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Abstract

Background: Stereotactic brain biopsy (SBB) is a technique that allows for definitive diagnosis of brain lesions. Little information is available regarding the diagnostic utility of SBB in dogs with intracranial diseases. Objective: To investigate the diagnostic accuracy (DA) of SBB in dogs with ...

Author(s)
Kani, Y.; Cecere, T. E.; Lahmers, K.; LeRoith, T.; Zimmerman, K. L.; Isom, S.; Hsu FangChi; Debinksi, W.; Robertson, J. L.; Rossmeisl, J. H.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2019, 33, 3, pp 1384-1391
Abstract

The treatment of intracranial lesions requires a precise diagnosis with subsequent identification of an adequate therapeutic approach. Stereotactic tumor biopsy may be considered the safest neurosurgical procedure in terms of anticipated results and potential surgical complications. The aim of the...

Author(s)
Müller, M.; Winkler, D.; Möbius, R.; Sauerstein, T.; Scholz, S.; Gutmann, S.; Flegel, T.; Meixensberger, J.; Drossel, W. G.; Grunert, R.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2019, 124, pp 79-84
Abstract

Background: Peripheral neuroblastic tumours arising from primitive cells of the cranial and spinal ganglia and from sympathetic ganglion cells of the autonomic nervous system include, from most to least differentiated, ganglioneuroma, ganglioneuroblastoma and neuroblastoma. Canine...

Author(s)
Salvadori, C.; Cantile, C.; Massari, F.; Chiti, L.; Colombo, S.; Abramo, F.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2019, 30, 4, pp 346-e100
Abstract

Objective: The objective of this pilot study was to describe the application and first preliminary data of a novel MRI and CT compatible patient-specific facemask for stereotactic brain biopsy of intracranial lesions in dogs. Methods: Five client-owned dogs presenting for neurological deficits...

Author(s)
James, M. D.; Bova, F. J.; Rajon, D. A.; Carrera-Justiz, S.; Clemmons, R. M.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2017, 58, 11, pp 615-621
Abstract

Objective: To develop and validate a three-dimensional (3D) brain phantom that can be incorporated into existing stereotactic headframes to simulate stereotactic brain biopsy (SBB) and train veterinary surgeons. Study design: Experimental study. Sample population: Canine brain phantoms were...

Author(s)
Sidhu, D. S.; Ruth, J. D.; Lambert, G.; Rossmeisl, J. H.
Publisher
Wiley, Boston, USA
Citation
Veterinary Surgery, 2017, 46, 5, pp 621-630
Abstract

This report describes the methodology, diagnostic yield, and adverse events (AE) associated with frame-based stereotactic brain biopsies (FBSB) obtained from 26 dogs with solitary forebrain lesions. Medical records were reviewed from dogs that underwent FBSB using two stereotactic headframes...

Author(s)
Rossmeisl, J. H.; Andriani, R. T.; Cecere, T. E.; Lahmers, K.; Leroith, T.; Zimmerman, K. L.; Gibo, D.; Debinski, W.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2015, 2, July, pp 20
Abstract

Cancer-testis antigens (CTAs) are a category of self proteins aberrantly expressed in diverse malignancies, mostly solid tumours, due to epigenetic de-repression. Normally expressed only in fetal or gametogenic tissues, CTAs are tantalizing immunotherapy targets, since autoimmunity risks appear...

Author(s)
Nemec, P. S.; Kapatos, A.; Holmes, J. C.; Stowe, D. M.; Hess, P. R.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2019, 17, 3, pp 317-328
Abstract

Two adult male dogs (a 7-year-old shorthaired Chihuahua and 14-year-old Shih Tzu) and one adult female dog (a 9-year-old Maltese) presented for evaluation of new-onset seizure activity. Magnetic resonance imaging of the brain demonstrated a large, poorly marginated T2-weighted hyperintense, and...

Author(s)
Levitin, H. A.; Foss, K. D.; Hague, D. W.; Connolly, S. L.; Vieson, M.; Wycislo, K. L.; Lezmi, S.; Lovett, M. C.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2019, 48, 2, pp 282-286
Abstract

CASE DESCRIPTION: Two 12-week-old Norwegian Buhunds from a litter of 5 were evaluated because of slowly progressive cerebellar ataxia and fine head tremors. Two other females from the same pedigree had been previously evaluated for similar signs. CLINICAL FINDINGS: Findings of general physical...

Author(s)
Mari, L.; Matiasek, K.; Jenkins, C. A.; Stefani, A. de; Ricketts, S. L.; Forman, O.; Risio, L. de
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2018, 253, 6, pp 774-780
Abstract

The focus of immunohistochemistry as applied to nervous system tumors is in identifying the neoplasm present and evaluating margins between normal and neoplastic tissue. Although not always utilized by specialists in neuropathology, immunohistochemistry remains useful to resolve concerns about the...

Author(s)
Johnson, G. C.; Coates, J. R.; Wininger, F.
Publisher
American College of Veterinary Pathologists Inc., Lawrence, USA
Citation
Veterinary Pathology, 2014, 51, 1, pp 146-160

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