Insulin deficiency diabetes (IDD) in dogs is an endocrine disease similar to human type 1 diabetes. There are breeds more commonly affected, such as Yorkshire Terrier and Samoyed, suggesting an underlying genetic component. However, the genetic basis for canine diabetes mellitus (DM) is not fully...

Samoyeds and Australian Terriers are the 2 dog breeds at highest risk (>10-fold) for diabetes mellitus in the United States. It is unknown if the insulin (INS) gene is involved in the pathophysiology of diabetes in Samoyeds and Australian Terriers. It was hypothesized that the INS gene region...

This study was preformed to determine the effects of some diseases on acute phase protein and some hematobiochemical parameters in dogs. Our study was preformed on 91 dogs. These dogs aged from 4-24 months old and weighted from 12-15 kg. According to clinical signs and physical examinations, dogs...

Diabetes mellitus is an endocrine disorder that is the result of a decreased ability of the body to produce or react to insulin, which leads to an abnormal metabolism of carbohydrates and increased levels of glucose in the blood and urine. This thesis compares the differences regarding etiology and ...

Background: Diabetes mellitus (DM) often leads to dangerous thromboembolic complications in humans. DM is also a relatively common endocrinopathy of dogs. There is scarce information regarding procoagulant and anticoagulant plasma indicators in this disease. The aim of the study was to evaluate the ...

Tissue fibrosis as complication of diabetes mellitus is known in humans. Because TGF-β1 induces fibrosis and is elevated in humans suffering from diabetes mellitus we measured this growth factor in serum of dogs with diabetes mellitus and compared it with healthy dogs and those with fibrotic...

In dogs with naturally occurring, insulin-dependent (C-peptide negative) diabetes mellitus, impairment of glucagon responses is not due to generalized impairment of α-cell function. Loss of tonic inhibition of glucagon secretion by insulin is not sufficient, by itself, to produce loss of the...

Canine and feline obesity rates have reached pandemic proportions and are similar to those in humans, with approximately 30%-40% of dogs and cats being overweight to obese. Obesity has been associated with other health problems, including osteoarthritis, renal disease, skin disease, insulin...

OBJECTIVE To evaluate the performance of 2 assays for measurement of serum fructosamine (SF) and glycated hemoglobin (HbA1c) values in dogs and to compare the usefulness of the 2 glycated proteins for assessment of glycemic control in dogs with diabetes mellitus (DM). SAMPLE Blood samples from 40...

Diabetes mellitus (DM) is a common disorder in dogs, which is not monitored very effectively or diagnosed on time. Detection of some biochemical abnormalities in the diabetes pathogenesis ever since the beginning of disease suspicion remains an important goal concerning the early therapeutic...