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Abstract

Objective: To determine the noninferior postoperative analgesic efficacy of cimicoxib compared to buprenorphine following elective ovariohysterectomy in healthy bitches. Study design: Prospective, randomized, blinded, controlled clinical trial. Animals: A total of 63 healthy dogs. Methods: To...

Author(s)
Bustamante, R.; Daza, M. A.; Canfrán, S.; García, P.; Suárez, M.; Trobo, I.; Gómez de Segura, I. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2018, 45, 4, pp 545-556
AbstractFull Text

Background: Cimicoxib is a coxib recently licensed in Europe for pain and inflammation associated with osteoarthritis (OA), and the management of perioperative pain due to orthopaedic or soft tissue surgery. Purpose: This prospective study was to complete the product information for the end users...

Author(s)
Murrell, J.; Grandemange, E.; Woehrle, F.; Menard, J.; White, K.
Publisher
Scientific Research Publishing, Irvine, USA
Citation
Open Journal of Veterinary Medicine, 2014, 4, 5, pp 78-90
Abstract

Background: Cimicoxib is a new coxib anti-inflammatory drug for use in the dog. To determine a preclinical dosage regimen for cimicoxib in dog, a reversible model of kaolin-induced paw inflammation was used. Dosage regimens were established using pharmacokinetic/pharmacodynamic (PK/PD) modeling...

Author(s)
Elisabeth, J. C.; Marc, S.; Frederique, W.; Mathieu, F.; Herve, L. P.; Pierre-Louis, T.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2013, 9, 250, pp (11 December 2013)
Abstract

Objectives: To investigate possible interactions visible on electroencephalogram recordings caused by concomitant administration of marbofloxacin and carprofen or cimicoxib in dogs without central nervous system disease. Methods: Totally 21 client-owned dogs undergoing different surgeries were...

Author(s)
Weil, C.; Tünsmeyer, J.; Tipold, A.; Hoppe, S.; Beyerbach, M.; Pankow, W. R.; Kästner, S. B.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2016, 57, 6, pp 311-317
Abstract

This study aimed to characterize bone cancer pain (quantitative sensory testing (QST), stance asymmetry index, actimetry, scores of pain and quality of life (QoL)) in dogs with appendicular osteosarcoma (OSA), and to evaluate a stepwise palliative analgesic treatment. The pain profile of thirteen...

Author(s)
Monteiro, B. P.; Lorimier, L. P. de; Moreau, M.; Beauchamp, G.; Blair, J.; Lussier, B.; Pelletier, J. P.; Troncy, E.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2018, 13, 12, pp e0207200
Abstract

Cimicoxib is a novel cyclooxygenase 2 inhibitor drug approved for use in dogs. Assessing pharmacokinetic profiles in target species is pivotal for extra-label applications. The purpose of the present study was to evaluate the pharmacokinetic profiles of cimicoxib after intragastric administration...

Author(s)
Kim TaeWon; Rocca, G. della; Salvo, A. di; Owen, H.; Sgorbini, M.; Giorgi, M.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2014, 34, 7, pp 923-925
AbstractFull Text

Cimicoxib (CX) is a new non-steroidal anti-inflammatory drug from the "coxib" family, designed for dogs. In the available literature there is little information on the pharmacokinetics of CX. The aim of this study was to evaluate the effect of food intake on the pharmacokinetic characteristics of ...

Author(s)
Łebkowska-Wieruszewska, B.; Kowalski, C. J.; Kim TaeWon; Owen, H.; Yun Hyoin; Giorgi, M.
Publisher
Polskie Towarzystwo Nauk Weterynaryjnych, Lublin, Poland
Citation
Medycyna Weterynaryjna, 2015, 71, 10, pp 626-631
Abstract

Objectives: To determine the efficacy and safety of cimicoxib (Cimalgex®; Vétoquinol SA) for the control of perioperative pain in dogs. Methods: A double-blind, randomized, controlled multi-centre field study was conducted in 237 dogs undergoing orthopaedic or soft tissue surgery. Pain was...

Author(s)
Grandemange, E.; Fournel, S.; Woehrlé, F.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2013, 54, 6, pp 304-312
Abstract

Background: Caesarean section of bitches is a well recognized painful condition in dogs and it can be classified as a soft tissue surgery. Cimicoxib, a newly registered NSAID in European Union has a claim for the relief of pain in peri-operative conditions. However, in case of caesarean section,...

Author(s)
Schneider, M.; Kuchta, A.; Dron, F.; Woehrlé, F.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2015, 11, 178, pp (31 July 2015)
AbstractFull Text

Author(s)
Jeunesse, E.; Lefevre, H.; Braun, J.; Iacroix, M.; Schneider, M.
Publisher
ASIS Biomedia s.l., Zaragoza, Spain
Citation
Argos - Informativo Veterinario, 2015, No.168, pp 76

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