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AbstractFull Text

This case report aims to describe how Electrochemotherapy as well as other joint actions such as neoadjuvancy, surgical resections and chemotherapy, have acted in the treatment of a 13-year-old dog diagnosed with Grade III Mastocytoma, a high degree of malignancy. The choice of the best therapy as...

Author(s)
Otero, C. V. L.; Duarte, E. G.; Oliveira, P. P. de; Oliveira, T. E. de; Lima, B. de T. A. R.
Publisher
Pubvet, Maringá, Brazil
Citation
PUBVET, 2021, 15, 3,
Abstract

Mastocytoma is a round cell neoplasm often found in dogs, accounting for 7% to 21% of cutaneous neoplasms. This study aimed to report the clinical and hematological changes in a patient with canine mastocytoma when submitted to chemotherapy and electrochemotherapy. It was attended at the...

Author(s)
Moura, J. A. de; Costa e Silva, M.; Monteiro, C. L. B.; Sousa, N. da C.
Publisher
Federal University of Ceará, Fortaleza, Brazil
Citation
Revista Brasileira de Higiene e Sanidade Animal, 2019, 13, 2, pp 252-265
Abstract

Electrochemotherapy (ECT) and/or gene electrotransfer of plasmid DNA encoding interleukin-12 (GET pIL-12) are effective treatments for canine cutaneous, subcutaneous, and maxillofacial tumors. Despite the clinical efficacy of the combined treatments of ECT and GET, data on parameters that might...

Author(s)
Brloznik, M.; Brezar, S. K.; Boc, N.; Knific, T.; Cemazar, M.; Milevoj, N.; Sersa, G.; Tozon, N.; Pavlin, D.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2021, 7, May,
Abstract

Canine cutaneous squamous cell carcinoma (cSCC) is the most common skin cancer in dogs, and, due to its low metastatic rate, local treatments, such as electrochemotherapy (ECT), promote disease control or even complete remission (CR). This study aimed to evaluate the gene and protein expression of...

Author(s)
Anjos, D. S. dos; Bueno, C.; Magalhães, L. F.; Magalhães, G. M.; Mattos-Junior, E.; Pinto, M. M. R.; Nardi, A. B. de; Brunner, C. H. M.; Leis-Filho, A. F.; Calazans, S. G.; Fonseca-Alves, C. E.
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2019, 9, 1, pp 15819
AbstractFull Text

Background: Electrochemotherapy (ECT) combines the administration of anticancer drugs with the delivery of electric pulses, thus increasing the drug uptake through the cell membranes, resulting in increased efficacy. Aim: The aim of our study was to describe the tolerability and efficacy of ECT...

Author(s)
Valenti, P.; Menicagli, F.; Baldi, A.; Barella, G.; Catalucci, C.; Attorri, V.; Spugnini, E. P.
Publisher
Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya
Citation
Open Veterinary Journal, 2021, 11, 1, pp 100-106
Abstract

The aim of this study was to evaluate the owners' perception of health-related quality of life (HRQoL) of dogs after treatment with electrochemotherapy (ECT) alone or combined with interleukin-12 gene electrotransfer (IL-12 GET) and/or surgery. The owners of 44 dogs with histologically different...

Author(s)
Milevoj, N.; Tozon, N.; Licen, S.; Tratar, U. L.; Sersa, G.; Cemazar, M.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Medicine and Science, 2020, 6, 3, pp 290-298
Abstract

Non-tonsillar squamous cell carcinoma (ntSCC) is a common and locally aggressive oral tumour in dogs. The treatments of choice are currently surgery and radiotherapy. Electrochemotherapy (ECT) is a local ablative anti-tumour technique using electric pulses to enhance the intracellular diffusion of...

Author(s)
Simčič, P.; Lowe, R.; Granziera, V.; Pierini, A.; Torrigiani, F.; Lubas, G.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2020, 18, 3, pp 428-432
AbstractFull Text

Mesenchymal tumors pose a significant clinical challenge, especially when they reach substantial volumes. The authors present a case of inoperable prescapular schwannoma treated with ultrasound assisted electrochemotherapy in a dog. Electrochemotherapy potentiated the efficacy of the antitumor...

Author(s)
Pierluigi Spugnini, E.; Menicagli, F.; Lellis, L. de
Publisher
Edizioni SCIVAC, Cremona, Italy
Citation
Veterinaria (Cremona), 2020, 34, 4, pp 191-194
Abstract

The aim of this study was to evaluate the safety and efficacy of the combination of electrochemotherapy (ECT) with bleomycin and gene electrotransfer (GET) of plasmid encoding canine interleukin 12 (IL-12) for the treatment of canine oral malignant melanoma (OMM). Our focus was to determine the...

Author(s)
Milevoj, N.; Tratar, U. L.; Nemec, A.; Brožič, A.; Žnidar, K.; Serša, G.; Čemažar, M.; Tozon, N.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2019, 122, pp 40-49
AbstractFull Text

Present study includes clinical cases of dogs with malignant superficial tumour irrespective of age, sex and breed. The dogs were divided in three equal groups and were subjected to three different treatment regimens. The dogs in group I and II were treated with doxorubicin hydrochloride @ 30 mg/m2 ...

Author(s)
Neware, A. S.; Akhare, S. B.; Jadhao, P. T.; Upadhye, S. V.; Kamble, M. V.; Kurkure, N. V.
Publisher
College of Veterinary Sciences, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, India
Citation
Haryana Veterinarian, 2019, 58, 1, pp 93-96

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