Malignant gliomas are associated with extremely poor clinical outcomes in both humans and dogs, and novel therapies are needed. Glioma-bearing canine patients may serve as promising preclinical models for human therapies, including complementary medicine. The objective of this study was to evaluate ...
Author(s)
Wright, A.; Watanabe, R.; Koehler, J. W.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2022, 9, 1,
Canine glioma is considered a potential model for human glioma, with recent studies of occurrence, therapy, and reclassification supporting the value of the canine model. The current diagnosis of canine glioma is based on morphologic criteria and immunohistochemistry (IHC), including...
Author(s)
Demeter, E. A.; Frank, C.; Rissi, D. R.; Porter, B. F.; Miller, A. D.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2019, 5, November,
Gliomatosis cerebri (GC) is a glioma subtype with diffuse neuroparenchymal infiltration without architectural distortion. GC was first used in human neuropathology and remained controversial until its elimination from the diagnostic lexicon in 2016. GC is currently defined as a diffuse growth...
Author(s)
Rissi, D. R.; Donovan, T. A.; Porter, B. F.; Frank, C.; Miller, A. D.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Veterinary Pathology, 2020, 58, 2, pp 293-304
A 23-week-old female intact American Bulldog was presented for a two-week history of progressive circling to the right, twitching, and altered mentation. Magnetic resonance imaging (MRI) revealed a non-contrast enhancing hemorrhagic mass centered in the right thalamus with concurrent subdural and...
Author(s)
Muller, K.; Kim Eunbee; Lebowitz, A.; Daverio, H.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2022, 9, 10,
Background: Gliomas in dogs remain poorly understood. Objectives: To characterize the clinicopathologic findings, diagnostic imaging features and survival of a large sample of dogs with glioma using the Comparative Brain Tumor Consortium diagnostic classification. Animals: Ninety-one dogs with...
Author(s)
José-Lopez, R.; Gutierrez-Quintana, R.; Fuente, C. de la; Manzanilla, E. G.; Suñol, A.; Castro, D. P.; Añor, S.; Sanchez-Masian, D.; Fernandez-Flores, F.; Ricci, E.; Marioni-Henry, K.; Mascort, J.; Matiasek, L. A.; Matiasek, K.; Brennan, P. M.; Pumarola, M.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2021, 35, 4, pp 1902-1917
This report describes a low-grade glial neoplasm (fibrillary astrocytoma) in a 5-year-old male boxer. The dog was presented for an intermittent left thoracic lameness of 5 days duration. Neurologic examination showed a cervical pain with a flaccid paresis associated with a lack of proprioception...
Author(s)
Guigo, P.; Bouhsina, N.; Deschamps, J. Y.; Dagher, E.; Chocteau, F.; Fusellier, M.
Publisher
Elsevier Masson, Issy-les Moulineaux Cedex, France
Citation
Revue Vétérinaire Clinique, 2020, 55, 3, pp 105-112
Tissue microarrays (TMAs) represent a useful technique for the simultaneous phenotyping of large sample numbers and are particularly suitable for histopathologic tumor research. In this study, TMAs were used to evaluate semiquantitatively the expression of multiple antigens in various canine...
Author(s)
Spitzbarth, I.; Heinrich, F.; Herder, V.; Recker, T.; Wohlsein, P.; Baumgärtner, W.
Publisher
American College of Veterinary Pathologists Inc., Lawrence, USA
Citation
Veterinary Pathology, 2017, 54, 3, pp 369-379
Doublecortin (DCX) and neuronal nuclear protein (NeuN) can be used as immunomarkers of neuronal progenitor cells and mature neurons, respectively. Increased DCX immunolabeling has been associated with tumor invasion in human gliomas and anaplastic canine meningiomas. These immunomarkers have not...
Author(s)
Elbert, J. A.; Rissi, D. R.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Veterinary Diagnostic Investigation, 2022, 34, 4, pp 757-760
Astrocytomas and oligodendrogliomas represent one third of histologically confirmed canine brain tumors. Our purpose was to describe the magnetic resonance (MR) imaging features of histologically confirmed canine intracranial astrocytomas and oligodendrogliomas and to examine for MR features that...
Author(s)
Young, B. D.; Levine, J. M.; Porter, B. F.; Chen-Allen, A. V.; Rossmeisl, J. H.; Platt, S. R.; Kent, M.; Fosgate, G. T.; Schatzberg, S. J.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Radiology & Ultrasound, 2011, 52, 2, pp 132-141
A 14-month-old male neutered Dobermann presented for investigations into lingual paresis, dysphagia and proprioceptive ataxia of the pelvic limbs. Magnetic resonance imaging (MRI) revealed a mass lesion in the brainstem. Treatment with glucocorticoids and radiation therapy (RT) achieved a good...
Author(s)
Manzanedo-Delgado, A.; Mason, S.; Pumarola, M.; Stabile, F.
Publisher
Wiley, Chichester, UK
Citation
Veterinary Record Case Reports, 2021, 9, 4,