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AbstractFull Text

Two cases of granulomatous colitis in two French bulldogs were found to be unresponsive to fluoroquinolones. The granulomatous colitis diagnosis was made on the basis of PAS-positive histiocytes in the lamina propria of the colonic mucosa in biopsy samples taken at colonoscopy. Remission of ...

Author(s)
Lucena, R.; Novales, M.; Ginel, P. J.
Publisher
Czech Academy of Agricultural Sciences, Prague, Czech Republic
Citation
Veterinární Medicína, 2017, 62, 5, pp 292-294
Abstract

A two-year-old female French bulldog was presented for chronic large bowel diarrhoea. The dog had been suspected to have granulomatous colitis, but no improvement was noted with enrofloxacin treatment. Diagnosis was confirmed by histology and fluorescent in situ hybridisation. Isolated Escherichia...

Author(s)
Mueller, M.; Dahlem, D. P.; Henrich, M.; Neiger, R.; Schmitz, S.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record Case Reports, 2016, 4, 1, pp e000296
Abstract

Case summary: This report describes a 4-year-old cat with chronic intermittent haematochezia and faecal incontinence of 7 months' duration. Investigation revealed severe colonic multifocal mucosal ulcerations and infiltration of the mucosal lamina propria by large numbers of periodic...

Author(s)
Leal, R. O.; Simpson, K.; Fine, M.; Husson, J. C.; Hernandez, J.
Publisher
Sage Publications Ltd, London, UK
Citation
Journal of Feline Medicine and Surgery Open Reports, 2017, 3, 2, pp 2055116917731168
Abstract

Case summary: A 10-year-old castrated male domestic shorthair cat presented with a 6 month history of diarrhoea that responded poorly to medical treatment. Ultrasonography revealed moderate thickening of the colonic wall (4.8 mm) and right colic and jejunal lymphadenomegalies. Endoscopic...

Author(s)
Matsumoto, I.; Nakashima, K.; Morita, H.; Kasahara, K.; Kataoka, O.; Uchida, K.
Publisher
Sage Publications Ltd, London, UK
Citation
Journal of Feline Medicine and Surgery Open Reports, 2019, 5, 1, pp 14-2055116919836537
Abstract

The domestic dog is becoming an increasingly valuable model species in medical genetics, showing particular promise to advance our understanding of cancer and orthopaedic disease. Here we undertake the largest canine genome-wide association study to date, with a panel of over 4,200 dogs genotyped...

Author(s)
Hayward, J. J.; Castelhano, M. G.; Oliveira, K. C.; Corey, E.; Balkman, C.; Baxter, T. L.; Casal, M. L.; Center, S. A.; Fang MeiYing; Garrison, S. J.; Kalla, S. E.; Korniliev, P.; Kotlikoff, M. I.; Moise, N. S.; Shannon, L. M.; Simpson, K. W.; Sutter, N. B.; Todhunter, R. J.; Boyko, A. R.
Publisher
Nature Publishing Group, London, UK
Citation
Nature Communications, 2016, 7, 1, pp 10460
Abstract

Background: French Bulldogs develop a form of granulomatous colitis (GC) with histopathological resemblance to GC of Boxer dogs (GCB). GCB is associated with mucosally invasive Escherichia coli whose eradication correlates with clinical remission. Hypothesis/Objectives: To characterize the clinical ...

Author(s)
Manchester, A. C.; Hill, S.; Sabatino, B.; Armentano, R.; Carroll, M.; Kessler, B.; Miller, M.; Dogan, B.; McDonough, S. P.; Simpson, K. W.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2013, 27, 1, pp 56-61
Abstract

Background: The optimal medical treatment for chronic enteropathy (CE) in dogs and cats is controversial. Sequential treatment using diet, antimicrobials, and immunosuppressive drugs is the most common strategy used by clinicians. Objectives: To review the evidence for the effectiveness of dietary, ...

Author(s)
Makielski, K.; Cullen, J.; O'Connor, A.; Jergens, A. E.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2019, 33, 1, pp 11-22
Abstract

In dogs with symptomatic or asymptomatic leishmaniosis, Leishmania infantum appears to induce a mixed Th1/Th2 immune response that in the sick dog may eventually result in tissue damage via different pathomechanisms, notably granulomatous inflammation (eg, nodular dermatitis, osteomyelitis), immune ...

Author(s)
Koutinas, A. F.; Koutinas, C. K.
Publisher
American College of Veterinary Pathologists Inc., Lawrence, USA
Citation
Veterinary Pathology, 2014, 51, 2, pp 527-538
Abstract

Granulomatous colitis (GC) is a rare, breed-specific inflammatory bowel disease of young Boxer dogs. GC has been refractory to treatment and associated with high mortality rates, but culture-independent molecular analysis has transformed therapy and prognosis by uncovering a correlation between GC...

Author(s)
Craven, M.; Mansfield, C. S.; Simpson, K. W.
Publisher
W.B. Saunders, Philadelphia, USA
Citation
Veterinary Clinics of North America, Small Animal Practice, 2011, 41, 2, pp 433-445
Abstract

The colon plays an important role in the conservation of water and electrolytes and is the major site of faecal storage until expulsion is necessary. With regard to digestion and metabolism, the colon is often underestimated: the colonic bacterial flora plays an important role in the fermentation...

Author(s)
Burgener, I. A.
Publisher
Verlag M. & H, Schaper Gmbh, Hannover, Germany
Citation
Kleintierpraxis, 2013, 58, 7, pp 362-377

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