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AbstractFull Text

BACKGROUND: Azathioprine is an immunosuppressive agent that is used in a variety of dermatologic, digestive and hematologic disorders in both humans and small animals. OBJECTIVES: The effects of long term Azathioprine administration on complete blood count, rate of CD4+ and CD8+ lymphocytes, serum...

Author(s)
Hassankhani, M.; Aldavood, S. J.; Khosravi, A.; Sasani, F.; Masoudifard, M.; Ansari, F.; Taheri, M.
Publisher
Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Citation
Iranian Journal of Veterinary Medicine, 2017, 11, 4, pp En361-En376, Pe38
Abstract

A 1.5-year-old female Bernese mountain dog was presented for a bilateral acute episcleritis associated with cutaneous nodules and upper respiratory tract signs. The diagnosis of systemic reactive histiocytosis was based on clinical findings and confirmed by histopathological analysis of cutaneous...

Author(s)
Bourguet, A.; Robin, E.; Chahory, S.
Publisher
Elsevier Masson, Issy-les Moulineaux Cedex, France
Citation
Revue Vétérinaire Clinique, 2019, 54, 1, pp 29-35
AbstractFull Text

This paper aimed at describing the first case of canine sporotrichosis in Espírito Santo, Brazil. Case: A 10 year-old Bull Terrier male dog was presented with nodular non-ulcerated lesions on the head and nodular ulcerated lesion on the nasal planum. The dog had a previous diagnosis of a low-grade...

Author(s)
Silva, L. T. da; Intra, N. R.; Ferraz, C. M.; Paz, J. S. da; Jesus Pinto, A. C. de; Sena, B. V. de; Santos Horta, R. dos; Braga, F. R.; Tobias, F. L.; Farias, P. C. G.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2019, 47, Supplement,
Abstract

OBJECTIVE: To investigate the cytotoxic effects of azathioprine, 6-mercaptopurine, and 6-thioguanine on canine hepatocytes. SAMPLE: Commercially available cryopreserved canine primary hepatocytes. PROCEDURES: The study consisted of 2 trials. In trial 1, hepatocytes were incubated with azathioprine, ...

Author(s)
LaDuke, K. E.; Ehling, S.; Cullen, J. M.; Bäumer, W.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2015, 76, 7, pp 649-655
Abstract

Canine uveodermatologic syndrome is an autoimmune disease that leads to the appearance of ophthalmic and dermatological signs, such as bilateral panuveitis, vitiligo, leukotrichia, alopecia and ulcerations. Due to the lack of information about the uveodermatologic syndrome, the objective of this...

Author(s)
Oliveira, A. T. C.; Oliveira, A. R. F. de; Santiago, I. L. T.; Lima, Y. B. S. de; Ferreira, T. C.
Publisher
Federal University of Ceará, Fortaleza, Brazil
Citation
Revista Brasileira de Higiene e Sanidade Animal, 2020, 14, 2, pp 248-261
Abstract

A pharmacodynamic assay has been previously developed to monitor ciclosporin treatment in dogs by assessing inhibition of cytokine transcription after whole blood stimulation with 12-myristate 13-1 acetate and ionomycin (PMA/I). In this study, whole blood stimulation with either PMA/I or...

Author(s)
Dandrieux, J. R. S.; Narayanan, L.; Firestone, S.; Archer, T. M.; Mansfield, C. S.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Medicine and Science, 2019, 5, 2, pp 199-205
AbstractFull Text

The aim of this study was to report a pemphigus-like lesions after topical use of mupirocin in dog. Case: An 1-year-old, uncastrated male, Poodle dog, weighing 13.8 kg was treated in a private clinic in Fortaleza. The main complaint was related to pruritus in abdominal and inguinal region, in...

Author(s)
Ferreira, T. C.; Medeiros Guedes, R. F. de; Bezerra, B. M. O.; Nunes-Pinheiro, D. C. S.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2019, 47, Supplement,
Abstract

A high rate of mortality, expense, and complications of immunosuppressive therapy in dogs underscores the need for optimization of drug dosing. The purpose of this study was to determine, using a flow-cytometric assay, the 50% T-cell inhibitory concentration (IC50) of dexamethasone, cyclosporine,...

Author(s)
Nafe, L. A.; Dodam, J. R.; Reineroc, C. R.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2014, 78, 3, pp 168-175
Abstract

Objective: Steroid-responsive meningitis arteritis SRMA is one of the most common inflammatory diseases of the central nervous system in dogs. The present study examined breed and sex predisposition factors based on the population of dogs in Germany as well as epidemiological and clinical factors...

Author(s)
Hilpert, E.; Tipold, A.; Meyerhoff, N.; Schwerdt, J.; Winkler, S.; Jurina, K.; Fischer, A.; Kornberg, M.; Fischer, A.; Kornberg, M.; Parzefall, B.; Flegel, T.
Publisher
Georg Thieme Verlag KG, Stuttgart, Germany
Citation
Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere, 2020, 48, 1, pp 5-12
Abstract

The objective of this report is to document a case of pneumatosis coli in an immunosuppressed dog successfully treated with supportive care that included hyperbaric oxygen. A 9 yr old, neutered male Maltese was presented for hematochezia of ∼36 h duration. The dog had a history of immune-mediated...

Author(s)
Fisk, A.; Allen-Durrance, A.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2019, 55, 4, pp e554-01

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