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Abstract

To evaluate the effects of thiazide diuretics in dogs, 24-h urine excretion of calcium was measured in 6 clinically normal Beagles after administration of chlorothiazide (CTZ) for 2 weeks, administration of CTZ for 10 weeks, and administration of calcium carbonate and CTZ for 2 weeks. Compared with ...

Author(s)
Lulich, J. P.; Osborne, C. A.
Citation
American Journal of Veterinary Research, 1992, 53, 12, pp 2328-2332
Abstract

Author(s)
Stein, J. H.; Mauk, R. C.; Boonjarern, S.; Ferris, T. F.
Citation
Journal of Laboratory and Clinical Medicine, 1972, 79, No.6, pp 995-1003
Abstract

Studies were carried out in intact dogs, those with bilateral ureteral ligation, and nephrectomized animals. Under all the conditions both furosemide and chlorothiazide increased thoracic duct lymph flow. This action was extrarenal and was independent of diuresis.

Author(s)
Szwed, J. J.; Kleit, S. A.; Hamburger, R. J.
Citation
Journal of Laboratory and Clinical Medicine, 1972, 79, No.5, pp 693-700
Abstract

Nine mongrel dogs were anesthetized then injected i/v after a 20 minute stabilization period with 1, 3 or 5 mu g of norepinephrine and angiotensin, chlorothiazide. Dose-response relationships were determined before and after injections of chlorothiazide. Serum electrolytes, haematocrit, plasma...

Author(s)
Frohlich, E. D.; Thurman, A. E.; Pfeffer, M. A.; Brobmann, G. F.; Jacobson, E. D.
Citation
Proceedings of the Society for Experimental Biology and Medicine, 1972, 140, No.4, pp 1190-1196
Abstract

Author(s)
Fernandez, P. C.; Puschett, J. B.
Citation
American Journal of Physiology, 1973, 225, No.4, pp 954-961
Abstract

Hydrochlorothiazide, administered at 1, 3 and 9 mg/kg/day by mouth for 4 days, produced a dose-dependent lowering of plasma K and an elevation in plasma renin activity in unanaesthetized dogs. When plasma renin activity was suppressed in diuretic-treated dogs by the potent beta-adrenergic...

Author(s)
Sweet, C.; Gaul, S. L.
Citation
European Journal of Pharmacology, 1975, 32, 2, pp 370-374