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Abstract

Background: The American Heartworm Society currently recommends the use of a monthly macrocyclic lactone, a 28-day course of 10 mg/kg doxycycline BID, and the 3-dose protocol of melarsomine dihydrochloride for the treatment of canine heartworm disease. Doxycycline is necessary for the reduction of...

Author(s)
Savadelis, M. D.; Day, K. M.; Bradner, J. L.; Wolstenholme, A. J.; Dzimianski, M. T.; Moorhead, A. R.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2018, 11, 671, pp (27 December 2018)
Abstract

Doxycycline has antiproliferative effects in human lymphoma cells and in murine xenografts. We hypothesized that doxycycline would decrease canine lymphoma cell viability and prospectively evaluated its clinical tolerability in client-owned dogs with spontaneous, nodal, multicentric, substage a,...

Author(s)
Hume, K. R.; Sylvester, S. R.; Borlle, L.; Balkman, C. E.; McCleary-Wheeler, A. L.; Pulvino, M.; Casulo, C.; Zhao JiYong
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, February, pp 25
Abstract

Melarsomine dihydrochloride (Immiticide®, Merial) is the only approved adulticidal drug for the treatment of canine heartworm disease (HWD). However, in cases where arsenical therapy is not possible or is contraindicated, a monthly heartworm preventive along with doxycycline for a 4-week period,...

Author(s)
Kramer, L.; Crosara, S.; Gnudi, G.; Genchi, M.; Mangia, C.; Viglietti, A.; Quintavalla, C.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2018, 254, pp 95-97
Abstract

Twenty-two dogs diagnosed with canine heartworm disease (HWD) were classified into four groups (Class 1 [11 dogs], Class 2 [5 dogs], Class 3 [5 dogs], and Class 4 [1 dog]). Treatment was attempted with oral doxycycline and ivermectin combined with a single injection of melarsomine. The mean...

Author(s)
Ikemizu, T.; Shirahama, J.
Publisher
Japanese Society of Clinical Veterinary Medicine, Tottori, Japan
Citation
Journal of Animal Clinical Medicine, 2017, 26, 1, pp 16-23
Abstract

Canine monocytic ehrlichiosis (CME) is an important hemoprotozoan disease of dogs associated with anemia, leucopenia, and thrombocytopenia. The present study was conducted with the aim of assessing the status of oxidative/nitrosative stress and apoptosis in naturally occurring cases of chronic ...

Author(s)
Mahadappa Priyanka; Sahadeb Dey; Meeta Saxena
Publisher
Springer Science + Business Media, London, UK
Citation
Comparative Clinical Pathology, 2019, 28, 1, pp 215-224
Abstract

Background: Doxycycline has been considered the first drug of choice for treating Wolbachia, a member of the Rickettsiaceae, which has a symbiotic relationship with filarial worms, including heartworms. Wolbachia, is susceptible to tetracyclines, which have been used as adjunctive treatments for...

Author(s)
Papich, M. G.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2017, 10, Suppl. 2, pp (9 November 2017)
AbstractFull Text

Canine ehrlichiosis is caused by Ehrlichia canis and transmitted by Rhipicephalus sanguineus. A nine month old male Dachshund dog weighing 8.5 Kg was presented to the TVCC, Bihar Veterinary College, Patna with complaint of pyrexia, anorexia, melena and tick infestation. Blood smear examination...

Author(s)
Anil Kumar; Pallav Shekhar; Singh, G. D.; Ramesh Tiwary; Ajit Kumar
Publisher
Indian Society for Advancement of Canine Practice, Lucknow, India
Citation
Indian Journal of Canine Practice, 2019, 11, 1, pp 25-26
Abstract

Background: Using the US Clinical and Laboratory Standards Institute (CLSI) human tetracycline breakpoints to predict minocycline and doxycycline susceptibility of Staphylococcus pseudintermedius (SP) isolates from dogs is not appropriate because they are too high to meet...

Author(s)
Hnot, M. L.; Cole, L. K.; Lorch, G.; Papich, M. G.; Rajala-Schultz, P. J.; Daniels, J. B.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Dermatology, 2015, 26, 5, pp e71
AbstractFull Text

Fifty (50) microscopically diagnosed Babesia positive dogs were randomly divided into five treatment groups (B, C, D, E and F) with intention to comparatively evaluate the therapeutic efficacy of single drugs with combination therapy. Parameters were compared with healthy control group A. The dogs...

Author(s)
Baishya, B. C.; Phukan, A.; Mahato, G.; Goswami, S.; Kakati, P.
Publisher
Intas Pharmaceuticals Ltd, Ahmedabad, India
Citation
Intas Polivet, 2018, 19, 2, pp 249-253
Abstract

Background: The objective of heartworm treatment is to improve the clinical condition of the patient and to eliminate pre-cardiac, juvenile, and adult worm stages with minimal complications. Pulmonary thromboembolisms are an inevitable consequence of worm death and can result in severe pulmonary...

Author(s)
Nelson, C. T.; Myrick, E. S.; Nelson, T. A.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2017, 10, Suppl. 2, pp (9 November 2017)

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