The current study was conducted to determine various haemato-biochemical alterations and histopathological changes in addition to evaluation of insulin monotherapy, insulin plus some herbal therapy including Fenugreek (Trigonella foenum-graecum), Garlic and Black seeds (Nigella sativa) as well as...
Author(s)
Abdullaziz, I. A.; Ismael, M. M.; Metwally, A. M.; El-Sayed, M. S.; Elblehi, S. S.; El-Saman, A. E. R. M.
Publisher
Faculty of Veterinary Medicine, Alexandria University, Behira, Egypt
Citation
Alexandria Journal of Veterinary Sciences, 2022, 73, 1, pp 111-127
Diabetes mellitus (DM) is a metabolic disorder characterized by persistent hyperglycemia. Although most diabetic dogs have type 1 diabetes mellitus, type 2 diabetes mellitus can also especially afflict those who are obese. This study aims to investigate how nutritional management can help in the...
Author(s)
Massari, C. H. de A. L.; Freires, L. R.; Costa, H. L. R.; Oyama, S. M. R.; Saad, F. M. de O. B.
Publisher
Pubvet, Maringá, Brazil
Citation
PUBVET, 2022, 16, 1,
Canine diabetes has been considered a potential model of human type 1 diabetes (T1D), however the detection of autoantibodies common in humans with T1D in affected dogs is inconsistent. The aim of this study was to compare autoantibody responses in diabetic and healthy control dogs using a novel...
Author(s)
O'Kell, A. L.; Shome, M.; Qiu Ji; Williams, S.; Chung Yunro; Labaer, J.; Atkinson, M. A.; Wasserfall, C.
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2022, 12, 2,
Mesenchymal stem cells (MSCs) possess regenerative and immunomodulatory properties and can control the immune dysregulation that leads to β-cell destruction. Stem-cell transplantation could thus manage insulin-dependent diabetes mellitus (IDDM) in dogs. In this pilot study, we aimed to assess ...
Author(s)
Rhew SungYong; Park SuMin; Li Qiang; An JuHyun; Chae HyungKyu; Lee JungHwa; Ahn JinOk; Song WooJin; Youn HwaYoung
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2021, 83, 4, pp 592-600
The year 2021 marked the centenary of the isolation of a therapeutic form of insulin and its successful use in dogs. This was a landmark moment that subsequently and rapidly led to the commercial manufacture of insulin for use in humans. The impact of insulin was almost miraculous as those destined ...
Author(s)
Shiel, R. E.; Mooney, C. T.
Publisher
BioMed Central Ltd, London, UK
Citation
Canine Medicine and Genetics, 2022, 9, 1, pp (14 February 2022)
Background: Canine diabetes mellitus has mostly been studied in northern European, Australian and American populations, whereas other regions have received less attention. Objectives: We evaluated the epidemiological, clinical and histopathological features of diabetic dogs in Gran Canaria, Spain....
Author(s)
Brito-Casillas, Y.; Melián, C.; Holder, A.; Wiebe, J. C.; Navarro, A.; Quesada-Canales, Ó.; Expósito-Montesdeoca, A. B.; Catchpole, B.; Wägner, A. M.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Medicine and Science, 2021, 7, 4, pp 1071-1081
Canine Diabetes Mellitus (CDM) is represented as a group of autoimmune metabolic diseases of multifactorial etiology. In CDM there is a relative or absolute deficiency of insulin that leads to a failure of the cells to obtain and use glucose. Are most cases, diagnosed dogs will be insulin dependent ...
Author(s)
Batista, K. A. S.; Santos, C. B. dos; Shihadeh, M. S. S.; Toledo, D. R. de; Landa, E. D.; Mendes, P. F.
Publisher
Pubvet, Maringá, Brazil
Citation
PUBVET, 2021, 15, 10,
Background: Diabetes mellitus (DM) and hypothyroidism are common canine endocrinopathies. Both canine DM and primary hypothyroidism are assumed to originate from autoimmune destruction of the respective endocrine glands and have been associated with the major histocompatibility complex (MHC) gene...
Author(s)
Ringstad, N. K.; Lingaas, F.; Thoresen, S. I.
Publisher
BioMed Central Ltd, London, UK
Citation
Canine Medicine and Genetics, 2022, 9, 9,
Insulin deficiency diabetes (IDD) in dogs is an endocrine disease similar to human type 1 diabetes. There are breeds more commonly affected, such as Yorkshire Terrier and Samoyed, suggesting an underlying genetic component. However, the genetic basis for canine diabetes mellitus (DM) is not fully...
Author(s)
Sanz, C. R.; Sevane, N.; Pérez-Alenza, M. D.; Valero-Lorenzo, M.; Dunner, S.
Publisher
Wiley, Oxford, UK
Citation
Animal Genetics, 2021, 52, 3, pp 333-341
Background: Canine diabetes mellitus (DM) is a common endocrine disease in domestic dogs. A number of pathological mechanisms are thought to contribute to the aetiopathogenesis of relative or absolute insulin deficiency, including immune-mediated destruction of pancreatic beta cells. DM risk varies ...
Author(s)
Denyer, A. L.; Massey, J. P.; Davison, L. J.; Ollier, W. E. R.; Catchpole, B.; Kennedy, L. J.
Publisher
BioMed Central Ltd, London, UK
Citation
Canine Medicine and Genetics, 2020, 7, 15, pp (31 October 2020)