Color dilution alopecia (CDA) is a dermatopathy observed exclusively in animals having a diluted coat color. In dogs, color dilution occurs as a result of a single-nucleotide variation (SNV) c.-22G>A in the melanophilin gene. We standardized a PCR-restriction-fragment length polymorphism (PCR-RFLP) ...

Background: Dobermann dogs are predisposed to colour dilution alopecia and follicular dysplasia. Limited information is available regarding the trichographic features of normal canine hair shafts, including those from Dobermanns, with no studies of inter-observer agreement for canine trichographic...

The alopecia by color dilution is a rare dermatological disease that occasionally occurs in black coat and is conserved in yellow coat, and mainly accommodates dogs with dark coat, unknown etiology. It is known what type of melanin hair is in the hair. This paper reports a case of color dilution ...

Color dilution alopecia is characterized by follicular dysplasia that leads to alopecia characterized by an abnormal distribution of melanin in the hair. There are few reports of mixed breed dogs and the diagnosis can be reached based on trichogramma and confirmed by histopathological evaluation....

Mutant color alopecia is an ectodermical defection of color dilution, characterized by partial alopecia, dry, shine-less hair, and peeling and papule. Melanization damages also occur on the cortical structure of the affected hair. The animals affected have big melanin grains with irregular shape on ...

Identification of genetic mutations causing disease is helpful in breeding programmes aimed at enhancing the qualities of a breed. The ceský fousek (CF), also known as the Bohemian wirehaired pointing griffon, is a versatile hunting dog that dates back to the 14th century. Because no genetic...

Melanocytes transfer the melanosomes to the neighboring keratinocytes via dendritic projections, however, mechanism of melanin transfer in canine hair follicles have not been fully elucidated. In this study, we investigated the ultrastructure of hair follicles, focusing on melanin transfer in a...

The canine melanophilin gene (MLPH) is one of three the most studies genes which is associate with coat color dilution in several breeds of dog which is characterized by a specific pigmentation phenotype. The coat color dilution is inherited as a Mendelian autosomal recessive trait and in some...

The squamous cell carcinoma is a malignant tumor associated to little haired body areas which are exposed to sunlight. Alopecia by dilution of color is a relatively uncommon skin disease in dogs, characterized by loss of coat in the color-diluted areas of the skin. The aim of this study is to...

Phaeohyphomycoses are recognized as opportunistic fungal infections caused by several genera of melanin-pigmented moulds (dematiaceous fungi) which are ubiquitous saprophytic agents found in soil, water and decaying vegetable matter. These infections are usually acquired by direct traumatic...