cats. In humans, EBS is most frequently caused by variants in the KRT5 or KRT14 genes. Here, we report a case ...

Author(s)
Dettwiler, M.; Leuthard, F.; Bauer, A.; Jagannathan, V.; Lourenço, A. M.; Pereira, H.; Leeb, T.; Welle, M. M.
Publisher
Wiley, Oxford, UK
Citation
Animal Genetics, 2020, 51, 5, pp 829-832
Abstract

In a highly inbred Australian Shepherd litter, three of the five puppies developed widespread ulcers of the skin, footpads, and oral mucosa within the first weeks of life. Histopathological examinations demonstrated clefting of the epidermis from the underlying dermis within or just below the...

Author(s)
Kiener, S.; Laprais, A.; Mauldin, E. A.; Jagannathan, V.; Olivry, T.; Leeb, T.
Publisher
MDPI Publishing, Basel, Switzerland
Citation
Genes, 2020, 11, 9,
Abstract

The group of skin diseases in dogs consists of diseases of various origins, which are typical of very similar clinical symptoms. Differential diagnosis in veterinary dermatology is complicated. Hereditary skin diseases present a specific type of skin diseases that are not frequent and commonly are...

Author(s)
Malinovská, Z.; Conkova, E.
Publisher
Profi Press, s.r.o., Prague, Czech Republic
Citation
Veterinářství, 2021, 71, 9, pp 503-510
Abstract

A specific group of skin diseases in dogs consists of hereditary skin diseases, which include primary seborrhea, ichthyosis, hereditary nasal parakeratosis, dermatomyositis, congenital alopecia, cutaneous mucinosis, dermoid sinus, lethal acrodermatitis, acral mutilation syndrome, ichthyosiform...

Author(s)
Malinovská, Z.; Čonkova, E.
Publisher
Profi Press, s.r.o., Prague, Czech Republic
Citation
Veterinářství, 2021, 71, 8, pp 448-455
Abstract

Background: Epidermolysis bullosa acquisita (EBA) is a rare autoimmune subepidermal blistering disease of dogs and humans. Objectives: Our objectives were to describe clinical phenotypes, histopathology and treatment outcomes of canine EBA. Animals: Twenty dogs diagnosed with EBA based on a...

Author(s)
Bizikova, P.; Linder, K. E.; Wofford, J. A.; Mamo, L. B.; Dunston, S. M.; Olivry, T.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Dermatology, 2015, 26, 6, pp e103

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