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Abstract

Most canine deafness is linked to white pigmentation caused by the piebald locus, shown to be the gene MITF (melanocyte inducing transcription factor), but studies have failed to identify a deafness cause. The coding regions of MITF have not been shown to be mutated in deaf dogs, leading us to...

Author(s)
Kelly-Smith, M.; Strain, G. M.
Publisher
Elsevier, Oxford, UK
Citation
Veterinary and Animal Science, 2020, 9,
Abstract

Background The calculation of demographic measures is a useful tool for evaluating the genomic architecture of dog breeds and enables ranking dog breeds in terms of genetic diversity. To achieve this for the German Dalmatian dog population, 307 purebred animals of this breed were genotyped on the...

Author(s)
Vasiliadis, D.; Metzger, J.; Distl, O.
Publisher
BioMed Central Ltd, London, UK
Citation
Canine Medicine and Genetics, 2020, 7, 3, pp (26 March 2020)
Abstract

Background: During routine diagnostic BAER testing of dogs of various breeds for private owners at the Western College of Veterinary Medicine in Saskatoon, it became evident that some individual dogs developed hearing loss as adults. Although inherited congenital deafness has been widely reported...

Author(s)
Schmutz, S. M.
Publisher
BioMed Central Ltd, London, UK
Citation
Canine Genetics and Epidemiology, 2014, 1, 6, pp (28 May 2014)
Abstract

Although deafness can be acquired throughout an animal's life from a variety of causes, hereditary deafness, especially congenital hereditary deafness, is a significant problem in several species. Extensive reviews exist of the genetics of deafness in humans and mice, but not for deafness in...

Author(s)
Strain, G. M.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2015, 2, September, pp 29
Abstract

Background: Congenital sensorineural deafness (CSD) is the most common type of deafness in Dalmatian dogs. Objectives: To use results of CSD screening in Dalmatian dogs in the United Kingdom in genetic analysis and to determine any changes in the prevalence of CSD in this breed over time. Animals:...

Author(s)
Lewis, T.; Freeman, J.; Risio, L. de
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 4, pp 1524-1531
Abstract

The objective of this study was to evaluate any otopathologic changes in temporal bone specimens from dogs with deafness related to cochleosaccular (Scheibe) dysplasia (CSD). We used the canine temporal bone collections of the Otopathology Laboratory at the University of Minnesota and of the...

Author(s)
Keskin, N.; Albasan, H.; Sancak, I. G.; Paparella, M. M.; Cureoglu, S.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2019, 83, 1, pp 11-16
Abstract

Accurate assessment of canine hearing is essential to decrease the incidence of hereditary deafness in predisposed breeds and to substantiate hearing acuity. The Brainstem Auditory Evoked Response (BAER) is a widely accepted, objective test used in humans and animals for estimation of hearing...

Author(s)
Kemper, D. L.; Scheifele, P. M.; Clark, J. G.
Publisher
Elsevier, New York, USA
Citation
Physiology & Behavior, 2013, 110/111, pp 190-197
Abstract

Background - Congenital sensorineural deafness is an inherited condition found in many dog breeds, including Australian Stumpy-tail Cattle Dogs (ASCD). This deafness is evident in young pups and may affect one ear (unilateral) or both ears (bilateral). The genetic locus/loci involved is unknown for ...

Author(s)
Sommerlad, S.; McRae, A. F.; McDonald, B.; Johnstone, I.; Cuttell, L.; Seddon, J. M.; O'Leary, C. A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2010, No.October, pp e13364
Abstract

Genetic disease testing programmes are used in domestic animal breeds to guide selective breeding with the aim of reducing disease prevalence. We assessed the change in the prevalence of canine congenital hereditary sensorineural deafness (CHSD) in litters of Australian Cattle Dogs following the...

Author(s)
Sommerlad, S. F.; Morton, J. M.; Johnstone, I.; O'Leary, C. A.; Seddon, J. M.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Animal Genetics, 2014, 45, 6, pp 855-862
Abstract

Background: Congenital hereditary sensorineural deafness (CHSD) occurs in many dog breeds, including Australian Cattle Dogs. In some breeds, CHSD is associated with a lack of cochlear melanocytes in the stria vascularis, certain coat characteristics, and potentially, abnormalities in...

Author(s)
Sommerlad, S. F.; Morton, J. M.; Haile-Mariam, M.; Johnstone, I.; Seddon, J. M.; O'Leary, C. A.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2012, 8, 202, pp (29 October 2012)

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