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Abstract

Pigmented viral plaque is most commonly seen in Pug dogs in association with canine papillomavirus (CPV). In the present study, nucleic acid sequence and localization of viral genes were examined in 4 cases of pigmented viral plaque in Pug dogs. The results of polymerase chain reaction and nucleic...

Author(s)
Yu Miao; Chambers, J. K.; Tsuzuki, M.; Yamashita, N.; Ushigusa, T.; Haga, T.; Nakayama, H.; Uchida, K.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2019, 81, 11, pp 1643-1648
Abstract

Cutaneous papillomas (CPs) and cutaneous squamous cell carcinomas (CSCCs) are usual epidermal tumours in dogs. CPs and CSCCs probably arise from the neoplastic transformation of the keratinocytes within the stem cell compartment, since these cells are the only keratinocytes that would reside long...

Author(s)
Sanz Ressel, B. L.; Massone, A. R.; Barbeito, C. G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2021, 135, pp 366-370
Abstract

Background: Invasive micropapillary carcinoma (IMPC) is a rare malignant breast tumor and a variant form of invasive ductal carcinoma that is an aggressive neoplasm of the human breast and canine mammary gland. The importance of the tumor microenvironment in cancer development has gradually been...

Author(s)
Rodrigues, M. A.; Caldeira-Brant, A. L.; Gomes, D. A.; Silveira, T. L.; Chiarini-Garcia, H.; Cassali, G. D.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2021, 17, 130, pp (24 March 2021)
Abstract

Expression of programmed cell death receptor ligand 1 (PD-L1) on tumor cells has been associated with immune escape in human and murine cancers, but little is known regarding the immune regulation of PD-L1 expression by tumor cells and tumor-infiltrating macrophages in dogs. Therefore, 14 canine ...

Author(s)
Hartley, G.; Faulhaber, E.; Caldwell, A.; Coy, J.; Kurihara, J.; Guth, A.; Regan, D.; Dow, S.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2017, 15, 2, pp 534-549
Abstract

Evidence is accumulating that tumour development is driven by cancer stem cells (CSCs). In order to understand the presence and potential contribution of stem cells (SCs) as tumour-initiating cells in canine cutaneous tumours, we selected three putative SC markers (Lgr5, Lgr6 and Sox9) and...

Author(s)
Bongiovanni, L.; Brachelente, C.; Moreno, E.; Welle, M. M.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2020, 7, 2,
Abstract

Background: Perianal (hepatoid) gland tumors are common in dogs, and the distinction between the benign and malignant forms is clinically important. Cytology of these tumors typically contains many large hepatoid cells and fewer small basal cells. Objectives: The objective of this study was to...

Author(s)
Evans, S. J. M.; Connolly, S. L.; Schaffer, P. A.; Vieson, M. D.; Stiles, A.; Moore, A. R.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2018, 47, 4, pp 634-637
Abstract

The aim of this study was to investigate the expression of tumour endothelial marker 8 (TEM8) in canine mammary gland tumours (MGTs) by immunohistochemistry and to evaluate the association between tumour cell TEM8 expression and tumour histological features, histological grades and expression of...

Author(s)
Noguchi, S.; Araki, M.; Nakajima, K.; Koh, M.; Kokado, Y.; Kubo, Y.; Otsuka, H.; Yasuda, A.; Yokosuka, M.; Soeta, S.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Comparative Pathology, 2019, 173, pp 30-40
Abstract

The blood-testis barrier (BTB) consists of different cell-to-cell connections, including tight junction proteins like claudin-11 (CLDN11). For dogs, only limited data is published dealing with these proteins in general. Therefore, their physiological relevance, their postnatal expression, and their ...

Author(s)
Pörtner, C.; Rode, K.; Hollenbach, J.; Thiemeyer, H.; Beineke, A.; Günzel-Apel, A. R.; Brehm, R.
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2020, 148, pp 122-131
Abstract

Research using in vitro canine mammary cancer cell lines and naturally-occurring canine mammary tumors are not only fundamental models used to advance the understanding of cancer in veterinary patients, but are also regarded as excellent translational models of human breast cancer. Human breast...

Author(s)
Gray, M.; Turnbull, A. K.; Meehan, J.; Martínez-Pérez, C.; Kay, C.; Pang, L. Y.; Argyle, D. J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2020, 6, July,
AbstractFull Text

αB-crystallin is a member of a small family of thermal shock proteins that protects cells from stress. Because of lack of its expression in peripheral blood leukocytes, it was proposed as a molecular marker of circulating tumor cells in canine mammary gland tumors. The aim of the present study was...

Author(s)
Chmielewska-Krzesińska, M.; Jakimiuk, A.; Wąsowicz, K.
Publisher
Polish Academy of Sciences, Committee of Veterinary Sciences, Olsztyn-Kortowo II, Poland
Citation
Polish Journal of Veterinary Sciences, 2019, 22, 3, pp 523-529

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