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Abstract

Background: Canine progressive retinal atrophies are a group of hereditary retinal degenerations in dogs characterised by depletion of photoreceptor cells in the retina, which ultimately leads to blindness. PRA in the Lhasa Apso (LA) dog has not previously been clinically characterised or described ...

Author(s)
Hitti-Malin, R. J.; Burmeister, L. M.; Ricketts, S. L.; Lewis, T. W.; Pettitt, L.; Boursnell, M.; Schofield, E. C.; Sargan, D.; Mellersh, C. S.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genetics, 2020, 21, 100, pp (7 September 2020)
Abstract

Background: Progressive retinal atrophy (PRA) belongs to a group of inherited retinal disorders associated with gradual vision impairment due to degeneration of retinal photoreceptors in various dog breeds. PRA is highly heterogeneous, with autosomal dominant, recessive or X-linked modes of...

Author(s)
Kropatsch, R.; Akkad, D. A.; Frank, M.; Rosenhagen, C.; Altmüller, J.; Nürnberg, P.; Epplen, J. T.; Dekomien, G.
Publisher
BioMed Central Ltd, London, UK
Citation
Canine Genetics and Epidemiology, 2016, 3, 7, pp (8 July 2016)
Abstract

Cataracts are the leading cause of vision loss in dogs. Once they impair sight, there is no other recourse than to have phacoemulsification cataract removal with intraocular lens placement to restore optimal sight. Even early cataracts cause inflammation (lens-induced uveitis) and oxidative stress...

Author(s)
Colitz, C. M. H.
Publisher
Redstone Media Group, Peterborough, Canada
Citation
Journal of the American Holistic Veterinary Medical Association, 2018, 50, pp 36-41
Abstract

Objective: To describe ophthalmic, functional, structural, and genetical characteristics of progressive retinal atrophy (PRA) in the polski owczarek nizinny (PON) breed of dog. Animals studied clinically: Client-owned PON dogs (n=82) from Sweden. Procedures: Routine examination for presumed...

Author(s)
Svensson, M.; Olsén, L.; Winkler, P. A.; Petersen-Jones, S. M.; Bergström, T.; Garncarz, Y.; Narfström, K.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Ophthalmology, 2016, 19, 3, pp 195-205
Abstract

Background: Generalized progressive retinal atrophy (PRA) is a group of inherited eye diseases characterised by progressive retinal degeneration that ultimately leads to blindness in dogs. To date, more than 20 different mutations causing canine-PRA have been described and several breeds including...

Author(s)
Downs, L. M.; Wallin-Håkansson, B.; Bergström, T.; Mellersh, C. S.
Publisher
BioMed Central Ltd, London, UK
Citation
Canine Genetics and Epidemiology, 2014, 1, 4, pp (16 April 2014)
Abstract

Cataracts are the leading cause of vision loss in dogs. Once they impair sight, there is no other recourse than to have phacoemulsification cataract removal with intraocular lens placement to restore optimal sight. Even early cataracts cause inflammation (lens-induced uveitis) and oxidative stress...

Author(s)
Colitz, C. M. H.
Publisher
Redstone Media Group, Peterborough, Canada
Citation
Journal of the American Holistic Veterinary Medical Association, 2016, 45, pp 26-32
Abstract

Objective: To describe a slowly progressive retinopathy (SPR) in Shetland Sheepdogs. Animals: Forty adult Shetlands Sheepdogs with ophthalmoscopic signs of SPR and six normal Shetland Sheepdogs were included in the study. Procedure: Ophthalmic examination including slit-lamp biomicroscopy and...

Author(s)
Karlstam, L.; Hertil, E.; Zeiss, C.; Ropstad, E. O.; Bjerkås, E.; Dubielzig, R. R.; Ekesten, B.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Ophthalmology, 2011, 14, 4, pp 227-238
Abstract

Background: Dogs have the second largest number of genetic diseases, after humans. Among the diseases present in dogs, progressive retinal atrophy has been reported in more than a hundred breeds. In some of them, the mutation has been identified and genetic tests have allowed the identification of...

Author(s)
Aguirre-Hernández, J.; Wickström, K.; Sargan, D. R.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2007, 3, 14, pp (10 July 2007)
Abstract

Background: Mitotic terminally differentiated photoreceptors (PRs) are observed in early retinal degeneration (erd), an inherited canine retinal disease driven by mutations in the NDR kinase STK38L (NDR2). Results: We demonstrate that a similar proliferative response, but of lower magnitude, occurs ...

Author(s)
Gardiner, K. L.; Downs, L.; Berta-Antalics, A. I.; Santana, E.; Aguirre, G. D.; Genini, S.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2016, 17, 221, pp (11 March 2016)
Abstract

Retinopathy is a leading cause of blindness in the dog. Twenty vision-impaired dogs attended at our clinic of the National Taiwan University Veterinary Hospital (NTUVH) for ophthalmic examination and treatment. A retrospective study of these 20 dogs with a variety of retinopathies was performed....

Author(s)
Lin ChungTien; Yang WenYuan
Publisher
Chinese Society of Veterinary Science, Taipei, Taiwan
Citation
Taiwan Veterinary Journal, 2003, 29, 2, pp 90-96

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