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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

A dog was hospitalized after accidental overdose and extravasation of doxorubicin. With supportive care and dexrazoxane, systemic toxicity resolved by Day 9 and extravasation injury by Day 36. This case demonstrates that, with treatment, dogs can survive doxorubicin overdose and extravasation. The...

Author(s)
Kicenuik, K. S.; Northrup, N. C.; Clarke, D. M.; Bazzle, L. J.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Veterinary Journal, 2018, 59, 10, pp 1079-1084
Abstract

Carboplatin is a platinum chemotherapeutic agent commonly used in veterinary oncology that is currently classified as an irritant to local tissues when extravasated. To the authors' knowledge, there are no reports of vesicant injuries associated with carboplatin administration reported in the...

Author(s)
Miller, K. B.; Lejeune, A.; Regan, R.; Szivek, A.; Kow, K.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2018, 54, 6, pp 360-367
Abstract

This article summarizes prevention and treatment of lesions caused by extravasation of cytostatic drugs in place of their application, as well as dealing with systemic hypersensitive reactions to administered chemotherapy. Manipulation with cytostatic drugs, including catheter insertion, should be...

Author(s)
Pfeifr, J.; Škor, O.
Publisher
Profi Press, s.r.o., Praha 2, Czech Republic
Citation
Veterinářství, 2018, 68, 7, pp 462-466
Abstract

Vesicant chemotherapeutic drugs (e.g. doxorubicin, vincristine and vinblastine) are often used to treat multicentric lymphoma. A 9-year-old Beagle in Japan was diagnosed with stage III multicentric lymphoma [date not given]. The dog was affected by an extravazation after being administered about...

Author(s)
Tsujimura, S.; Maruo, T.; Namikawa, K.; Shida, T.
Publisher
Japanese Society of Veterinary Dermatology, Tokyo, Japan
Citation
Japanese Journal of Veterinary Dermatology, 2009, 15, 2, pp 83-87
Abstract

Strategies of treatment of lymphoma with drugs based on results of investigations of blood counts and echocardiography are considered. Methods of treatment are outlined including the use of prednisolone and prednisone, L-asparaginase, vincristine, cyclophosphamide, doxorubicin, methotrexate and...

Author(s)
Poudrai, M. P.
Publisher
NÉVA Europarc, Créteil, France
Citation
Le Nouveau Praticien Vétérinaire Canine - Féline, 2009, No.42, pp 29-36
Abstract

Most cytotoxic chemotherapy protocols used in small animals are designed to have a low risk of adverse effects; however, adverse events can occasionally occur. Timely and appropriate management of adverse events greatly increases client satisfaction and the likelihood of a successful treatment...

Author(s)
Thamm, D. H.; Vail, D. M.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2007, 43, 1, pp 1-7
Abstract

A 10-year-old female Boxer with mediastinal lymphoma, a 10-year-old female Bouvier des Flandres suffering from non-weight bearing lameness and swelling of soft tissues of the right forelimb, a 3-year-old American Pit Bull Terrier with multicentric stage IV lymphoma, a 9-year-old male Beagle with...

Author(s)
Spugnini, E. P.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2002, 221, 10, pp 1437-1440
Abstract

Subcutaneous vascular access systems which have been used in man for administering long term i/v chemotherapy, and have been used in a few animals, are described. Advantages are repeated access to the vascular system, decreased risk of extravasation of irritating drugs and patient mobility....

Author(s)
Bagley, R. S.; Flanders, J. A.
Citation
Compendium on Continuing Education for the Practicing Veterinarian, 1990, 12, 1, pp 22-24, 26-27
Abstract

A 10-month-old male Labrador Retriever with a 10-week history of stranguria, pollakiuria, haematuria, and urine retention had a large botryoid rhabdomyosarcoma resected from the trigonal region of the urinary bladder. A cuff of the ureteral mucosa was sutured to the bladder wall in an attempt to...

Author(s)
Senior, D. F.; Lawrence, D. T.; Gunson, C.; Fox, L. E.; Thompson, J. P.; Buergelt, C. D.
Citation
Journal of the American Animal Hospital Association, 1993, 29, 5, pp 386-390

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