Cutaneous mucinosis is a primary idiopathic dermatopathy that occurs in dogs of the Shar pei breed, characterized by excessive deposition of mucin in the dermis that leads to the presentation of skin folds, and in more severe cases the formation of vesicles or blisters. Hyaluronic acid has been...

Cutaneous mucinosis affects primarily shar-pei dogs. Hyaluronic acid (HA) is considered to be the main component of mucin and CD44 is the major cell surface receptor of HA, necessary for its uptake and catabolism. The aims of this study were to identify the composition of the mucin in cutaneous ...

A specific group of skin diseases in dogs consists of hereditary skin diseases, which include primary seborrhea, ichthyosis, hereditary nasal parakeratosis, dermatomyositis, congenital alopecia, cutaneous mucinosis, dermoid sinus, lethal acrodermatitis, acral mutilation syndrome, ichthyosiform...

Cutaneous mucinosis is a disorder of dermal connective tissue in which excessive mucin accumulates in the skin. Secondary mucinosis may be presented in hypothyroidism, variety of inflammatory skin diseases including allergic and eosinophilic dermatitis, pyoderma and lupus erythematosus as well as...

Cutaneous mucinosis is a cutaneous disorder described in humans, dogs, and rarely cats but never reported in birds. Twenty-six brown egg-laying chickens between ages 43 and 46 weeks had a history of feather loss, scaly, dry skin, weight loss, and decreased egg production. Microscopic findings in...

The Chinese shar-pei dog is known for its distinctive feature of wrinkled and thickened skin, defined as primary or hereditary cutaneous mucinosis. In a recent report, we identified the mucinous material deposited in the shar-pei skin as the polysaccharide hyaluronan (HA). In the present work, the...

Shar pei dogs are known for the distinctive feature of thick, wrinkled skin as a consequence of high dermal mucin content. Excessive dermal deposition of mucinous substance leading to severe skin folding, and/or to the more severe vesicular form characterized by dermal vesicles or bullae, is highly ...

A neutered male Shar-Pei dog with a cutaneous growth on the left anterior metacarpus, bleeding for the past two days, was presented for treatment in the clinic. Histopathology of pedunculated, moderately well-demarcated, non-capsulated mass revealed proliferative cells exhibiting scanty...

Shar pei dogs are known for the distinctive feature of thick, wrinkled skin as a consequence of high dermal mucin content. Excessive dermal deposition of mucinous substance leading to severe skin folding, and/or to the more severe vesicular form characterized by dermal vesicles or bullae, is highly ...

The group of skin diseases in dogs consists of diseases of various origins, which are typical of very similar clinical symptoms. Differential diagnosis in veterinary dermatology is complicated. Hereditary skin diseases present a specific type of skin diseases that are not frequent and commonly are...