Pigmented viral plaque is most commonly seen in Pug dogs in association with canine papillomavirus (CPV). In the present study, nucleic acid sequence and localization of viral genes were examined in 4 cases of pigmented viral plaque in Pug dogs. The results of polymerase chain reaction and nucleic...
Author(s)
Yu Miao; Chambers, J. K.; Tsuzuki, M.; Yamashita, N.; Ushigusa, T.; Haga, T.; Nakayama, H.; Uchida, K.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2019, 81, 11, pp 1643-1648
Triple negative basal like carcinoma is a rare and aggressive variant of a malignant mammary tumor in male dogs. The present work was conducted on 46 clinical cases suspected for canine mammary tumours collected over a period of 2 years. Out of 46 cases diagnosed as mammary tumour, one case was...
Author(s)
Gopal, K.; Srinivasan, P.; Thangathurai, R.; Rajeswar, J. J.; Dharmaceelan, S.
Publisher
Indian Association of Veterinary Pathologists, Izatnagar, India
Citation
Indian Journal of Veterinary Pathology, 2022, 46, 1, pp 73-77
A limited number of species, including men and dogs, spontaneously develop prostate cancer (PC). The histological and molecular relevance of canine PC as a model for the disease in men remains controversial. To address this challenge, this study aimed to assess the histomorphology and expression of ...
Author(s)
Brot, S. de; Lothion-Roy, J.; Grau-Roma, L.; White, E.; Guscetti, F.; Rubin, M. A.; Mongan, N. P.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2021, 20, 1, pp 38-49
Cutaneous papillomas (CPs) and cutaneous squamous cell carcinomas (CSCCs) are usual epidermal tumours in dogs. CPs and CSCCs probably arise from the neoplastic transformation of the keratinocytes within the stem cell compartment, since these cells are the only keratinocytes that would reside long...
Author(s)
Sanz Ressel, B. L.; Massone, A. R.; Barbeito, C. G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2021, 135, pp 366-370
Background: Studies pointed out that the tumor-infiltrating lymphocytes (TILs) have considerable importance in canine mammary tumor (CMT). On the other hand, cancer cells sometimes find ways to use immune checkpoint proteins as a shield to avoid being identified and attacked by the immune system as ...
Author(s)
Lopes-Neto, B. E.; Nunes-Pinheiro, D. C. S.; Carvalheira, J. G. V.; Schmitt, F.; Fátima Gärtner, M. de
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2021, 49, 1780,
Evidence is accumulating that tumour development is driven by cancer stem cells (CSCs). In order to understand the presence and potential contribution of stem cells (SCs) as tumour-initiating cells in canine cutaneous tumours, we selected three putative SC markers (Lgr5, Lgr6 and Sox9) and...
Author(s)
Bongiovanni, L.; Brachelente, C.; Moreno, E.; Welle, M. M.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2020, 7, 2,
In domestic animals, skin diseases are often diagnosed in small animal general practice (20-75% of the cases). Due to an uncontrolled proliferation of cells, that are unable to act accordingly to the signals that rule a normal cell behavior (division, growth), tumors develop. Consequently, this...
Author(s)
Barnea, R.; Velescu, S.; Kracunovic, M. C.; Dascălu, R.; Igna, C. D.; Morariu, S.
Publisher
Facultatea de Medicina Veterinara, Timisoara, Romania
Citation
Lucrari Stiintifice - Universitatea de Stiinte Agricole a Banatului Timisoara, Medicina Veterinara, 2022, 55, 4, pp 5-15
Expression of programmed cell death receptor ligand 1 (PD-L1) on tumor cells has been associated with immune escape in human and murine cancers, but little is known regarding the immune regulation of PD-L1 expression by tumor cells and tumor-infiltrating macrophages in dogs. Therefore, 14 canine ...
Author(s)
Hartley, G.; Faulhaber, E.; Caldwell, A.; Coy, J.; Kurihara, J.; Guth, A.; Regan, D.; Dow, S.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2017, 15, 2, pp 534-549
This study aimed to investigate the expression of receptor-type tumour endothelial marker 8 (TEM8RT) in canine mammary gland carcinomas (CMGCs) using immunohistochemistry and to evaluate the association between carcinoma cell TEM8RT expression and tumour histological features, histological grades...
Author(s)
Araki, M.; Noguchi, S.; Kubo, Y.; Yasuda, A.; Koh, M.; Otsuka, H.; Yokosuka, M.; Soeta, S.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Comparative Pathology, 2023, 200, pp 35-45
Background: Perianal (hepatoid) gland tumors are common in dogs, and the distinction between the benign and malignant forms is clinically important. Cytology of these tumors typically contains many large hepatoid cells and fewer small basal cells. Objectives: The objective of this study was to...
Author(s)
Evans, S. J. M.; Connolly, S. L.; Schaffer, P. A.; Vieson, M. D.; Stiles, A.; Moore, A. R.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2018, 47, 4, pp 634-637