Autoimmune subepidermal blistering diseases (AISBDs) are rare skin disorders of animals that were first identified in dogs but several AISBDs are now recognised in other companion animal species. Most AISBDs in animals are homologues of the human diseases and are thought to share similar...
Author(s)
Bizikova, P.; Olivry, T.; Linder, K.; Rybnicek, J.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2023, 19, 55, pp (27 February 2023)
Background: In dogs, bullous pemphigoid (BP) is a subepithelial autoimmune disease, a rare dermatopathy in the clinical routine. BP is characterized by formation of vesicles and subepidermal blisters that result from dissolution of the dermalepithelial junction. Clinical signs of BP usually include ...
Author(s)
Dalegrave, S.; Fiorin, D. F. T.; Mansour, E. G.; Matos, M. R. de; Erdmann, R. H.; Flecke, L. R.; Azevedo, L. B. de; Oliveira, E. C. de
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2021, 49, (Suppl 1): 609,
Total RNA extracted from a papillomavirus-immortalized canine keratinocyte cell line and a cultured canine squamous carcinoma cell line SCC 2/88 were used to isolate fragments of cDNA encoding canine bullous pemphigoid antigen 2 (BPAg2, BP180) by reverse transcription-polymerase chain reaction and...
Author(s)
Xu LuTing; O'Toole, E. A.; Olivry, T.; Hernandez, C.; Peng Jun; Chen Mei; Chan, L. S.
Citation
Biochimica et Biophysica Acta, Molecular Basis of Disease, 2000, 1500, 1, pp 97-107
Bullous pemphigoid is a rare and severe autoimmune dermatosis caused by the production of autoantibodies. It has been reported in humans, dogs, cats and pigs, but, in horses, it has recently been reported in the USA. In Brazil, there were no references of the disease in horses. Due to the rarity of ...
Author(s)
Fontes, T. N.; Farias, S. S. de; Machado, G. A. C.; Mascarenhas, M. B.; Silva, A. L. da; Brandão, E. B.; Nogueira, V. de A.; Peixoto, T. da C.
Publisher
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro, Rio de Janerio, Brazil
Citation
Revista Brasileira de Medicina Veterinária, 2016, 38, Suppl. 1, pp 55-59
Human bullous pemphigoid (BP) is an immune-mediated blistering disease characterized by autoantibodies against BP antigens (230/180 kDa), which are constitutive glycoproteins of hemidesmosomes found in basal keratinocytes. Blistering diseases similar to human BP have been reported in dogs. IgG...
Author(s)
Iwasaki, T.; Olivry, T.; Lapiere, J. C.; Chan, L. S.; Peavey, C.; Liu, Y. Y.; Jones, J. C. R.; Ihrke, P. J.; Woodley, D. T.
Citation
Veterinary Pathology, 1995, 32, 4, pp 387-393
Laminin-332 (laminin-5) is a basement membrane heterotrimeric protein composed of alpha-3, beta-3 and gamma-2 laminin chains. Laminin-332 polypeptides are targeted by auto-antibodies in human patients with mucous membrane (cicatricial) pemphigoid or, more rarely, subepidermal vesicular diseases...
Author(s)
Olivry, T.; Bizikova, P.; Dunston, S. M.; Bond, R.; Halliwell, R.; Loeffler, A.; Pucheu-Haston, C. M.; Chen, M.; Marinkovich, M. P.
Publisher
Blackwell Publishing Ltd, Oxford, UK
Citation
Veterinary Dermatology, 2010, 21, 4, pp 345-357
Bullous pemphigoid is an autoimmune blistering human skin disease mediated by immunoglobulin (Ig)G autoantibodies targeting skin basement membrane component type XVII collagen, a transmembrane protein. Also designated BP180 and BPAG2, type XVII collagen is an extracellular matrix element essential...
Author(s)
Xu, L. T.; Olivry, T.; Chan, L. S.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Veterinary Dermatology, 2004, 15, 3, pp 146-151
Autoimmune diseases of the epidermal basement membrane are the result of the immune system self-activation against specific antigens of its essential structural elements. This group of skin diseases is characterized by the destruction of connecting bonds between the membrane zone and dermis, which...
Author(s)
Papadogiannakis, E. I.
Publisher
Hellenic Veterinary Medical Society, Athens, Greece
Citation
Deltion tes Ellenikes Kteniatrikes Etaireias = Journal of the Hellenic Veterinary Medical Society, 2005, 56, 1, pp 27-31
The skin, the largest animal body organ, constitutes a barrier against tissue damage from pathogens, resident microbiota, chemicals and environmental factors. In veterinary medical clinic, the main complaint in dogs and cats involves skin diseases, ranging from infections by pathogens to...
Author(s)
Ferreira, T. C.; Pinheiro, A. D. N.; Leite, A. K. R. de M.; Guedes, R. F. de M.; Pinheiro, D. C. S. N.
Publisher
Fedearl University of Ceará, Fortaleza, Brazil
Citation
Revista Brasileira de Higiene e Sanidade Animal, 2015, 9, 2, pp 299-319
The clinical signs, pathogenesis, diagnosis and treatment of pemphigus folicaeus, pemphigus erythromatosus, pemphigus vulgaris, mucous membrane pemphigoid, paraneoplastic pemphigus, bullous pemphigoid, epidermolysis bullosa acquisita, cutaneous lupus erythromatosus, vesicular cutaneous lupus...
Publisher
British Small Animal Veterinary Association, Quedgeley, UK
Citation
BSAVA manual of canine and feline dermatology, 2012, Ed.3, pp 206-214