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Veterinary information to support practice, based on evidence and continuing education

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Abstract

Successful male germ cell transplantation requires depletion of the host germ cells to allow efficient colonization of the donor spermatogonial stem cells. Although a sterilizing drug, busulfan, is commonly used for the preparation of recipient models before transplantation, the optimal dose of...

Author(s)
Hur TaiYoung; Lee SeungHoon; Ock SunA; Song Hyuk; Park HyunJung; Lee Ran; Sung SiHeung; Jhun HyunJhung; Lee WonYoung
Publisher
Korean Association for Laboratory Animal Science, Seoul, Korea Republic
Citation
Laboratory Animal Research, 2017, 33, 3, pp 264-269
Abstract

Although most anticancer drugs are administered intravenously, several of these drugs are currently available as pills, tablets and capsules. Some advantages of oral chemotherapy are the possibility of a practical, painless and well tolerated treatment. However, prescription of cytotoxic...

Author(s)
Calazans, S. G.; Paulino Júnior, D.; Alves, C. E. F.; Melo, I. H. de S.
Publisher
Editora Guará, São Paulo, Brazil
Citation
Clínica Veterinária, 2013, 18, 105, pp 50-55
Abstract

Author(s)
Moraes, R. C.; Paula, T. A. R. de; Fonseca, C. C.; Neves, M. T. D. das; Benjamin, L. dos A.
Publisher
Universidade Estadual do Ceará, Faculdade de Veterinaria, Ceará, Brazil
Citation
Ciência Animal , 2002, 12, 1, pp 57-65
Abstract

A two-year old male Welsh Corgi was referred for persistent thrombocytosis and occasional seizure. Hematological findings indicated marked thrombocytosis, eosinophilia, basophilia and moderate anemia. Bone marrow examination revealed marked megakaryocytic hyperplasia with morphologic abnormality. A ...

Author(s)
Mizukoshi, T.; Fujino, Y.; Yasukawa, K.; Matumoto, H.; Matsumura, S.; Nagasaki, T.; Ohno, K.; Tsujimoto, H.; Shimoda, T.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2006, 68, 11, pp 1203-1206
Abstract

Author(s)
Williams, L. E.
Publisher
Atlantic Coast Veterinary Conference, Atlantic City, USA
Citation
18th Annual Atlantic Coast Veterinary Conference, Trump Taj Mahal Resort Hotel, Atlantic City, New Jersey, USA, 17-20 October, 2005, 2005, pp unpaginated
Abstract

This is a practical guide to the correct use of 31 cytotoxic drugs for treating neoplasms in dogs and cats. The principles of tumour biology and anticancer therapy are described, as well as the chemotherapeutic agents, practical considerations (complications, safe handling of the drugs), specific...

Author(s)
Dobson, J. M.; Gorman, N. T.
Publisher
Blackwell Scientific Publications, Oxford, UK
Citation
Cancer chemotherapy in small animal practice., 1993, pp viii + 213 pp.
Abstract

Morphological and cytochemical characteristics of both bone marrow and peripheral blood cells, and the course of the disease, are described in a dog with acute myeloblastic leukaemia similar to the M-2 type (FAB classification) of man. Busulfan treatment had only a limited effect, mainly in...

Author(s)
Keller, P.; Sager, P.; Freudiger, U.; Speck, B.
Citation
Journal of Comparative Pathology, 1985, 95, 4, pp 619-632
Abstract

Dimethyl myleran (DMM), an antitumour drug effective against several rodent and human tumours, had severe haematopoietic toxicity but only moderate immunosuppressive activity in dogs. Of 18 dogs treated with 7.5-10 mg/kg DMM, followed by infusion of previously aspirated autologous marrow to protect ...

Author(s)
Weiden, P. L.; Storb, R.; Shulman, H.; Graham, T. C.
Citation
European Journal of Cancer, 1977, 13, 12, pp 1411-1415
Abstract

A new conservative therapy for the treatment of cycle disturbances in bitches is described; 33 animals were given a cytostatic, busulfan, and where necessary, additional progesterone, antibiotics and vitamins. Busulfan was given once or twice by mouth in doses of 3 mg/kg bodyweight. Treatment was...

Author(s)
Arbeiter, K.
Citation
Praktische Tierarzt, 1976, 57, 5, pp 295-296, 298, 300
Abstract

A review of the use of busulfan, cyclophosphamide, chlorambucil, melphalan, methotrexate, azathioprine, fluorouracil, cytosine arabinoside, vincristine, bleomycin, doxorubicin and other antineoplastic agents currently available.

Author(s)
Austie, B. A. M.; Rutteman, G. R.; Misdorp, W.
Citation
Tijdschrift voor Diergeneeskunde, 1988, 113, 6, pp 299-310

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